Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

New studies shed light on the mechanism of childhood obesity

With the increase in childhood obesity and the associated increase in type 2 diabetes among children and adolescents, there is growing interest in how children's bodies process the foods they eat and how obesity and diabetes begin to develop at early ages.

18 Jun 2014

BIPI, Lilly announce resubmission of empagliflozin NDA to FDA for treatment of type 2 diabetes

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announced the resubmission of a New Drug Application (NDA) for the investigational sodium glucose co-transporter-2 (SGLT2) inhibitor empagliflozin for the treatment of adults with type 2 diabetes (T2D) to the U.S. Food and Drug Administration (FDA).

17 Jun 2014

No link between consumption of cow's milk-based formula and development of autoantibodies in kids

There is no correlation between the consumption of a cow's milk-based formula or hydrolyzed protein formula and the development of diabetes-associated autoantibodies in children younger than seven, according to a worldwide research study published in the Journal of the American Medical Association (JAMA).

17 Jun 2014

Researchers demonstrate potential of retinoic acid in preventing type 2 diabetes complications

At a time when obesity, type 2 diabetes, and their complications are a veritable epidemic worldwide, researchers at the University of Montreal and CHUM Research Centre (CRCHUM) recently demonstrated the potential of retinoic acid (RA), a derivative of Vitamin A, in treating obesity and type 2 diabetes and preventing their cardiovascular complications.

17 Jun 2014

Affordable Care Act to have significant impact on patients with diabetes

The Affordable Care Act (ACA, also known as Obamacare) is dramatically changing health care delivery in the U.S. Specific parts of the new law, which will be phased in through 2020, will have a significant impact on patients with diabetes and prediabetes, as explored in a comprehensive Review article published in Diabetes Technology & Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

17 Jun 2014

Mechanisms of recurrent bacteria AOM in children under scrutiny

The immune response in young children with bacterial acute otitis media differs between individuals who are prone to such infection and those who are not, US researchers have shown.

16 Jun 2014

Canola bread diet experiences reduction in blood glucose levels and LDL cholesterol

Canola is Canada's oil and new research from St. Michael's Hospital suggests it should also be one of the oils of choice for people with Type 2 diabetes.

16 Jun 2014

Bionic pancreas device controls blood sugar in patients with type 1 diabetes

The latest version of a bionic pancreas device has been successfully tested in two five-day clinical trials - one in adults, the other in adolescents - that imposed minimal restrictions on patient activities.

16 Jun 2014

Fasting converts bad cholesterol in fat cells to energy, combating diabetes risk factors

For prediabetics, many interventions focus on lifestyle changes and weight loss, but new research on periodic fasting has identified a biological process in the body that converts bad cholesterol in fat cells to energy, thus combating diabetes risk factors.

16 Jun 2014

Risk of breast cancer recurrence associated with carbohydrate intake

Dartmouth researchers have found that reducing carbohydrate intake could reduce the risk of breast cancer recurrence among women whose tumor tissue is positive for the IGF-1 receptor.

13 Jun 2014

Weight loss most important factor for improving cardiovascular health in obese OSA patients

Obesity and obstructive sleep apnea (OSA) tend to co-exist and are associated with a variety of cardiovascular risk factors, including inflammation, insulin resistance, abnormal cholesterol, and high blood pressure. While effective therapies are available for OSA, researchers are still unclear about what interventions are most effective in reducing the burden of risk factors for cardiovascular disease associated with OSA in obese patients.

13 Jun 2014

Study uncovers why statins increase diabetes risk

McMaster University researchers may have found a novel way to suppress the devastating side effect of statins, one of the worlds' most widely used drugs to lower cholesterol and prevent heart disease.

13 Jun 2014

Scientists are now one step closer to pill against obesity

Obesity and diabetes are among the fastest growing health problems in the world, and the hunt is in for a pill that can fight the problem.

13 Jun 2014

8.5 million on Medicare get opioids

The number of senior citizens getting narcotic painkillers and anti-anxiety medications under Medicare's prescription drug program is climbing sharply, and those older patients are being put on the drugs for longer periods of time, a USA TODAY examination of federal data shows.

12 Jun 2014

Auxilium and Prasco introduce authorized generic version of Testim

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, today announced that it has partnered with Prasco, LLC ("Prasco") to introduce an Authorized Generic version of Testim® (testosterone gel).

11 Jun 2014

Reducing carbohydrate intake could reduce risk of breast cancer recurrence

Dartmouth researchers have found that reducing carbohydrate intake could reduce the risk of breast cancer recurrence among women whose tumor tissue is positive for the IGF-1 receptor. The study, "Risk of Breast Cancer Recurrence Associated with Carbohydrate Intake and Tissue Expression of IGFI Receptor," will appear in the July issue of Cancer Epidemiology Biomarkers & Prevention.

11 Jun 2014

First Edition: June 11, 2014

Today's headlines include a range of stories about the upset of House Majority Leader Eric Cantor -- a Virginia primary election shocker -- as well as continuing coverage of health law implementation issues and congressional responses to the VA's health care troubles.

11 Jun 2014

Hydrolyzed formula does not lower diabetes linked autoantibodies in infants at risk for type 1 diabetes

Among infants at risk for type 1 diabetes, the use of a hydrolyzed formula (one that does not contain intact proteins) compared with a conventional formula did not reduce the incidence of diabetes-associated autoantibodies after 7 years of follow-up, according to a study in the June 11 issue of JAMA, a diabetes theme issue.

11 Jun 2014

Type 2 diabetes Patients who take metformin plus insulin at higher risk for heart disease, death

Patients with type 2 diabetes who take a combination of metformin plus insulin may be at higher risk for cardiovascular disease and death compared with those who take a combination of metformin plus sulfonylurea, according to a new study funded by the Agency for Healthcare Research and Quality that appears in the June 11 issue of JAMA.

11 Jun 2014

FDA grants orphan drug designation to EffRx Pharmaceuticals' EX404 for treatment of PCOS

EffRx Pharmaceuticals SA, a specialty pharmaceutical company, today announced that the U.S. Food and Drug Administration has granted orphan drug designation to its proprietary metformin-based product candidate, EX404, for the treatment of pediatric polycystic ovary syndrome (PCOS).

11 Jun 2014

Insulin News and Research

Further Reading

New studies shed light on the mechanism of childhood obesity

BIPI, Lilly announce resubmission of empagliflozin NDA to FDA for treatment of type 2 diabetes

No link between consumption of cow's milk-based formula and development of autoantibodies in kids

Researchers demonstrate potential of retinoic acid in preventing type 2 diabetes complications

Affordable Care Act to have significant impact on patients with diabetes

Mechanisms of recurrent bacteria AOM in children under scrutiny

Canola bread diet experiences reduction in blood glucose levels and LDL cholesterol

Bionic pancreas device controls blood sugar in patients with type 1 diabetes

Fasting converts bad cholesterol in fat cells to energy, combating diabetes risk factors

Risk of breast cancer recurrence associated with carbohydrate intake

Weight loss most important factor for improving cardiovascular health in obese OSA patients

Study uncovers why statins increase diabetes risk

Scientists are now one step closer to pill against obesity

8.5 million on Medicare get opioids

Auxilium and Prasco introduce authorized generic version of Testim

Reducing carbohydrate intake could reduce risk of breast cancer recurrence

First Edition: June 11, 2014

Hydrolyzed formula does not lower diabetes linked autoantibodies in infants at risk for type 1 diabetes

Type 2 diabetes Patients who take metformin plus insulin at higher risk for heart disease, death

FDA grants orphan drug designation to EffRx Pharmaceuticals' EX404 for treatment of PCOS

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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