Therapy News and Research

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Gaps in diabetes care identified

A symposium, sponsored by the American Journal of Nursing (AJN) in collaboration with the American Diabetes Association, the American Association of Diabetes Educators, Joslin Diabetes Center and the University of Pennsylvania School of Nursing identified barriers to, and strategies for, more effective diabetes self management and reaffirmed the nurse's critical role to facilitate better patient self care.

17 Jun 2007

Scientists step closer to curing genetic or acquired hearing loss

Researchers at the University of Virginia Health System have discovered a way to transfer genes, which they hope will restore hearing, into diseased tissue of the human inner ear.

17 Jun 2007

Discovery of IKBKE gene linked to breast cancer

Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers.

17 Jun 2007

How accurate are recovered memories?

A decade or so ago, a spate of high profile legal cases arose in which people were accused, and often convicted, on the basis of recovered memories.

17 Jun 2007

Solvay Pharmaceuticals submits supplemental NDA for AndroGel

Solvay Pharmaceuticals, Inc., has announced that it submitted a supplemental New Drug Application (sNDA) for AndroGel (testosterone gel) 1% CIII to the U.S. Food and Drug Administration (FDA) for treatment in male adolescents ages 13-17 years old with primary or secondary hypogonadism.

17 Jun 2007

Researchers culture blood-forming stem cells from human fat tissue

Researchers at the University of Pittsburgh School of Medicine have successfully isolated and cultured human hematopoietic stem cells from fat, or adipose, tissue, suggesting that they have found another important source of cells for reconstituting the bone marrow of patients undergoing intensive radiation therapy for blood cancers.

17 Jun 2007

Cognitive behavioral therapy workshops effective at getting men to seek help for insomnia

Despite the positive results that it brings in the treatment of insomnia, access to cognitive behavioral therapy (CBT) has been difficult given the limited awareness of CBT services amongst referrers such as primary care providers.

17 Jun 2007

New rheumatoid arthritis genes identified

Researchers at the University of Manchester have identified evidence of several new genes behind the chronic inflammatory disease rheumatoid arthritis (RA), which affects 387,000 people in the UK.

16 Jun 2007

Newer breast cancer drug may protect heart

By uncovering how one breast cancer drug protects the heart and another does not, Duke University Medical Center researchers believe they may have opened up a new way to screen drugs for possible heart-related side effects and to develop new drugs.

16 Jun 2007

Periodontal diseases are a threat to women of all ages

Two new studies in the June issue of the Journal of Periodontology (JOP) suggest that periodontal diseases are a threat to women of all ages due to hormonal fluctuations that occur at various stages of their lives.

15 Jun 2007

Nanosized bioceramic particles could function as efficient gene delivery vehicles with target specificity for the spleen

A detailed comparison of different types of ceramic nanoparticles has found that those made of silica can efficiently transport therapeutic genes to the spleen and trigger a potent immune response capable of attacking tumors.

14 Jun 2007

Trial shows nanoparticle-enabled thermal therapy safe for treating cancer

Several types of metal nanoparticles are capable of converting energy, such as that carried by near-infrared light or an oscillating magnetic field, into heat at a level high enough to kill tumors.

14 Jun 2007

Hybrid gold-dendrimer nanoparticles target and image tumors

Dendrimer nanoparticles, made of spherical, highly branched polymers, have shown promise as drug delivery vehicles capable of targeting tumors with large doses of anticancer drugs.

14 Jun 2007

Double-duty nanoparticles overcome drug resistance in tumors

Cancer cells, like bacteria, can develop resistance to drug therapy. In fact, research suggests strongly that multidrug resistant cancer cells that remain alive after chemotherapy are responsible for the reappearance of tumors and the poor prognosis for patients whose cancer recurs.

14 Jun 2007

Researchers create first 3-D optical images of human breast cancer in patients based on tissue fluorescence

Fluorescence diffuse optical tomography, or FDOT, relies on the presence of fluorophore molecules in tissue that re-radiate fluorescent light after illumination by excitation light of a different color.

14 Jun 2007

Newly found antibodies may be body's natural defense against Alzheimer's

In an important advance in the battle against Alzheimer's disease, physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have identified naturally occurring antibodies in human blood that may help to defend against this form of dementia as well as other neurodegenerative diseases.

14 Jun 2007

Thirteenth gene linked to Leber's congenital amaurosis

An international research team has discovered a gene that, when mutated, causes one of the most common forms of inherited blindness in babies.

14 Jun 2007

Priority review granted for oral formulation of HYCAMTIN (topotecan)

GlaxoSmithKline (GSK) has announced that its new drug application (NDA) for ORAL HYCAMTIN (topotecan) capsules, a treatment for relapsed small cell lung cancer (SCLC), has been granted Priority Review by the United States Food and Drug Administration (FDA).

14 Jun 2007

Eurand files NDA for Zentase for the treatment of exocrine pancreatic insufficiency

Eurand has announced that Eurand Pharmaceuticals Ltd. initiated the rolling submission of its new drug application (NDA) with the U.S. Food and Drug Administration (FDA) for Zentase for the treatment of Exocrine Pancreatic Insufficiency (EPI). Zentase (formerly EUR-1008), the company's lead product candidate, has been granted fast-track designation by the FDA.

14 Jun 2007