Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Phase 1 clinical study of unique vaccine to protect against COVID-19 begins

A unique vaccine to protect against COVID-19 begins clinical testing Tuesday, 6 April, at the Walter Reed Army Institute of Research (WRAIR), part of the U.S. Army Medical Research and Development Command.

5 Apr 2021

SARS-CoV-2 cryptic transmission modeling shows emergence of first wave in US and Europe

To analyze this cryptic transmission phase and the first wave of the pandemic that ensued, researchers from Italy, UK, and the US used a data-driven, spatial, stochastic, and age-structured epidemic model. They developed a mechanistic understanding of the evolution of the epidemic and estimated the time required for local transmission in various states and countries. The model developed by the team offers a statistical idea of SARS-CoV-2 introductions across European countries and many states in the US.

5 Apr 2021

The use of mammalian cell surface display for rapid characterization of SARS-CoV-2 variants

A research group from the U.S. demonstrated the practicality of a spike display system in order to accelerate vaccine design, but also to swiftly appraise the effects of mutations in emerging strains of the SARS-CoV-2.

5 Apr 2021

RNA-binding cylinders inhibit SARS-CoV-2 replication in vitro

Research led by Michael J. Hannon from the University of Birmingham, UK, finds metallo-supramolecular helicates (cylinders) binding to untranslated regions of SARS-CoV-2 suppresses viral replication. The untranslated regions (UTR) of the viral genome could serve as drug targets for antiviral treatment.

5 Apr 2021

Scientists use a novel two-step method to track receptor proteins

The neurons in our nervous system "talk" to each other by sending and receiving chemical messages called neurotransmitters.

3 Apr 2021

Scientists identify nine potential new COVID-19 treatments

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases.

2 Apr 2021

Unique approach to heart-liver transplant offers new hope for highly sensitized patients

All too often, patients with high levels of antibodies face major challenges getting a transplant. These highly sensitized patients have a much higher risk of death while waiting for suitable organs they are less likely to reject.

1 Apr 2021

Study discovers new target on SARS-CoV-2 spike for protective antibodies

Researchers at The Scripps Research Institute, USA, have described a potential target for COVID-19 vaccines. Dubbed as CC40.8 bnAb, it exhibited broad reactivity with human beta coronaviruses.

1 Apr 2021

Can asymptomatic COVID-19 confer long-term immunity?

Researchers examined the antibody responses in symptomatic and asymptomatic individuals recovered from COVID-19 to see if there was a discernable difference in their humoral immune responses and long-term protection from reinfection with SARS-CoV-2.

1 Apr 2021

Glycans influence SARS-CoV-2 spike–ACE2 binding affinity, finds study

A study conducted at the Los Alamos National Laboratory, USA, and Concordia University, Canada, has explored the impact of different types of glycans on the interaction between SARS-CoV-2 spike protein and human ACE2 receptor.

1 Apr 2021

Researchers develop a recombinant SARS-CoV-2 receptor-binding domain trimer vaccine candidate

New research deals with the development of RBD trimer as a potent target for SARS-CoV-2 subunit vaccines. This study revealed the development of a trimeric RBD subunit vaccine candidate that could induce strong humoral and cellular immune responses in nonhuman primates (NHPs), namely, rhesus macaques.

1 Apr 2021

Bethyl Wins the CiteAb Researchers’ Choice Award

Bethyl Laboratories, Inc., a leading supplier of antibody products and custom antibody services, has won the 2021 CiteAb Researchers’ Choice Award. The CiteAb awards recognize both suppliers and individuals who make notable contributions in the life sciences reagent sector.

From Bethyl Laboratories, Inc. 1 Apr 2021

Bethyl Wins the CiteAb Researchers’ Choice Award

From Bethyl Laboratories, Inc. 1 Apr 2021

Antibodies produced from infection with SARS-CoV-2 501Y.V2 protect against other variants

A recent paper in the journal Nature shows that while earlier lineages do not elicit antibodies capable of efficiently neutralizing the newly emerged South African variant, SARS-CoV-2 501Y.V2 (B.1.351), the converse does occur.

31 Mar 2021

Oxford-AstraZeneca vaccine effective against B.1.1.7 SARS-CoV-2 variant

Published in The Lancet, the study explores if the Oxford-AstraZeneca vaccine works well in protecting against the B.1.1.7 variant, otherwise known as the U.K. variant.

31 Mar 2021

Antibody tests, even rapid finger pricks, are effective COVID-19 screening tools

New findings from a Michigan Medicine study reveal that antibody testing is predictive of prior COVID-19 infection, and rapid screening methods - even from finger pricks - are effective testing tools.

31 Mar 2021

Risk of SARS-CoV-2 from reinfected individuals with previous infection or vaccination

A technical report recently published by the European Center for Disease Prevention and Control (ECDC) has summarized all available literature regarding the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from asymptomatic reinfected individuals with a history of SARS-CoV-2 infection or vaccination.

31 Mar 2021

New mRNA COVID-19 vaccine candidate shows promise in vivo

Researchers report that a new lipid nanoparticle mRNA coronavirus disease 2019 (COVID-19) vaccine candidate protected 70% of mice expressing the human angiotensin-converting enzyme 2 (ACE2), while all the non-vaccinated mice died.

31 Mar 2021

Researchers evaluate antibodies that inhibit SARS-CoV-2 RBD variants with a novel assay

A team of researchers recently discussed the potential role of a new assay in bridging a major gap in SARS-CoV-2 research. This assay can throw light on 1) the selection of complementary monoclonal antibody candidates and 2) rapid identification of the immune escape to emerging RBD variants following vaccination or natural infection.

31 Mar 2021

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

The ongoing COVID-19 pandemic, caused by SARS-CoV-2, is now established to be more likely to lead to symptomatic and serious illness in males relative to females. This may extend as far back as pregnancy, suggests a recent study.

31 Mar 2021

Antibody News and Research

Further Reading

Phase 1 clinical study of unique vaccine to protect against COVID-19 begins

SARS-CoV-2 cryptic transmission modeling shows emergence of first wave in US and Europe

The use of mammalian cell surface display for rapid characterization of SARS-CoV-2 variants

RNA-binding cylinders inhibit SARS-CoV-2 replication in vitro

Scientists use a novel two-step method to track receptor proteins

Scientists identify nine potential new COVID-19 treatments

Unique approach to heart-liver transplant offers new hope for highly sensitized patients

Study discovers new target on SARS-CoV-2 spike for protective antibodies

Can asymptomatic COVID-19 confer long-term immunity?

Glycans influence SARS-CoV-2 spike–ACE2 binding affinity, finds study

Researchers develop a recombinant SARS-CoV-2 receptor-binding domain trimer vaccine candidate

Bethyl Wins the CiteAb Researchers’ Choice Award

Bethyl Wins the CiteAb Researchers’ Choice Award

Antibodies produced from infection with SARS-CoV-2 501Y.V2 protect against other variants

Oxford-AstraZeneca vaccine effective against B.1.1.7 SARS-CoV-2 variant

Antibody tests, even rapid finger pricks, are effective COVID-19 screening tools

Risk of SARS-CoV-2 from reinfected individuals with previous infection or vaccination

New mRNA COVID-19 vaccine candidate shows promise in vivo

Researchers evaluate antibodies that inhibit SARS-CoV-2 RBD variants with a novel assay

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

Antibodies eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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