Genes News and Research

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Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Researchers investigated the tropism of SC2r-CoVs infecting Rhinolophus bats.

18 Apr 2023

IOB researchers identify an active multi-layer embryonic brain circuit

Using a new approach for studying live embryonic mouse brains at single-cell resolution, researchers have identified an active multi-layer circuit that forms in the cortex during an unexpectedly early stage of development. Perturbing the circuit genetically led to changes similar to those seen in the brains of people with autism. The findings are reported today in Cell by a team based at the Institute of Molecular and Clinical Ophthalmology Basel.

18 Apr 2023

Lipid molecules enable uptake of therapies into the brain after a stroke

To get therapies into the brain after a stroke, researchers are increasingly making use of the blood–brain barrier, which allows only certain molecules to pass from the blood into the brain.

17 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Understanding the prevalence and dissemination aminoglycoside resistance genes

Choosing the appropriate antibiotics to treat bacterial infections has grown more challenging because of the emergence of antibiotic-resistant bacteria.

17 Apr 2023

People with Down syndrome are living longer, but the health system still treats many as kids

It took Samantha Lesmeister's family four months to find a medical professional who could see that she was struggling with something more than her Down syndrome.

17 Apr 2023

Uncovering the connection between the microbiome and aging

Researchers evaluated the recent advances in understanding how the microbiome influences aging and associated diseases.

15 Apr 2023

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled - a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease.

13 Apr 2023

New clinical RNA sequencing platform helps carve a path for Precision Child Health

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver individualized care for every patient.

13 Apr 2023

New AI tool accurately predicts aggressiveness of colorectal cancer

A new artificial intelligence model designed by researchers at Harvard Medical School and National Cheng Kung University in Taiwan could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer, the second deadliest cancer worldwide.

13 Apr 2023

Researchers show how the EBV virus exploits genomic weaknesses to cause cancer

The Epstein-Barr virus (EBV) is easily spread through bodily fluids, primarily saliva, such as kissing, shared drinks or using the same eating utensils.

13 Apr 2023

Curtin researchers identify the genetic signature of pre-malignant liver cells

Researchers at Curtin University have identified the genetic signature of pre-malignant liver cells, offering potentially significant implications for the almost 3,000 Australians diagnosed with the deadly cancer each year.

13 Apr 2023

Genomic study reveals Babesia duncani's pathogenicity and virulence

'Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between May and October by a tick.

13 Apr 2023

Changes to tumor DNA can help predict cancer's next move

Knowing whether a tumor might grow or spread to other parts of a patient’s body could be key to survival – and now scientists are one step closer to unlocking the ability to predict just that.

13 Apr 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

Genes News and Research

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

IOB researchers identify an active multi-layer embryonic brain circuit

Lipid molecules enable uptake of therapies into the brain after a stroke

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

Understanding the prevalence and dissemination aminoglycoside resistance genes

People with Down syndrome are living longer, but the health system still treats many as kids

Uncovering the connection between the microbiome and aging

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

New clinical RNA sequencing platform helps carve a path for Precision Child Health

New AI tool accurately predicts aggressiveness of colorectal cancer

Researchers show how the EBV virus exploits genomic weaknesses to cause cancer

Curtin researchers identify the genetic signature of pre-malignant liver cells

Genomic study reveals Babesia duncani's pathogenicity and virulence

Changes to tumor DNA can help predict cancer's next move

Research reveals molecular features of rare mtDNA mutations

How to combat and lessen seasonal allergy symptoms

New tool provides insight into the developmental history of certain immune cells

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

Pediatric invasive group A Streptococcal infections on the rise during respiratory virus outbreak

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo