Membrane News and Research

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Novel approach promises easier way to detect protein fibers implicated in neuro-degenerative diseases

Liquid crystals are familiar to most of us as the somewhat humdrum stuff used to make computer displays and TVs. Even for scientists, it has not been easy to find other ways of using them.

24 Sep 2015

New genetic cause identified for congenital heart arrhythmia

Scientists at The Ohio State University Dorothy M. Davis Heart and Lung Research Institute have identified a new genetic cause for congenital heart arrhythmia. The results of their research are published online by the Proceedings of the National Academy of Sciences (PNAS).

23 Sep 2015

UCI scientists find potential biomarker for diagnosing certain forms of autism

By identifying a key signaling defect within a specific membrane structure in all cells, University of California, Irvine researchers believe, they have found both a possible reliable biomarker for diagnosing certain forms of autism and a potential therapeutic target.

22 Sep 2015

Researchers develop new method to capture how brain cells interact

Interactions between brain cells hold the key to healthy brain function and cognition, but many of those interactions are notoriously difficult to study.

21 Sep 2015

Researchers discover new import pathway used by proteins to reach mitochondria

Mitochondria serve as the powerhouses of the cell, converting the energy stored in foods into a form cells can use. When this important task fails, it can result in numerous diseases, particularly those affecting organs with a high energy consumption like the brain or the heart.

18 Sep 2015

Cautiously-designed combination therapies may attenuate side effects associated with Alzheimer's drugs

BACE1 is the major drug target for Alzheimer's disease, but we know surprisingly little about its normal function in the CNS.

15 Sep 2015

Researchers use nanopore technology for early detection of colorectal and lung cancers

Using tiny "nanopore" scanners that can detect individual DNA molecules, Professor Amit Meller and colleagues are on the hunt for biological markers in cancer cells that may help clinicians diagnose colorectal and lung cancers at their earliest stages.

10 Sep 2015

Compound responsible for chilis' heat may help kill prostate cancer cells

Capsaicin, the compound responsible for chilis' heat, is used in creams sold to relieve pain, and recent research shows that in high doses, it kills prostate cancer cells. Now researchers are finding clues that help explain how the substance works. Their conclusions suggest that one day it could come in a new, therapeutic form.

10 Sep 2015

Latest ENT research to be presented at AAO-HNSF's annual meeting

The latest research on hearing loss, head and neck cancers, sleep apnea and other otolaryngic topics will be presented in Dallas, TX, September 27-30, at the 2015 Annual Meeting & OTO EXPO? of the American Academy of Otolaryngology--Head and Neck Surgery Foundation (AAO-HNSF), the largest annual meeting of ear, nose, throat, head and neck physicians in the world.

9 Sep 2015

Scientists identify new drug target to treat heart arrhythmias

Scientists at The Ohio State University Davis Heart and Lung Research Institute have identified a new target they hope will help make the next drug discovery for patients suffering from heart arrhythmias happen sooner.

9 Sep 2015

Resin contains substances that may cure epilepsy, say Linköping University researchers

Sticky resin from conifers contains substances that could relieve or cure epilepsy. Researchers at Linköping University have synthesized and tested 71 substances known as resin acids, of which twelve are prime candidates for new medicines.

9 Sep 2015

Oxis Biotech executes worldwide license agreement to develop, commercialize novel cancer therapy

Oxis Biotech, Inc., a wholly owned subsidiary of Oxis International, Inc., announced today the execution of an exclusive worldwide license agreement to further develop and commercialize DT2219ARL, a novel therapy for the treatment of various human B cell cancers, leukemias and lymphomas.

8 Sep 2015

RAB35 protein plays role in oncogenic process

A protein known to play a role in transporting the molecular contents of normal cells into and out of various intracellular compartments can also turn such cells cancerous by stimulating a key growth-control pathway.

4 Sep 2015

Researchers one step closer to developing asthma vaccine

Researchers at VIB (a leading life sciences institute in Flanders, Belgium) and Ghent University have successfully established a causal relationship between exposure to so-called farm dust and protection against asthma and allergies.

4 Sep 2015

Cells expressing faulty CFTR channel to TNF-α can 'fix' cystic fibrosis cells

Scientific experiments examining what happens to the faulty channel protein that causes cystic fibrosis during inflammation have yielded unexpected and exciting results. The study, conducted by Sara Bitam and her colleagues at INSERM in France, has just passed peer review on open science publishing platform F1000Research.

3 Sep 2015

Novel approach to reduce 'bad' lipids in blood circulation

Xian-Cheng Jiang, PhD, professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering "bad" lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis. The research was published in the online edition of Gastroenterology.

3 Sep 2015

Inhalation exposure to PM2.5 pollution triggers liver fibrosis

A research team led by Kezhong Zhang, Ph.D., at the Wayne State University School of Medicine's Center for Molecular Medicine and Genetics, has discovered that exposure to air pollution has a direct adverse health effect on the liver and causes liver fibrosis, an illness associated with metabolic disease and liver cancer.

3 Sep 2015

Novel chemical virus can cross double lipid layer surrounding cells to release drugs

Viruses are able to redirect the functioning of cells in order to infect them. Inspired by their mode of action, scientists from the CNRS and Université de Strasbourg have designed a "chemical virus" that can cross the double lipid layer that surrounds cells, and then disintegrate in the intracellular medium in order to release active compounds.

29 Aug 2015

Scientists reveal role of dynamin and show how specific mutations impair function of dynamin

Cells continually form membrane vesicles that are released into the cell. If this vital process is disturbed, nerve cells, for example, cannot communicate with each other. The protein molecule dynamin is essential for the regulated formation and release of many vesicles.

28 Aug 2015

Researchers uncover important cellular functions that help regulate inflammation

Researchers at the Virginia Bioinformatics Institute at Virginia Tech have uncovered key cellular functions that help regulate inflammation -- a discovery that could have important implications for the treatment of allergies, heart disease, and certain forms of cancer.

28 Aug 2015

Membrane News and Research

Novel approach promises easier way to detect protein fibers implicated in neuro-degenerative diseases

New genetic cause identified for congenital heart arrhythmia

UCI scientists find potential biomarker for diagnosing certain forms of autism

Researchers develop new method to capture how brain cells interact

Researchers discover new import pathway used by proteins to reach mitochondria

Cautiously-designed combination therapies may attenuate side effects associated with Alzheimer's drugs

Researchers use nanopore technology for early detection of colorectal and lung cancers

Compound responsible for chilis' heat may help kill prostate cancer cells

Latest ENT research to be presented at AAO-HNSF's annual meeting

Scientists identify new drug target to treat heart arrhythmias

Resin contains substances that may cure epilepsy, say Linköping University researchers

Oxis Biotech executes worldwide license agreement to develop, commercialize novel cancer therapy

RAB35 protein plays role in oncogenic process

Researchers one step closer to developing asthma vaccine

Cells expressing faulty CFTR channel to TNF-α can 'fix' cystic fibrosis cells

Novel approach to reduce 'bad' lipids in blood circulation

Inhalation exposure to PM2.5 pollution triggers liver fibrosis

Novel chemical virus can cross double lipid layer surrounding cells to release drugs

Scientists reveal role of dynamin and show how specific mutations impair function of dynamin

Researchers uncover important cellular functions that help regulate inflammation

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