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SARS-CoV-2 cytokine storm inhibited by curcumin nanoparticles

In a recent study published in the journal ACS Applied Bio Materials, researchers demonstrated the inhibitory potential of curcumin-encapsulated polysaccharide nanoparticles (CUR−PS-NPs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (CoV2-SP)-stimulated cytokine storm in lung and liver epithelial cells.

8 Feb 2022

Memory B cells induced by mRNA vaccine may help generate antibodies against Omicron

In a recent research article published in the journal of Science Immunology, a team of researchers from Japan performed longitudinal analysis on the cellular composition of receptor-binding domain (RBD) memory B cell subsets and its antibody binding and neutralizing activity against the Beta, Delta, and Omicron variants following the second dose of a messenger ribonucleic acid (mRNA) vaccine.

8 Feb 2022

Assessing the association of COVID-19 and Immunoglobulin A vasculitis in children

In a recent study posted to the Research Square* preprint server, researchers conducted a systematic review to investigate any association between immunoglobulin A (IgA) vasculitis and coronavirus disease 2019 (COVID-19) in children.

8 Feb 2022

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

The fight against the COVID-19 pandemic is an international scientific challenge regarding the search for strategies to fight the viral infection and prevent its damaging consequences.

7 Feb 2022

Investigating taraxerol as a protease inhibitor against SARS-CoV-2

In a recent study posted to the Research Square preprint* server, a team of researchers investigated the toxicity and absorption, distribution, metabolism, and excretion (ADME) characteristics of a potent herbal drug, taraxerol, in the management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The paper is under consideration for publication in the Structural Chemistry journal.

7 Feb 2022

SARS-CoV-2 infection-induced antibodies may last more than 20 months

A recent research letter published in the JAMA demonstrated the prevalence and the longevity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in coronavirus disease 2019 (COVID-19) unvaccinated United States (US) adults recovered from the disease in the long term.

7 Feb 2022

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

In a recent research paper published in the journal Infection, the scientists estimated the transmission and disease severity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant and the effectiveness of the current coronavirus disease 2019 (COVID-19) vaccines against the same by conducting a literature review. Further, a meta-analysis was conducted to obtain a numeric estimate of the vaccine effectiveness against the Delta variant.

7 Feb 2022

Novel fast-spreading HIV-1 variant found circulating in the Netherlands

Researchers identify 17 individuals who were infected with a highly virulent variant of HIV-1.

7 Feb 2022

Study shows chronic alcohol consumption as a potential risk factor for SARS-CoV-2-infection

In a study posted to the bioRxiv* preprint server, a team of researchers from Germany studied the expression data of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-relevant genes such as angiotensin-converting enzyme 2 (ACE2), transmembrane serine protease 2 (TMPRSS2), and the G-protein coupled receptor Mas in an alcohol-exposed rodent model infected with SARS-CoV-2.

7 Feb 2022

SARS-CoV-2 infection can elevate the risk of serious complications during pregnancy

Pregnant individuals infected with SARS-CoV-2, the virus that causes COVID-19, are about 40% more likely to develop serious complications or die during pregnancy than those who aren’t infected with the virus, according to a nationwide study led by a University of Utah Health obstetrician.

7 Feb 2022

Novel, rapid and efficient assay for SARS-CoV-2 neutralizing antibodies

Researchers validate a quick, highly efficient, and automated assay to detect neutralizing antibodies against SARS-CoV-2.

7 Feb 2022

Fever the dominant symptom in SARS-CoV-2 Alpha- and Delta-infected children

Researchers assess the different clinical symptoms of SARS-CoV-2 infection in children and adolescents across different time periods.

7 Feb 2022

Pregnant women with COVID-19 may be at greater risk for pregnancy complications

Pregnant women with COVID-19 appear to be at greater risk for common pregnancy complications — in addition to health risks from the virus — than pregnant women without COVID-19, suggests a study funded by the National Institutes of Health.

7 Feb 2022

mRNA-based COVID-19 booster vaccination shown to protect against severe omicron infection in macaques

Scientists recently evaluated the effectiveness of a booster dose of the Moderna-developed COVID-19 vaccine and omicron spike-specific mRNA vaccine in non-human primates that are primed with the Moderna vaccine.

7 Feb 2022

Colchicine holds promise to reduce the risk of severe COVID-19

A recent article, published in Rheumatology and Therapy, reviews the potent evidence of colchicine against the SARS-CoV-2 infection.

7 Feb 2022

Investigating the immunology of COVID-19 infected children

Researchers published a new study that focused on the key principles of developmental immunology associated with immunobiology and the clinical impacts of COVID-19 infections in children and adults.

7 Feb 2022

Omicron sequences containing Delta mutation detected during SARS-CoV-2 genomic surveillance

This research letter published in Emerging Infectious Diseases warns scientists to interpret unusual mutations with caution.

7 Feb 2022

COVID-19 patients are at high risk of developing heart problems up to a year after infection

An analysis of federal health data indicates that people who have had COVID-19 are at increased risk of developing cardiovascular complications within the first month to a year after infection, according to researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System.

7 Feb 2022

Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Researchers have been investigating sarbecovirus lineages and the ability of those lineages to evolve the ability to bind ACE2.

7 Feb 2022

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

A new study analyzes neutralizing antibodies and T-cell responses targeting the SARS-CoV-2 D614G, as well as some variants of concern.

7 Feb 2022

SARS News and Research

SARS-CoV-2 cytokine storm inhibited by curcumin nanoparticles

Memory B cells induced by mRNA vaccine may help generate antibodies against Omicron

Assessing the association of COVID-19 and Immunoglobulin A vasculitis in children

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

Investigating taraxerol as a protease inhibitor against SARS-CoV-2

SARS-CoV-2 infection-induced antibodies may last more than 20 months

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

Novel fast-spreading HIV-1 variant found circulating in the Netherlands

Study shows chronic alcohol consumption as a potential risk factor for SARS-CoV-2-infection

SARS-CoV-2 infection can elevate the risk of serious complications during pregnancy

Novel, rapid and efficient assay for SARS-CoV-2 neutralizing antibodies

Fever the dominant symptom in SARS-CoV-2 Alpha- and Delta-infected children

Pregnant women with COVID-19 may be at greater risk for pregnancy complications

mRNA-based COVID-19 booster vaccination shown to protect against severe omicron infection in macaques

Colchicine holds promise to reduce the risk of severe COVID-19

Investigating the immunology of COVID-19 infected children

Omicron sequences containing Delta mutation detected during SARS-CoV-2 genomic surveillance

COVID-19 patients are at high risk of developing heart problems up to a year after infection

Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

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