Genes News and Research

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Transcription of genes is fast but sloppy in old age

In a large joint project, a total of six research groups from the University of Cologne Cluster of Excellence on Cellular Stress Responses in Age-Associated Diseases (CECAD), the Max Planck Institute for Biology of Aging (MPI) in Cologne and the University of Göttingen have demonstrated the following findings which apply across the animal kingdom: with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers.

12 Apr 2023

The international spread of drug-resistant Shigella sonnei

Researchers examined the international dissemination of the outbreak of extensively drug-resistant Shigella sonnei.

12 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Study finds mobile antibiotic resistance genes in some probiotic bacteria, raising concerns for public health

Researchers examine antibiotic resistance genes and their mobility in Bifidobacteriales and Lactobacillales species.

11 Apr 2023

Cornell receives $9.5 million NIH grant for chronic fatigue research

A Cornell multidisciplinary research center that studies chronic fatigue syndrome has received a five-year, $9.5 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Disease – funding that will enable experts from disparate fields to work together on the mysterious and debilitating condition.

11 Apr 2023

Exploring the tantalizing questions about sleep

Sleep is one of the most essential human activities - so essential, in fact, that if we don't get enough sleep for even one night, we may struggle to think, react, and otherwise make it through the day.

11 Apr 2023

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options.

11 Apr 2023

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

In Brazil, a group of researchers supported by FAPESP created mutant forms of Salmonella to understand the mechanisms that favor colonization of the intestinal tract of chickens by these pathogenic bacteria and find better ways to combat the infection they cause.

11 Apr 2023

Study to measure the impact of whole genome sequencing in patients with cardiovascular disease

Henry Ford Health research teams are launching a series of clinical studies in partnership with Illumina Inc., a global leader in DNA sequencing and array-based technologies, to assess the impact of comprehensive genomic testing in various disease areas.

11 Apr 2023

Dietary supplement N-acetylcysteine helps overcome treatment resistance in breast cancer

Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medication.

11 Apr 2023

Study expands the knowledge about gut viral diversity in healthy infants

Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.

11 Apr 2023

SARS-CoV-2 may exploit multiple receptors and pathways across various tissues, age groups

A study led by Mount Sinai researchers Dr. Bin Zhang, the Willard T.C. Johnson Research Professor of Neurogenetics, and Dr. Christian Forst, an Associate Professor in the Department of Genetics and Genomic Sciences, have identified potential novel receptors for SARS-CoV-2 and unveiled their tissue-specific and age-dependent expression.

11 Apr 2023

Discovery could pave the way for new approaches to treating chronic respiratory diseases

An international research team has discovered a new cell state in embryonic airway development that has been overlooked until now.

11 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Urban light pollution may disrupt winter dormancy period for disease-carrying mosquitoes

A new study's finding that urban light pollution may disrupt the winter dormancy period for mosquitoes that transmit West Nile virus could be considered both good news and bad news.

10 Apr 2023

Using the gene-editing tool to model certain liver tumor subtypes

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex.

10 Apr 2023

Study identifies four different autism subtypes based on brain activity and behavior

People with autism spectrum disorder can be classified into four distinct subtypes based on their brain activity and behavior, according to a study from Weill Cornell Medicine investigators.

7 Apr 2023

New finding in roundworms upends classical thinking about animal cell differentiation

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

7 Apr 2023

Genetic discovery may pave the way for precision medicine approaches to treat depression

A team of scientists at the Medical University of South Carolina (MUSC) has identified a stress-regulated gene that plays a role in the link between long-term stress and a common type of depressive behavior in mice.

7 Apr 2023

Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK

Study explores the emerging invasive group A Streptococcus M1uk lineage,

7 Apr 2023

Genes News and Research

Transcription of genes is fast but sloppy in old age

The international spread of drug-resistant Shigella sonnei

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Study finds mobile antibiotic resistance genes in some probiotic bacteria, raising concerns for public health

Cornell receives $9.5 million NIH grant for chronic fatigue research

Exploring the tantalizing questions about sleep

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

Study to measure the impact of whole genome sequencing in patients with cardiovascular disease

Dietary supplement N-acetylcysteine helps overcome treatment resistance in breast cancer

Study expands the knowledge about gut viral diversity in healthy infants

SARS-CoV-2 may exploit multiple receptors and pathways across various tissues, age groups

Discovery could pave the way for new approaches to treating chronic respiratory diseases

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Urban light pollution may disrupt winter dormancy period for disease-carrying mosquitoes

Using the gene-editing tool to model certain liver tumor subtypes

Study identifies four different autism subtypes based on brain activity and behavior

New finding in roundworms upends classical thinking about animal cell differentiation

Genetic discovery may pave the way for precision medicine approaches to treat depression

Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK

eBook: Using iPSCs models for human disease research and drug discovery eBook

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