Microscopy News and Research

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Nano-microscopy reveals collective transport of gold atoms in real-time

Researchers at Delft University of Technology used a High Resolution Electron Microscope to observe in real-time the collective transportation of gold atoms in a thin layer.

5 Feb 2007

Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus

The layers of mucus that protect sensitive tissue throughout the body have an undesirable side effect: they can also keep helpful medications away.

5 Feb 2007

Scientists tackle huntingtin protein

McMaster scientists are very close to defining small molecule drugs that should be able to redirect the huntingtin protein from accumulating in the wrong place within brain cells, which could potentially translate to a therapy for Huntington's Disease (HD).

29 Jan 2007

Nanocarrier stimuli-activated gene delivery

One approach to developing tumor-specific drug delivery agents is to create nanomaterials that release a therapeutic payload only after reaching their intended target.

29 Jan 2007

Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes

Researchers open the way for improved study of hepatitis C virus by devising a novel virus culture system that allows replication of patient-isolated virus in nontransformed hepatocytes, instead of culture-adapted virus strains in transformed cell lines.

23 Jan 2007

New understanding of the hit-and-run tactics used by infectious bacteria

New research from scientists at the University of Cambridge has the potential to radically change our understanding of how infection spreads around the body and improve the methods used to control it.

22 Jan 2007

Nanoscale "egg" to deliver platinum to tumor cells

Researchers at the Hong Kong University of Science and Technology have developed a nanoscale "egg" that could safely deliver platinum, a known anticancer agent, to tumor cells.

22 Jan 2007

Simple diagnostic test detects genetic signs of lung cancer in sputum

DNA coughed up along with phlegm could point to lung cancer, say researchers at the University of Maryland School of Medicine who are developing an inexpensive and non-invasive gene probe to help diagnose early stage lung cancer in current and former smokers.

18 Jan 2007

Physical testing of coatings on medical devices and medical tubing

For over 25 years CSMA have provided analytical solutions to the medical device sector.

16 Jan 2007

Nanoparticles yield delivery tools for therapeutic nucleic acids

Cancer researchers hold great hope that nucleic acid-based therapeutics, such as anticancer genes, antisense oligonucleotides, and small interfering RNA (siRNA) molecules, will prove to be powerful antitumor agents.

16 Jan 2007

Fibrinogen molecule structure acts as a molecular spring

Researchers at the University of Pennsylvania School of Medicine and the School of Arts and Sciences have shown that a well-known protein structure acts as a molecular spring, explaining one way that clots may stretch and bend under such physical stresses as blood flow.

14 Jan 2007

Cartilage discovery offers arthritis hope

Scientists have revealed the intricate structure of cartilage in what they hope will provide clues to how the crippling joint disease osteoarthritis might one day be treated.

From The University of Manchester 10 Jan 2007

Scientists visualize influenza virus particles

Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), and colleagues at the University of Virginia in Charlottesville have succeeded in imaging, in unprecedented detail, the virus that causes influenza.

2 Jan 2007

In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles

In an attempt to determine what factors make one nanoparticle better than another at targeting tumors, a team of investigators in Korea have conducted a systematic tumor-targeting study of a variety of self-assembling nanoparticles.

18 Dec 2006

New X-ray microscope shows nanomaterials in 3D

Using a new x-ray microscope that can look at nanomaterials in three dimensions, an international research team has produced the first detailed atomic structure of a core-shell nanoparticle.

18 Dec 2006

Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma

Nanoscale, inorganic fluorescent imaging agents such as quantum dots have become an important tool for researchers studying key biomolecules involved in cancer.

18 Dec 2006

FeCo/graphitic-shell nanocrystals as advanced magnetic-resonance-imaging and near-infrared agents

Alloys of iron and cobalt generate powerful magnetic signals that could be useful in nanoparticles designed to detect tumors using magnetic resonance imaging (MRI).

18 Dec 2006

Medium-sized polyps yield significant number of advanced adenomas and cancer

According to a University of Pittsburgh-led study published in the December issue of Gastroenterology, medium-sized polyps found in the colon with flexible sigmoidoscopy and subsequently evaluated by full colonoscopy are associated with a significant number of advanced adenomas (high-risk polyps) and cancers.

2 Dec 2006

Nanotechnology continues to advance anticancer gene therapy

Given that cancer is a disease in which genetic errors play a major role, it should come as no surprise that many experts envision a time when gene therapy will play an equally important role in the treatment of cancer.

20 Nov 2006

Watching a tumor cell migrate

Using a microfluidics device designed to reproduce the physical microenvironment of small blood vessels and the spaces between cells, researchers at the National University of Singapore have imaged single tumor cells deforming as they migrate through the device.

20 Nov 2006