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Researchers report how sildenafil can alleviate heart problems

How sildenafil, the active ingredient in Viagra, can alleviate heart problems is reported by Bochum's researchers in cooperation with colleagues from the Mayo Clinic in Rochester (Minnesota) in the journal Circulation.

23 Dec 2011

Roundup: HIV staff to be cut in Ga.; Abortion news in N.J., Mo.; Wis. Medicaid coverage in limbo

A loss of $3.7 million in federal funds is forcing Georgia to reduce its workforce for HIV prevention. After an inquiry by Georgia Health News, the Department of Public Health this week acknowledged that 20 people in state health districts have been notified they will probably lose their jobs in January, and that an unspecified number of staffers at the department level have received the same notification.

23 Dec 2011

MindFrame establishes ischemic stroke Registry

MindFrame Inc. today announces the establishment of an ischemic stroke Registry that will collect real-world clinical and procedural data through a secure web-based portal accessible only to registered clinician members.

23 Dec 2011

Declined consent affects organ donation rates

Research published today in the British Journal of Anaesthesia suggests that organ donation rates in the UK could be increased if the current issues affecting declined consent are improved. At present, only 30% of the UK population are registered on the NHS Organ Donor Register (ODR). From 2003 to 2005, the overall consent rate for donation after brain death (DBD) was 59%.

23 Dec 2011

Researchers discover key interaction at heart of promising new treatment for Fabry disease

A research team led by biochemist Scott Garman at the University of Massachusetts Amherst has discovered a key interaction at the heart of a promising new treatment for a rare childhood metabolic disorder known as Fabry disease.

23 Dec 2011

Correcting anemia can preserve kidney function in many transplant recipients

Correcting anemia, a red blood cell deficiency, can preserve kidney function in many kidney transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

23 Dec 2011

Researchers successfully treat severe congenital disorder in mouse model

Using a mouse model, Heidelberg University Hospital researchers have for the first time successfully treated a severe congenital disorder in which sugar metabolism is disturbed.

23 Dec 2011

Researchers present results from 31 major studies of blood-related cancers at ASH 2011 meeting

Researchers from the John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 best hospitals for cancer, presented results from 31 major studies of blood-related cancers - leukemia, lymphoma and multiple myeloma -- during the American Society of Hematology (ASH) Annual Meeting, December 10-13, 2011 in San Diego.

23 Dec 2011

Abbott commences Esprit drug eluting BVS trial in peripheral artery disease

Abbott today announced the initiation of ESPRIT I, a first-of-its-kind clinical trial in Europe evaluating the safety and performance of the novel Esprit drug eluting bioresorbable vascular scaffold (BVS) for the treatment of blockages in the superficial femoral arteries (SFA) and iliac arteries that have resulted in claudication.

23 Dec 2011

Researchers identify previously unknown gene fusion event in lung cancer

Smoking is a well-known risk factor for lung cancer, but nearly 25% of all lung cancer patients have never smoked. In a study published online today in Genome Research, researchers have identified a previously unknown gene fusion event that could explain a significant proportion of lung cancer cases in never-smokers, and might serve as a target for new therapies.

23 Dec 2011

ECMC network receives £35M grants for cancer medicine research

The Experimental Cancer Medicine Centres (ECMC) network, which runs UK clinical studies of the newest cancer treatments, has been awarded a second wave of £35M funding for the next five years.

23 Dec 2011

Longer looks: Manufacturing killer flu; The ironies of the individual mandate; When the elderly refuse help

In experiments conducted at the University of Wisconsin in Madison and Erasmus University in Rotterdam, the Netherlands, researchers engineered a strain of H5N1. … The next logical step would be for the researchers to publish studies in major scientific journals, describing the newly created flu, including its genetic makeup.

23 Dec 2011

D12-PGJ3 compound can cure leukemia

A compound produced from fish oil that appears to target leukemia stem cells could lead to a cure for the disease, according to Penn State researchers. The compound -- delta-12-protaglandin J3, or D12-PGJ3 -- targeted and killed the stem cells of chronic myelogenous leukemia, or CML, in mice, said Sandeep Prabhu, associate professor of immunology and molecular toxicology in the Department of Veterinary and Medical Sciences.

23 Dec 2011

Lean beef can contribute to heart-healthy diet

Lean beef can contribute to a heart-healthy diet in the same way lean white meats can, according to nutritional scientists.

22 Dec 2011

Effects of allopregnanolone in women with severe pre-menstrual syndrome

Sensitivity to allopregnanolone, a hormone that occurs naturally in the body after ovulation and during pregnancy, changes during the course of the menstrual cycle and is different in women with severe pre-menstrual syndrome (PMS) compared with women without PMS complaints. This has been shown by Erika Timby in her doctoral dissertation recently defended at Umeå University, Sweden.

22 Dec 2011

Study identifies six risk factors associated with blindness after spine surgery

A study published in the January 2012 issue of Anesthesiology identified six risk factors associated with blindness or partial blindness that can occur after major spine surgery: 1) male sex, 2) obesity, 3) use of a surgical frame that places the head lower than the heart, 4) length of the surgery, 5) amount of blood loss and 6) use of certain fluids that replace lost blood.

22 Dec 2011

FLT-PET imaging can effectively detect mantle cell lymphoma

Positron emission tomography (PET) and a molecular imaging agent that captures the proliferation of cancer cells could prove to be a valuable method for imaging a form of Non-Hodgkin's disease called mantle cell lymphoma, a relatively rare and devastating blood cancer.

22 Dec 2011

Gottlieb specialist, NWCR offer top weight-loss tips

Losing weight and saving money are the top New Year's resolutions expected to challenge Americans this year, experts say.

22 Dec 2011

Tips to keep your heart happy and healthy during holiday season

'Tis the season to be jolly and heart healthy. "It is common for us to see an increase in heart-related issues, particularly around Christmas and New Year's," said Brandon Stacey, M.D., a cardiologist at Wake Forest Baptist Medical Center. "It is important to know that if you experience any chest pain or discomfort, seek immediate medical attention or call 911."

22 Dec 2011

Scientists discover N-cadherin as promising therapeutic target for pancreatic cancer

Often, and without much warning, pancreatic cancer cells slip through the endothelial cells, head into the blood and out to other parts of the body to metastasize, making it one of the deadliest and hardest to treat cancers today.

22 Dec 2011