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Researchers suggest new key to switch off signaling pathways that lead to hypertension

A team of University of California, San Diego researchers has designed new compounds that mimic those naturally used by the body to regulate blood pressure. The most promising of them may literally be the key to controlling hypertension, switching off the signaling pathways that lead to the deadly condition.

23 Jul 2013

Results of post-mortem brain tissue study using Navidea's NAV4694 imaging agent presented at AAIC 2013

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that researchers at McGill Center for Studies in Aging, Douglas Research Institute and Montreal Neurological Institute presented results of a post-mortem brain tissue study using Navidea's investigational Fluorine-18 labeled β-amyloid imaging agent, NAV4694, during the Alzheimer's Association International Conference in Boston, MA.

23 Jul 2013

Resveratrol counteracts exercise benefits in older men

In older men, a natural antioxidant compound found in red grapes and other plants -- called resveratrol -- blocks many of the cardiovascular benefits of exercise, according to research published today [22 July 2013] in The Journal of Physiology.

22 Jul 2013

Study sheds light on how cells regenerate protective sheaths around nerve fibres in the brain

Multiple sclerosis treatments that repair damage to the brain could be developed thanks to new research.

22 Jul 2013

Researchers visualize live cell-to-cell communication pathways in bacteria

Most bacteria are able to communicate with each other by secreting signaling molecules. Once the concentration of signals has reached a critical density (-the Quorum), the bacteria are able to coordinate their behavior

20 Jul 2013

Study leads to new approach for treatment of aortic valve stenosis

A study conducted by the team of Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute, has led to the discovery of a new approach to treat aortic valve stenosis through the administration of a compound that prevents valve deterioration and can even reverse the progression of the disease.

19 Jul 2013

Idera Pharmaceuticals receives patent related to IMO-8400

Idera Pharmaceuticals, Inc. today announced that the United States Patent and Trademark Office has issued to Idera patent number 8,486,908, providing both composition of matter and method of use protection for IMO-8400.

19 Jul 2013

Bausch + Lomb obtains option to license MIM-D3 for treatment of dry eye syndrome

Bausch + Lomb, the global eye health company, and Mimetogen Pharmaceuticals Inc. today announced that Bausch + Lomb has acquired an option to license an investigational compound currently in Phase 2 development for the treatment of dry eye syndrome, a condition that affects millions of people worldwide.

19 Jul 2013

Penn researchers determine link between personality types and hot-spice preferences

Certain aspects of an individual's personality may be a determining factor in whether they like their food plain and bland or spicy and hot, according to research presented at the 2013 Institute of Food Technologists (IFT) Annual Meeting & Food Expo-.

18 Jul 2013

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

Thanks to a new $2 million investment, a drug that spurs cancer cells to self-destruct while sparing healthy cells is on the road to human clinical trials. The compound, known as PAC-1, has so far proven safe and has promising anti-cancer effects in cell culture, in mouse models of cancer and in pet dogs with spontaneously occurring lymphomas and osteosarcomas.

18 Jul 2013

Modified forms of bisphenol A found to alter hormone signaling in new, disturbing ways

For years, scientists have been worried about bisphenol A. The chemical is known as an "endocrine disruptor," a substance that interferes with the body's hormone signaling system, and it's found in everything from plastic drink bottles to the linings of food and drink cans to the thermal paper used for cash register receipts - not to mention the urine of 92.6 percent of Americans over the age of six.

18 Jul 2013

Chemical compound from ocean microbe offers potential treatments for anthrax

A team led by William Fenical at Scripps Institution of Oceanography at UC San Diego has discovered a new chemical compound from an ocean microbe in a preliminary research finding that could one day set the stage for new treatments for anthrax and other ailments such as methicillin-resistant Staphylococcus aureus (MRSA).

18 Jul 2013

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

We classified ‘long-term’ cannabis use as being regular, at least weekly, cannabis use for over 12 months. This is the period of time that’s used in the DSM-IV psychiatric diagnostic manual to classify substance use disorders. In our study the average duration of at least weekly use was just over four and a half years.

17 Jul 2013

Drug to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy

A drug already approved to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy, or thickening of the cardiac muscle--a disorder that often leads to heart failure, researchers at the University of Illinois at Chicago College of Medicine report.

17 Jul 2013

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

As surgeons who take care of cancer patients, we have observed a troubling association between patients who suffer from infections after surgery and the rapid spread of their cancer. We have reported this in lung cancer patients, and others have made these observations in a variety of different cancers. However, the mechanisms responsible for this association are still poorly understood.

16 Jul 2013

Accumulation of plaques in brain may serve as powerful biomarker for early detection of cognitive decline

The trajectory of amyloid plaque buildup-clumps of abnormal proteins in the brain linked to Alzheimer's disease-may serve as a more powerful biomarker for early detection of cognitive decline rather than using the total amount to gauge risk, researchers from Penn Medicine's Department of Radiology suggest in a new study published online July 15 in Neurobiology of Aging.

16 Jul 2013

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Columbia University Medical Center (CUMC) researchers are developing a new approach to cancer clinical trials, in which therapies are designed and tested one patient at a time.

16 Jul 2013

Study shows flavonoid-based nutritional supplements can affect endocrine system

Plant-based diets are healthy. Plants are high in flavonoids. So flavonoids are healthy. At least that's the reasoning of many manufacturers of flavonoid-based nutritional supplements.

16 Jul 2013

Protein complex may be an effective alternative to opioid pain medications

A drug targeting a protein complex containing two different types of opioid receptors may be an effective alternative to morphine and other opioid pain medications, without any of the side effects or risk of dependence, according to research led by the Icahn School of Medicine at Mount Sinai.

16 Jul 2013

Coffee and appetite: an interview with Matt Schubert and Associate Professor Ben Desbrow, Griffith University

We wanted to do something a bit different than the “typical” work on caffeine and exercise, and I have considerable interest in appetite regulation, so we built up from there.

15 Jul 2013

Compound News and Research

Researchers suggest new key to switch off signaling pathways that lead to hypertension

Results of post-mortem brain tissue study using Navidea's NAV4694 imaging agent presented at AAIC 2013

Resveratrol counteracts exercise benefits in older men

Study sheds light on how cells regenerate protective sheaths around nerve fibres in the brain

Researchers visualize live cell-to-cell communication pathways in bacteria

Study leads to new approach for treatment of aortic valve stenosis

Idera Pharmaceuticals receives patent related to IMO-8400

Bausch + Lomb obtains option to license MIM-D3 for treatment of dry eye syndrome

Penn researchers determine link between personality types and hot-spice preferences

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

Modified forms of bisphenol A found to alter hormone signaling in new, disturbing ways

Chemical compound from ocean microbe offers potential treatments for anthrax

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

Drug to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

Accumulation of plaques in brain may serve as powerful biomarker for early detection of cognitive decline

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Study shows flavonoid-based nutritional supplements can affect endocrine system

Protein complex may be an effective alternative to opioid pain medications

Coffee and appetite: an interview with Matt Schubert and Associate Professor Ben Desbrow, Griffith University

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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