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Effect of hydrocortisone treatment modality on glycemic control in patients with septic shock

Changing how critically ill patients are treated with hydrocortisone could reduce hyperglycemia.

18 Feb 2007

HIV protein TAT used to pull protein Bim into cancer cells - helps kill cancer cells

Cancer cells are sick, but they keep growing because they don't react to internal signals urging them to die. Now researchers at Washington University School of Medicine in St. Louis have found an efficient way to get a messenger into cancer cells that forces them to respond to death signals. And they did it using one of the most sinister pathogens around - HIV.

15 Feb 2007

Drug montelukast reduces trips to doctor for childhood asthma attacks

Young children with attacks of sporadic, recurring asthma who were treated with the prescription drug montelukast by their parents had fewer unscheduled trips to the doctor, missed less days from school or childcare, and caused their parents to take fewer days off work for their care.

15 Feb 2007

New ANS spinal cord stimulation lead for patients with low back pain

St. Jude Medical, Inc. has announced U.S. Food and Drug Administration (FDA) clearance of two spinal cord stimulation tripolar paddle leads for use with the Renew Neurostimulation System.

15 Feb 2007

Mechanism driving iron overload in thalassemia identified

Led by researchers at Weill Cornell Medical College in New York City, an international group of scientists has pinpointed a specific genetic relationship as the cause of dangerous iron overload in persons with a form of the inherited blood disease, beta-thalassemia.

14 Feb 2007

New oral blood thinner

A new oral blood thinner is being compared to an old standby to see if it works as well and is easier to manage long term, researchers say.

13 Feb 2007

New breast cancer drug Exemestane shows great potential to save lives

In what will be welcome news to millions of women suffering from breast cancer, trials of a new drug have found it lowers oestrogen levels in women with hormone-sensitive breast cancer and has the potential to save more than 1,000 lives a year in the UK alone.

13 Feb 2007

Maraviroc to receive accelerated review in U.S. and Europe

Pfizer announced today that marketing authorization applications for maraviroc will receive accelerated review in both the United States and Europe. Accelerated reviews are granted to potential medicines that, if approved, would represent significant improvements over current therapies.

13 Feb 2007

Breast cancer survival rates improved by novel drug sequence

Changing the way women are treated for breast cancer could improve their overall chance of survival, according to research published in the Lancet.

13 Feb 2007

Researchers discover how to fight iron disorders with a drug against hypertension

We all know that iron deficiencies are dangerous, but also too much iron is bad for our health. Our body stores excess iron in various tissues, where it can lead to organ failure and even death if not treated before irreversible damage has occurred.

12 Feb 2007

Robotic physiotherapist could treat patients and cut waiting times

A robotic system to treat physiotherapy patients with lower limb problems could lead to a decrease in waiting lists and the ability for patients to be treated outside of clinics.

From Sheffield Hallam University 12 Feb 2007

New technologies boost production of malaria drug artemisinin

New technologies that make the large-scale extraction of a natural antimalarial ‘wonder drug' both cheaper and greener are to be developed and trialled in a new European effort.

12 Feb 2007

Natural gum improves gold nanoparticles for cancer imaging

Gold nanoparticles have shown significant promise as agents to detect and treat cancer, but researchers have had difficulty creating gold nanoparticles that have suitable pharmacological properties for use in humans.

12 Feb 2007

Cancer breakthrough - first treatment to directly target tumor supply

For the first time, physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City have demonstrated in patients the ability of an antibody to directly target the blood supply of a wide variety of tumors, leaving healthy tissues unharmed.

12 Feb 2007

Combination drug treatment helps beat mesothelioma

People with mesothelioma - a form of cancer associated with asbestos exposure - have a higher survival rate when treated with a combination of two cancer drugs, a large multicenter study finds.

12 Feb 2007

Determinants of disease presentation and outcome during cryptococcosis

CRNS and the Institut Pasteur conducted research in France on patients diagnosed with cryptococcosis which ranks second among fatal opportunistic infections in patients infected by HIV and who are profoundly immunosuppressed.

12 Feb 2007

Vaccine against group B Streptococci

The search for a vaccine against group B streptococci Group B streptococci are one of the leading causes of infection in newborn infants, causing pneumonia, septicaemia or meningitis.

12 Feb 2007

Switching to an aromatase inhibitor provides mortality benefit in early breast carcinoma

For breast cancer patients taking tamoxifen, switching to an aromatase inhibitor within three years significantly improves survival rates, according to a new study.

12 Feb 2007

Changes in breast cancer management

Aggressive research currently underway brings hope of dramatic advances in breast cancer management, according to a new review.

12 Feb 2007

Rate of stem cell transplants among African-Americans lower

Lower transplant rates in ethnic communities may be explained somewhat by a lack of suitable anonymous donors, a problem the medical community has long known and been working to address. Surprisingly, the study found the discrepancy in treatment held true even when the transplant was autologous (e.g. self-donated stem cells were used) or when the cells were donated by a relative, typically a sibling.

11 Feb 2007