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Effect of physical activities on knee osteoarthritis in older adults

Regular exercise is recommended for middle-aged and older people, but the effect of exercise on the development of osteoarthritis (OA) in older people is unclear, especially if they are overweight.

31 Jan 2007

Statins slow the progression of aortic valve stenosis

The trial provides the first prospective clinical evidence that aortic valves have an active biology that can be targeted with medical therapy and contradicts research published in 2005 in the New England Journal of Medicine, which concluded statins did not halt the progression of aortic stenosis.

30 Jan 2007

Psychological effects of heart surgery

Cases of congenital heart disease (CHD), in both adolescents and adults, have been on the rise for many years.

30 Jan 2007

Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women

Aromatase inhibitors, a type of hormone therapy used to treat advanced breast cancer in postmenopausal women, result in a small but significant increase in overall survival when compared to other hormone treatments, according to a new systematic review of studies.

30 Jan 2007

A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis

Marked by chronic inflammation of the joints and tissue, rheumatoid arthritis (RA) is a painful and potentially disabling autoimmune disease.

30 Jan 2007

Merck Serono launches growth hormone injection device

Merck Serono has announced the launch of a unique growth hormone injection device, easypod, for the once-daily administration of Saizen (somatropin), the company's recombinant growth hormone deficiency therapy. easypod is the first of its kind in this therapeutic area and was designed to improve patients' ease of daily use, reliability and convenience.

30 Jan 2007

Drug giant Wyeth loses another HRT trial to the tune of $1.5 million

Drug giant Wyeth has been ordered by a court in Philadelphia to pay $1 million in compensation to a woman who developed breast cancer after taking the hormone replacement therapy (HRT) Prempro.

30 Jan 2007

Stroke treatment helps victims recover brain function

A small but significant study in the U.S. has found that a treatment which was designed to clear blocked carotid arteries and prevent stroke has also improved brain function.

29 Jan 2007

New testing approach to predict outcome in patients with bladder cancer

A new testing approach has been shown to be effective in identifying patients at the highest risk of cancer relapse after surgery for bladder cancer, say researchers in the February issue of The Lancet Oncology.

29 Jan 2007

Time, therapy spur recovery from sudden sensorineural hearing loss

A first-of-its-kind study into time-dependent treatments of sudden sensorineural hearing loss published in the February 2007 issue of Otolaryngology- Head and Neck Surgery has determined that a combination of time and oral corticosteroid therapy can play a key role in helping patients regain full hearing, often within a month of the initial loss of hearing.

29 Jan 2007

Scientists tackle huntingtin protein

McMaster scientists are very close to defining small molecule drugs that should be able to redirect the huntingtin protein from accumulating in the wrong place within brain cells, which could potentially translate to a therapy for Huntington's Disease (HD).

29 Jan 2007

Number of Parkinson's sufferers will double in next 25 years

The study highlights the significant challenge facing countries with rapidly growing economies, particularly in Asia, many of which are ill prepared to meet this impending public health threat.

29 Jan 2007

Dll4 signalling through Notchi regulates formation of tip cells during angiogenesis

All tissues, sick and healthy alike, need a blood supply to survive and grow. The key to many medical problems, like preventing tumour development, is therefore to obstruct the spread of the blood vessels. Research scientists at Karolinska Institutet have now discovered a heretofore unknown mechanism for how the body links together its blood vessels.

29 Jan 2007

New drug to treat kidney failure during septic shock

Research from Melbourne's Howard Florey Institute and the Austin Hospital has resulted in a drug to treat kidney failure during septic shock, which will be trialled at the Austin Hospital from mid-2007.

29 Jan 2007

North American Menopause Society releases guidelines saying HRT beneficial for younger women

The North American Menopause Society on Thursday released a revised position statement that said the benefits of short-term hormone replacement therapy for treatment of menopausal women likely outweigh the risks for younger women, the Wall Street Journal reports.

28 Jan 2007

Advocates should focus on long-term strategy to fight HIV/AIDS

HIV/AIDS advocates should focus on developing a long-term strategy for the fight against the pandemic, Global Fund To Fight AIDS, Tuberculosis and Malaria Executive Director Richard Feachem said on Wednesday during a satellite meeting at the World Economic Forum in Davos, Switzerland, Reuters Health reports.

28 Jan 2007

New tool to detect depression in cancer patients

A tool to detect depression in cancer patients launched by the University of Liverpool will vastly improve patients' ability to come to terms with their disease.

28 Jan 2007

Linemen more than twice as likely as other players to have metabolic syndrome

After retirement, National Football League (NFL) linemen - generally the heaviest players - are more than twice as likely as other players to have a syndrome that puts them at risk for heart disease, stroke and other cardiovascular diseases

28 Jan 2007

Small molecule targets weak mRNA

A new strategy for fighting cancer aims to make its genes get lost in translation, according to a report in the January 26, 2007, issue of the journal Cell.

28 Jan 2007

Link between MRI contrast agent and nephrogenic systemic fibrosis

New research has shown a possible association between a popular magnetic resonance imaging (MRI) contrast agent and the incidence of a rare disease called nephrogenic systemic fibrosis (NSF) in patients with kidney disease, according to an editorial appearing in the March issue of Radiology.

28 Jan 2007