Genes News and Research

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Endothelial deletion of the Wt1 gene affects coronary vessel formation and myocardial development

How is the mammals' heart formed? What role do endothelial cells play? Do the same pathways and genes involved in the formation of the embryonic heart also play a role in repair processes?

4 Apr 2023

Increased expression of collagens can drive longer lifespan at warm temperatures

Researchers have long known that many animals live longer in colder climates than in warmer climates.

4 Apr 2023

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

Researchers assessed the cellular and molecular level immunopathology of PCLD.

4 Apr 2023

Study elucidates the genetics of preterm birth and pregnancy length

New knowledge of the genetic factors behind premature delivery and gestational duration has now emerged.

3 Apr 2023

BU researcher wins $3.9 million NIH grant to develop novel therapeutic modalities for Alzheimer's

Julia TCW, PhD, assistant professor of pharmacology & experimental therapeutics at Boston University Chobanian & Avedisian School of Medicine, has received a five-year, $3.9 million grant from the National Institutes of Health's National Institute on Aging.

3 Apr 2023

VTC professor awarded NIH grant to study a potential therapy for DiGeorge syndrome

The human brain begins to assemble itself shortly after conception as a growing number of brain cells connect to create circuits across the brain.

3 Apr 2023

Yale-led team creates new resource that is an important step toward personalized care

Each person has about 4 million sequence differences in their genome relative to the reference human genome.

3 Apr 2023

Cold temperature plays a central role in longevity

Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging.

3 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Researchers reviewed existing literature on the benefits of adopting Mediterranean diets against inflammatory conditions and cancer.

3 Apr 2023

Transposable elements in various cancers could be used to harness novel immunotherapies

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don't typically respond to immune-based treatments. Shown is a 3D rendering of cancer cells.

31 Mar 2023

Researchers report surprising first steps that promote resistance to commonly prescribed antibiotics

Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide.

31 Mar 2023

Researchers develop new method to make rare cell types and disease patterns visible in tissue

The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision.

31 Mar 2023

Study shows a genetic association of diarrhea in children

Susceptibility to diarrhea, a major cause of infant deaths in low- and middle-income countries, has genetic links which could hold the key to new treatments, research suggests.

31 Mar 2023

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

Researchers investigated the feasibility of utilizing a bacterial contractile injection system for programmable protein delivery.

31 Mar 2023

Early life adversity linked to accelerated neurobiological aging, raising vulnerability to depression and Alzheimer's

scientists investigate the neurocognitive correlates of genetic vulnerability to major depressive disorder and Alzheimer's disease.

30 Mar 2023

New microscopy method illuminates the mechanics of embryo development

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon – when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging some energy in the process.

30 Mar 2023

Riboswitch may be the key to advance gene therapy, regenerative medicine

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

30 Mar 2023

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

30 Mar 2023

New research may upend long-held scientific dogma about short telomeres and cancer risk

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

30 Mar 2023

Genes News and Research

Endothelial deletion of the Wt1 gene affects coronary vessel formation and myocardial development

Increased expression of collagens can drive longer lifespan at warm temperatures

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

Study elucidates the genetics of preterm birth and pregnancy length

BU researcher wins $3.9 million NIH grant to develop novel therapeutic modalities for Alzheimer's

VTC professor awarded NIH grant to study a potential therapy for DiGeorge syndrome

Yale-led team creates new resource that is an important step toward personalized care

Cold temperature plays a central role in longevity

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Transposable elements in various cancers could be used to harness novel immunotherapies

Researchers report surprising first steps that promote resistance to commonly prescribed antibiotics

Researchers develop new method to make rare cell types and disease patterns visible in tissue

Study shows a genetic association of diarrhea in children

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

Early life adversity linked to accelerated neurobiological aging, raising vulnerability to depression and Alzheimer's

New microscopy method illuminates the mechanics of embryo development

Riboswitch may be the key to advance gene therapy, regenerative medicine

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

New research may upend long-held scientific dogma about short telomeres and cancer risk

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo