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The McLean Hospital Brain Bank receives new NIH contract

The Harvard Brain Tissue Resource Center at McLean Hospital, known as the Brain Bank, has received a new contract from the National Institutes of Health for a total of $12,796,394.

29 Oct 2019

Discovery in monkeys could pave way for treatment of Bardet-Biedl Syndrome

A genetic mutation that leads to a rare, but devastating blindness-causing syndrome has been discovered in monkeys for the first time. The finding offers a promising way to develop gene and cell therapies that could treat the condition in people.

25 Oct 2019

Nerve cell protection without side effects on erythropoiesis

The hormone erythropoietin (Epo) is a well-known doping substance that has a long history of abuse in endurance sports, such as cycling. In addition to promoting red blood cell production (erythropoiesis), which improves the oxygen supply in the organism, Epo also protects nerve cells from cell death.

25 Oct 2019

Neuroscientists identify how people can have a 'crash in visual processing'

Georgetown neuroscientists say they have identified how people can have a "crash in visual processing" - a bottleneck of feedforward and feedback signals that can cause us not to be consciously aware of stimuli that our brain recognized.

25 Oct 2019

Scientists uncover how brain cells respond to and recover from lack of nutrition

We all know that food is essential to healthy development of the brain and body, especially in the earliest stages of life. But exactly how early brain growth is affected by nutrition is not as well understood, especially on a cellular level.

25 Oct 2019

Insights about the sweet receptor could lead to better-tasting food

Whether it's chocolate cake or pasta sauce, the sensation of sweetness plays a major role in the human diet and the perception of other flavors.

24 Oct 2019

High-salt diet may trigger dementia

We’ve all heard that taking too much salt can damage your blood vessels, and now a new study published in the journal Nature on October 23, 2019, says it’s true – a diet rich in salt reduces the levels of nitric oxide, which in turn alters the tau protein within the neuron, triggering a fall in cognitive processing by the brain.

24 Oct 2019

Researchers identify potential approach to stop growth of common brain tumor in children

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children.

24 Oct 2019

Risk factors for unemployment with multiple sclerosis vary by age, study finds

A recent study by Kessler Foundation researchers explored numerous factors that contribute to the high unemployment rate among individuals of different ages with multiple sclerosis.

24 Oct 2019

Gulf War Illness and chronic fatigue syndrome are two very distinct diseases of the brain

Gulf War Illness (GWI) and chronic fatigue syndrome (CFS) share symptoms of disabling fatigue, pain, systemic hyperalgesia (tenderness), negative emotion, sleep and cognitive dysfunction that are made worse after mild exertion (postexertional malaise).

23 Oct 2019

Molecular processes underlying communication between gut microbes and brain cells revealed

New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine and Cornell's Ithaca campus.

23 Oct 2019

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson's and Alzheimer's diseases, and improves cognitive and motor behavior.

23 Oct 2019

MIT neuroscientists find a way to reverse noise hypersensitivity in mice

People with autism often experience hypersensitivity to noise and other sensory input. MIT neuroscientists have now identified two brain circuits that help tune out distracting sensory information, and they have found a way to reverse noise hypersensitivity in mice by boosting the activity of those circuits.

23 Oct 2019

New $30M contract signed to accelerate TB vaccine development across the country

Tuberculosis (TB) is the number-one cause of death from an infectious disease in the world: In 2017, the most recent data available, 10 million people developed TB and 1.6 million died.

23 Oct 2019

Discovery sheds light on TNFα protein's role in impairing memory in Alzheimer's disease

Otago scientists have made an important discovery in understanding the role a particular protein plays to impair memory in Alzheimer's disease, which could lead to more effective treatment in future.

23 Oct 2019

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

The National Institute on Drug Abuse, part of the National Institutes of Health, awarded a $3.58 million grant to Sanford Burnham Prebys scientist Anthony Pinkerton, Ph.D., to advance a potential treatment for opioid-use disorders, called SBI-553.

23 Oct 2019

Link between pregnancy stress, immune activation, and postpartum depression

A new study presented at the Society for Neuroscience meeting on October 19, 2019, at Chicago, shows for the first time how postpartum depression could actually be due to abnormal immune system activation within the brain, which in turn is set off by chronic pregnancy stress. This is the earliest study to show this link in animals.

22 Oct 2019

New study identifies gene that causes intellectual disability syndrome

It used to take several years or sometimes decades to unequivocally identify the genes that cause rare human syndromes that affect very few individuals. Nowadays, however, human geneticists and fly and mouse biologists have the means to work together to integrate their data, which has significantly accelerated the pace of disease and gene discovery.

22 Oct 2019

Researchers receive $3.2 million NIH grant to pursue a deeper understanding of Down syndrome

Mount Sinai researchers have been awarded a $3.2 million grant from the National Institutes of Health to pursue a deeper understanding of Down syndrome, the most common genetic cause of intellectual and developmental disabilities in children and young adults, affecting more than 200,000 individuals in the United States.

22 Oct 2019

Neural mechanism could help explain how the brain creates memories of episodes

The memory of specific episodes is the base of autobiographical memory, but we do not know how the brain structures the experience to remember it in the long run.

22 Oct 2019

Neuroscience News and Research

The McLean Hospital Brain Bank receives new NIH contract

Discovery in monkeys could pave way for treatment of Bardet-Biedl Syndrome

Nerve cell protection without side effects on erythropoiesis

Neuroscientists identify how people can have a 'crash in visual processing'

Scientists uncover how brain cells respond to and recover from lack of nutrition

Insights about the sweet receptor could lead to better-tasting food

High-salt diet may trigger dementia

Researchers identify potential approach to stop growth of common brain tumor in children

Risk factors for unemployment with multiple sclerosis vary by age, study finds

Gulf War Illness and chronic fatigue syndrome are two very distinct diseases of the brain

Molecular processes underlying communication between gut microbes and brain cells revealed

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

MIT neuroscientists find a way to reverse noise hypersensitivity in mice

New $30M contract signed to accelerate TB vaccine development across the country

Discovery sheds light on TNFα protein's role in impairing memory in Alzheimer's disease

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

Link between pregnancy stress, immune activation, and postpartum depression

New study identifies gene that causes intellectual disability syndrome

Researchers receive $3.2 million NIH grant to pursue a deeper understanding of Down syndrome

Neural mechanism could help explain how the brain creates memories of episodes

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