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Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

A study recently identified Neurolipin-1 or NRP1, a host factor for SARS-CoV-2 infection, as a cargo retrograde-transported by the ESCPE-1.

26 Jan 2022

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

In a new study, scientists have compared the Omicron variant with the Delta VOC (B.1.617.2) as well as the wildtype strain (B.1), with respect to their interaction with the antiviral type 1 interferon response in infected cells.

26 Jan 2022

Effects of the Omicron spike amino acid changes in the interaction with human ACE2 receptor or human antibodies

A recent study analyzed the effects of the interaction between SARS-CoV-2 Omicron spike amino acid and the human ACE2 receptor or with human antibodies.

26 Jan 2022

Research says spill-over of SARS-CoV-2 from humans to cattle is possible

In a recent study posted to the bioRxiv* preprint server, a team of researchers assessed the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from humans to cattle.

26 Jan 2022

Understanding immune responses to SARS-CoV-2 infections in children

A study published in the journal Immunity analyzed the varied manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children.

26 Jan 2022

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

In research recently published in the journal of Science Advances, an interdisciplinary team of researchers from the University of Chicago assessed the potential role of cannabidiol (CBD), a natural product extracted from the cannabis plant, to prevent and inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in human cells and mice.

26 Jan 2022

‘Lefty’ protein pumps the brakes during initial stages of embryo differentiation

A protein known as Lefty pumps the brakes as human embryos begin to differentiate into the bones, soft tissues and organs that make us.

25 Jan 2022

Third dose of BNT162b2 vaccine protects against Omicron hospitalizations

A new study assesses the effectiveness of two and three doses of the BNT162b2 vaccine against Omicron-related hospitalizations.

25 Jan 2022

Study examines the association of race and ethnicity with initiation of newer diabetes medications

Among patients with type 2 diabetes, minority racial/ethnic groups have higher rates of diabetes complications including cardiovascular disease, chronic kidney disease and hypoglycemia (low blood sugar).

25 Jan 2022

Spike-mediated CFTR inhibition accounts for airway inflammation in COVID-19

A new study looks at the molecular level inhibition of the protective CFTR gene by the SARS-CoV-2 spike protein.

25 Jan 2022

Development of synthetic molecules that can bridge T cells with SARS-CoV-2 infected cells

Scientists have recently used synthetic biology to design primary human CD8 T cells to express Spike protein-specific chimeric antigen receptors (ACE2 CAR or anti-Spike CAR).

25 Jan 2022

Broad and potent neutralizing activity of human IgG1 LALA antibody against SARS-CoV-2 variants

A new study has focused on the identification, in vitro binding, and potent neutralizing activity of STI-9167 (plutavimab) against live viruses and pseudotype viruses.

25 Jan 2022

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

A new study investigated SARS-CoV-2 spike protein responses targeted by cross-reactive T cells that were isolated from convalescent COVID-19 individuals along with previously uninfected donors.

25 Jan 2022

Sensitivity and specificity of a “spit and mail” SARS-CoV-2 serology test

A recent study evaluated the sensitivity and specificity of a “spit and mail” serology test.

25 Jan 2022

LA County study finds COVID-19 'herd immunity' unlikely

In a research letter published in the Journal of the American Medical Association (JAMA), researchers carried out a seroprevalence and vaccination coverage study in Los Angeles County (LAC).

24 Jan 2022

Current vaccines prompt the body to make effective, long-lasting T cells against SARS-CoV-2 variants

Scientists at La Jolla Institute for Immunology (LJI) have found that four COVID-19 vaccines (Pfizer-BioNTech, Moderna, J&J/Janssen, and Novavax) prompt the body to make effective, long-lasting T cells against SARS-CoV-2.

24 Jan 2022

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)."

24 Jan 2022

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

Antibody response 18 months after SARS-CoV-2 infection in vaccinated and unvaccinated individuals

A new study assessed the dynamics of IgG titers over 18 months in patients who had recovered from COVID-19 infections during March 2020.

24 Jan 2022

Alpaca-derived antibody fragment disrupts interaction between SARS-CoV-2 spike protein and human ACE2

Researchers have been investigating the potential for using nanobodies – special immune particles from llamas and alpacas – against the disease.

24 Jan 2022

Receptor News and Research

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

Effects of the Omicron spike amino acid changes in the interaction with human ACE2 receptor or human antibodies

Research says spill-over of SARS-CoV-2 from humans to cattle is possible

Understanding immune responses to SARS-CoV-2 infections in children

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

‘Lefty’ protein pumps the brakes during initial stages of embryo differentiation

Third dose of BNT162b2 vaccine protects against Omicron hospitalizations

Study examines the association of race and ethnicity with initiation of newer diabetes medications

Spike-mediated CFTR inhibition accounts for airway inflammation in COVID-19

Development of synthetic molecules that can bridge T cells with SARS-CoV-2 infected cells

Broad and potent neutralizing activity of human IgG1 LALA antibody against SARS-CoV-2 variants

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

Sensitivity and specificity of a “spit and mail” SARS-CoV-2 serology test

LA County study finds COVID-19 'herd immunity' unlikely

Current vaccines prompt the body to make effective, long-lasting T cells against SARS-CoV-2 variants

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

Antibody response 18 months after SARS-CoV-2 infection in vaccinated and unvaccinated individuals

Alpaca-derived antibody fragment disrupts interaction between SARS-CoV-2 spike protein and human ACE2

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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