Therapy News and Research

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Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients

A protein that activates estrogen receptors in breast cancer may play a role in resistance to therapeutic effects of anti-estrogen tamoxifen treatment, according to a study in the Journal of the National Cancer Institute.

17 May 2006

Effectiveness of radiation therapy for older women with early breast cancer

Elderly women with early-stage breast cancer had a lower risk of recurrence when they were treated with radiation therapy, according to a study in the Journal of the National Cancer Institute.

17 May 2006

Study calls for more consistent use of anti-clotting medications in women

High-risk women with acute coronary syndrome benefit as much as men from a trip to the cardiac cath lab shortly after being hospitalized, according to a study reported recently at the Society for Cardiovascular Angiography and Interventions (SCAI) 29th Annual Scientific Sessions in Chicago.

17 May 2006

Gene family of potential tumor inhibitors identified

Proteins from a newly discovered family of genes, LRIG, function as a retardant for a protein that is important to tumor cells. It is probably this mechanism that lends the gene family its inhibiting effect on cancer tumors.

17 May 2006

Study gives new insight into the stages of recovery of hand muscle control after a stroke

A Queen's study of stroke survivors gives new insight into the stages of recovery of hand muscle control after a stroke, suggesting that patients may benefit from different treatment strategies at different times during the recovery process.

17 May 2006

No link found between statins and breast cancer

According to a new study by U.S. researchers, women who use statin drugs to lower their cholesterol are no more likely to develop breast cancer than women who do not use the drugs.

17 May 2006

Critics say expert's figure of 350,000 Russians with HIV an underestimation

Russia is experiencing a burgeoning epidemic as HIV/AIDS continues to spread beyond the ranks of drug users, gay men and prostitutes, into the larger population.

16 May 2006

Malaria - the left hand doesn't know what the right hand is doing!

The World Health Organisation (WHO) is quite rightly patting itself on the back because it has persuaded as many as 13 drug companies to abandon the marketing and promotion of monotherapy in the treatment of Malaria.

16 May 2006

German scientists synthesize new compound that reduces stroke damage

A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms.

16 May 2006

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia

Long-term therapy with some antiepileptic drugs and antibiotics can cause osteomalacia, a condition marked by softening of the bones that is usually the result of vitamin D and calcium deficiency.

16 May 2006

Signaling pathways in immune cells may lead to novel HIV treatment

New research on signaling pathways in immune cells bolsters evidence of connections between the central nervous system and the immune system.

16 May 2006

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

Scientists have identified a new molecule that inhibits proliferation of a broad range of lethal malignant glioma cells in vitro and in vivo.

16 May 2006

A review of percutaneous kyphoplasty

A procedure that fills in fractured vertebrae with injected cement has not been shown to improve a person's back pain or quality of life, according to a new analysis of studies.

16 May 2006

First animal model that mimics human head and neck cancer

An Oregon Health & Science University Cancer Institute research laboratory has developed a novel mouse model designed specifically to study the often devastating head and neck squamous cell cancers.

16 May 2006

Full year of treatment with pyrimethamine and sulfadiazine helps infants and children with toxoplasmosis

The first long-term study shows that treatment with pyrimethamine and sulfadiazine (two anti-parasitic drugs) during the first year of life leads to a lasting reduction in brain and eye damage for children with congenital toxoplasmosis.

16 May 2006

Review identifies factors that influence patient treatment choice for localized prostate cancer

Variables that influence a patients' choice of treatment for localized prostate cancer (CaP) are identified in a literature review that is authored by Dr. Zeliadt and colleagues and appears in the on-line version of Cancer, 2006.

16 May 2006

A therapeutic method for failed bladder augmentation in children

This study by Vajda et al investigated the potential causes leading to the deterioration of a previously successful bladder augmentation. This study by Vajda et al investigated the potential causes leading to the deterioration of a previously successful bladder augmentation.

16 May 2006