Therapy News and Research

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Management of diabetic patients in a primary care setting can be improved by an intervention aimed at physicians

The intervention was individualized to each physician's record of action when patient glucose levels were high, and featured regular feedback on their performance.

15 Mar 2006

Therapy for slightly raised blood pressure delays hypertension

A new study shows by giving a blood pressure drug to people with measurements above normal but not yet considered too high, the development of hypertension might be delayed.

15 Mar 2006

Studying the gene-expression profiles of patients with colorectal cancer might help predict their response to chemotherapy

Studying the gene-expression profiles of patients with colorectal cancer might help predict their response to chemotherapy.

15 Mar 2006

Salt substitution in rural China would cut hypertension rates

A salt substitute specially formulated to be flavourful and effective has significantly reduced blood pressure among high-risk residents of northern, rural China, where home-pickled foods are a dietary mainstay and hypertension is rampant.

15 Mar 2006

Researchers evaluate efficacy, safety of anti-clotting drugs

Patients admitted to the hospital with an acute coronary syndrome (ACS) are often treated with a catheter-based procedure known as percutaneous coronary intervention, or PCI.

15 Mar 2006

Cells in mucus from lungs point to a unique screening method that could lead to earlier treatment of lung cancer

In a group of high-risk patients, a test that examined DNA from cells expelled in sputum for evidence of "silenced" genes correctly identified the majority of patients who were later diagnosed with lung cancer, say researchers in a study published in the March 15 issue of Cancer Research.

15 Mar 2006

Wearing a special mask to bed helps children with sleep apnea breathe and sleep better

Wearing a special mask to bed helps children with sleep apnea breathe and sleep better, but a small, six-month study at Johns Hopkins Children's Center and two other pediatric hospitals suggests children aren't always using them consistently enough to reap the maximum benefits.

15 Mar 2006

Impact of a scientific presentation on community treatment patterns for primary breast cancer

The oral presentation of data from a single study at a national scientific conference can have an important impact on patient treatment, even before study publication or Food and Drug Administration (FDA) approval

15 Mar 2006

The safety and effectiveness of fondaparinux for heart attacks

The results of a large international cardiovascular trial will shed light on whether the addition of a new drug that prevents blood clotting, or thrombosis, can improve the treatment of the most serious form of heart attacks.

15 Mar 2006

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Scientists gain better understanding of the behavior of leukemic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Cardiac resynchronization therapy devices during hospital stays linked to better outcomes

Placement of devices that synchronize the pumping chambers of the heart in patients while they're hospitalized for a congestive heart failure episode appears to lower patients' risk of death or rehospitalization during at least the next two to three months, new research suggests.

14 Mar 2006

Innovative treatment for critical limb ischemia

A new randomized study presented at the American College of Cardiology's 55th Annual Scientific Session investigates an innovative treatment for critical limb ischemia, or lack of arterial blood supply and oxygen to the legs, using a therapeutic approach to generate new blood vessels.

14 Mar 2006

Researchers find viable new sources for stem cell transplants to the heart

Stem cell transplantation is among one of the most exciting and hotly debated areas of medical research today. While the promise of personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field.

14 Mar 2006

Creative new therapies for atherosclerotic disease

Patients with a build-up of plaque in arteries in the heart, brain and leg face a high risk of major cardiovascular complications.

14 Mar 2006

Faxing alerts to physicians not enough to improve antidepressant adherence

"Our findings confirm that patient-specific alerts using faxes to physicians are not effective at improving patient adherence to antidepressant therapy in the absence of other complementary, coordinated interventions," said Bambauer.

14 Mar 2006

Valproic acid may help slow the progression of dementia

Researchers have found that a common anticonvulsant drug improved cognitive function and appeared to restore nerve cells in the brains of patients with HIV-related dementia. The results of the Phase I clinical trial are published in the March issue of the scientific journal Neurology.

14 Mar 2006

Clopidogrel reduces risk of adverse events for patients with acute coronary syndromes undergoing balloon angioplasty

Patients with acute coronary syndromes who were pre-treated with the anti-platelet agent clopidogrel before undergoing a procedure such as balloon angioplasty or stent placement had a reduced risk of adverse events if they received the anti-clotting drug abciximab

14 Mar 2006

Study recommends treatment change for pre-leukemia disease

A new study finds that longer courses of a mild form of chemotherapy may help patients with a bone marrow disease only recently considered a form of cancer.

14 Mar 2006

Decitabine improves myelodysplastic syndrome treatment

A potent member of a new class of drugs increases survival in some patients with myelodysplastic syndrome (MDS), and may become the new standard of therapy for this group of pre-cancer disorders

14 Mar 2006

Therapy News and Research

Management of diabetic patients in a primary care setting can be improved by an intervention aimed at physicians

Therapy for slightly raised blood pressure delays hypertension

Studying the gene-expression profiles of patients with colorectal cancer might help predict their response to chemotherapy

Salt substitution in rural China would cut hypertension rates

Researchers evaluate efficacy, safety of anti-clotting drugs

Cells in mucus from lungs point to a unique screening method that could lead to earlier treatment of lung cancer

Wearing a special mask to bed helps children with sleep apnea breathe and sleep better

Impact of a scientific presentation on community treatment patterns for primary breast cancer

The safety and effectiveness of fondaparinux for heart attacks

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells

Scientists gain better understanding of the behavior of leukemic cells

Cardiac resynchronization therapy devices during hospital stays linked to better outcomes

Innovative treatment for critical limb ischemia

Researchers find viable new sources for stem cell transplants to the heart

Creative new therapies for atherosclerotic disease

Faxing alerts to physicians not enough to improve antidepressant adherence

Valproic acid may help slow the progression of dementia

Clopidogrel reduces risk of adverse events for patients with acute coronary syndromes undergoing balloon angioplasty

Study recommends treatment change for pre-leukemia disease

Decitabine improves myelodysplastic syndrome treatment

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