Cell Metabolism News and Research

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Weight gain may be the result of inefficient fat metabolism

Researchers from the Karolinska Institutet have shown that protracted weight gain can, in some cases, be attributed to a reduced ability to metabolise fat.

31 May 2018

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

Anyone who's taken a bite of a sandwich with too much spicy mustard or a piece of sushi with too much wasabi can attest to the tear-inducing sensation these condiments can cause. These loud warnings to the nervous system of exposure to potentially harmful chemicals are triggered by TRPA1, a calcium channel protein sometimes referred to as the "wasabi receptor."

25 May 2018

New approach to study brown fat could aid in finding treatments for obesity

A new technique to study fat stores in the body could aid efforts to find treatments to tackle obesity.

25 May 2018

Researchers discover cascade of immune processes linked to poor outcomes in aggressive breast cancer

Cancer is crafty. To survive and thrive, tumors find a way of thwarting our body's natural systems.

24 May 2018

UCLA researchers characterize mechanism of mEAK-7 gene for the first time

For years, researchers have known that a gene called EAK-7 plays an important role in determining how long worms will live.

15 May 2018

Disease tolerance is the key to treating TB, say experts

A new study from McGill University suggests it is the body’s ability to “tolerate” rather than “resist” TB infection that stops symptoms of the disease developing.

14 May 2018

Increasingly failing communication between cells' organelles is main cause of aging, shows study

A basic discovery of how the cellular functions are connected to control aging is presented in the journal Cell Metabolism.

11 May 2018

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Kidney cancer, one of the ten most prevalent malignancies in the world, has increased in incidence over the last decade, likely due to rising obesity rates.

10 May 2018

Fat-controlling hormones increase metabolism in both exercise and cold

Sad but true, we don't all respond equally to exercise. Researchers at Joslin Diabetes Center have uncovered a new kind of clue to this variable response--a hormone whose levels in the bloodstream rise sharply in exercise as well as in cold.

2 May 2018

Roswell Park researchers identify driver of cancer-promoting metabolic changes

Roswell Park Comprehensive Cancer Center researchers have identified a potential key player promoting cancer progression through changes in the cell environment that are conducive to metastasis.

17 Apr 2018

Researchers find possible therapeutic strategy to block self-eating in pancreatic cancers

To get the extra energy they need to fuel their uncontrolled growth, cancer cells break down some of their own parts for fuel - a process known as autophagy, or "self-eating."

13 Apr 2018

Study reveals unexpected mechanism that induces thirst after alcohol or sugar exposure

Why does drinking alcohol or consuming sugar make us thirsty? An international study of mice in Texas and humans in Europe reveals an unexpected anti-dehydration mechanism.

12 Apr 2018

Finding new drug target for common form of lung cancer

Research by Rutgers Cancer Institute of New Jersey investigators has identified novel functions of the superoxide dismutase 1 (SOD1) enzyme providing support that it could serve as a therapeutic target in the most common type of lung cancer.

10 Apr 2018

Autofluorescence imaging evaluates cell metabolism and wound healing

Kyle Quinn, assistant professor of biomedical engineering at the University of Arkansas, has published a review highlighting recent advances in autofluorescence imaging and discussing its role in evaluating cell metabolism.

5 Apr 2018

Researchers discover how muscles regulate oxygen consumption

A new study by researchers from Karolinska Institutet shows that an enzyme called FIH determines how muscles consume oxygen. Without the enzyme, the need for oxygen increases during physical exercise. The finding is of potential significance to elite athletes, who have been found to have higher levels of FIH in their muscles than others.

3 Apr 2018

American Gene Technologies receives second immuno-oncology patent

American Gene Technologies International Inc., a leading gene and cell therapy company, today announced receipt of a second immuno-oncology patent on the stimulation of gamma delta T cells for treating solid tumors in epithelial cancers.

20 Mar 2018

New study identifies the body's 'glucostat'

It is the pancreatic islets that have the overall responsibility for maintaining normal blood glucose levels in our bodies, according to a new study by researchers at Karolinska Institutet in Sweden and the University of Miami Miller School of Medicine, USA.

6 Mar 2018