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Researchers discover gene locations affecting wrist bones in children

Pediatric researchers have discovered gene locations affecting bone strength in wrist bones, the most common site for fractures in children. Children who have those genetic variants may be at higher-than-average risk of wrist fractures, and could especially benefit from activities and diets that promote bone strength.

30 Jun 2015

Study reveals molecular basis for endocrine therapy-resistant breast cancer

Mitsuyoshi Nakao, Director of the Institute of Molecular Embryology and Genetics in Kumamoto University and Associate Professor Noriko Saitoh revealed that a cluster of defined, non-coding RNAs are mechanistically involved in endocrine therapy resistance in human breast cancer cells. Furthermore, resveratrol, a kind of polyphenol, was found to repress these RNAs and inhibit the proliferative activity of breast cancer cells which had acquired resistance.

27 May 2015

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease.

8 May 2015

New health-focused code school coming to Chicago

The newest code school in Chicago, CodeAbode, starts classes on June 1. CodeAbode offers "boot camp" and part-time options designed to turn students into web and mobile app developers.

6 May 2015

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

Sangamo BioSciences, Inc. announced that data from clinical, preclinical and research-stage programs focused on the development of ZFP Therapeutics will be presented at the 18th Annual Meeting of the American Society of Gene and Cell Therapy

29 Apr 2015

Study paves way for greater understanding of Attention Deficit Hyperactivity Disorder

Researchers at the Angiocardioneurology Department of the Neuromed Scientific Institute for Research, Hospitalisation and Health Care of Pozzilli (Italy), have found, in animal models, that the absence of a certain enzyme causes a syndrome resembling the Attention Deficit Hyperactivity Disorder (ADHD).

16 Apr 2015

Study: Key signaling pathway in B-cell lymphoma can be blocked using compounds

Cancer researchers from the University of Zurich have identified a key signaling pathway in B-cell lymphoma, a malignant type of blood cancer.

7 Apr 2015

Genomics researchers discover novel gene variants in childhood CVID

Genomics researchers analyzing a rare, serious immunodeficiency disease in children have discovered links to a gene crucial to the body's defense against infections. The finding may represent an inviting target for drugs to treat common variable immunodeficiency (CVID).

27 Feb 2015

New study finds that wandering mind can impart distinct cognitive advantage

Does your mind wander when performing monotonous, repetitive tasks? Of course! But daydreaming involves more than just beating back boredom. In fact, according to a new study published in the Proceedings of the National Academy of Sciences, a wandering mind can impart a distinct cognitive advantage.

24 Feb 2015

Thync electrical neurosignaling reduces brain's response to stress, shows study

Thync today announced results from a study published via bioRxiv that show electrical neurosignaling delivered by its consumer wearable device reduces the brain's response to stress in a chemical-free manner.

13 Feb 2015

Newly found protein in naked mole rat helps ward off cancer

A protein newly found in the naked mole rat may help explain its unique ability to ward off cancer.

5 Feb 2015

CUMC researchers use innovative algorithm to find driving force behind aggressive form of glioblastoma

Using an innovative algorithm that analyzes gene regulatory and signaling networks, Columbia University Medical Center researchers have found that loss of a gene called KLHL9 is the driving force behind the most aggressive form of glioblastoma, the most common form of brain cancer.

10 Oct 2014

Chinese study of serogroup 6 S. pneumoniae finds no antibiotic-resistant clones

A survey of serogroup 6 Streptococcus pneumoniae isolates from children in China has identified no antibiotic-resistant clones, leading the authors to speculate that the isolates may be under antibiotic selective pressure.

8 Sep 2014

Study identifies novel gene that controls nerve conduction velocity linked with MS

A new study published in The American Journal of Pathology identifies a novel gene that controls nerve conduction velocity.

13 Aug 2014

Study identifies three genetic changes linked to increased risk of breast cancer in East Asian women

A new study in East Asian women has identified three genetic changes linked to an increased risk of breast cancer. The research, led by Vanderbilt University investigators, was published online July 20 in Nature Genetics.

24 Jul 2014

More genetic suspects for schizophrenia brought to light

A meta-analysis from the Schizophrenia Working Group of the Psychiatric Genomics Consortium has revealed a large number of previously unreported genetic loci that may have a role in schizophrenia.

23 Jul 2014

Fungus responsible for outbreak of Greek yogurt can threaten health systems

The fungus responsible for an outbreak of contaminated Greek yogurt last year is not harmless after all but a strain with the ability to cause disease, according to research published in mBio-, the online open-access journal of the American Society for Microbiology.

8 Jul 2014

Social environment may influence mood stabiliser adherence

The attitudes of patients with bipolar disorder towards mood-stabilising medications are influenced by their social support system, say researchers.

3 Jul 2014

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child's need for pain-control drugs. The findings suggest that at some point physicians may calibrate pain-medication dosages according to a child's individual genetic makeup.

2 Jul 2014

Researchers explore genetic and cellular mechanisms of retinal development

The circuitry of the central nervous system is immensely complex and, as a result, sometimes confounding. When scientists conduct research to unravel the inner workings at a cellular level, they are sometimes surprised by what they find.

20 Jun 2014