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Study unveils dynamic brain architecture through advanced fMRI techniques Neuroscientists In Spain ...

Researchers from the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, along with a team from the Transylvanian Institute of Neuroscience (Romania), and in collaboration with experts from the Universitat Politècnica de València, have developed an innovative approach to studying brain connections using functional magnetic resonance imaging (fMRI).

11 Sep 2024

New target identified for potential ALS therapy

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects motor neurons.

10 Sep 2024

A fluorescent probe for studying serotonin in depression models

Serotonin in depression is highly relevant in diagnosis, treatment, and drug development. To better study this area, a Chinese team has now developed a fluorescent probe for imaging processes that is highly sensitive and selective toward serotonin.

6 Sep 2024

Hybrid neuron-glia cells found in glioma may impact tumor growth

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital have uncovered a new cell type in the human brain.

5 Sep 2024

New insights into stiff-person syndrome, advancing diagnosis and treatment

Research explores the complexities of diagnosing and treating stiff-person syndrome, emphasizing the uncertain role of GAD antibodies and the promise of novel therapies.

5 Sep 2024

CDK4/6 inhibitors show promise for pediatric high-grade glioma treatment

CDK4/6 inhibitors, which are already FDA approved for the treatment of other forms of cancer, show early signs of promise in the treatment of a subtype of pediatric high-grade glioma, according to new research from Dana-Farber Cancer Institute and the Institute of Cancer Research in London.

3 Sep 2024

Neural circuits provide clues for better AI matching solutions

When you ask a rideshare app to find you a car, the company's computers get to work. They know you want to reach your destination quickly.

2 Sep 2024

Study reveals neural processes behind morphine's pain relief

In a study published in Science, researchers at Karolinska Institutet describe the neural processes behind how morphine relieves pain. This is valuable knowledge because the drug has such serious side effects.

29 Aug 2024

New photoacoustic probes could revolutionize brain activity imaging

To understand the brain better, we need new methods to observe its activity.

28 Aug 2024

New implant offers hope for nerve repair after spinal cord injury

A research team at RCSI University of Medicine and Health Sciences has developed a new implant that conveys electrical signals and may have the potential to encourage nerve cell (neuron) repair after spinal cord injury.

28 Aug 2024

Scientists discover how a gut insulin antagonist controls fat loss in C. elegans by modulating brain signals

Researchers have identified an endogenous insulin antagonist, INS-7, in Caenorhabditis elegans that modulates fat loss by inhibiting a gut-to-brain signaling pathway involving the neuropeptide FLP-7.

27 Aug 2024

GPePV neurons identified as key players in controlling cocaine addiction behaviors

Researchers examine how GPePV cells regulate cocaine-induced behaviors through interactions with ventral tegmental area dopamine cells.

25 Aug 2024

Study shows frequent mitochondrial DNA insertion in the brain cells

As direct descendants of ancient bacteria, mitochondria have always been a little alien.

22 Aug 2024

The critical role of PGK1 in Parkinson's disease

An enzyme called PGK1 has an unexpectedly critical role in the production of chemical energy in brain cells, according to a preclinical study led by researchers at Weill Cornell Medicine. The investigators found that boosting its activity may help the brain resist the energy deficits that can lead to Parkinson's disease.

21 Aug 2024

ASTN2 gene knockout in mice reveals key autism-related behaviors

More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with language, social communication, hyperactivity, and repetitive movements.

16 Aug 2024

Study: Early brain wiring driven by spontaneous cellular activity

In humans, the process of learning is driven by different groups of cells in the brain firing together. For instance, when the neurons associated with the process of recognizing a dog begin to fire in a coordinated manner in response to the cells that encode the features of a dog - four legs, fur, a tail, etc. - a young child will eventually be able to identify dogs going forward.

16 Aug 2024

New insights into lipid-induced senescence in dopaminergic neurons

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, "Lipid accumulation drives cellular senescence in dopaminergic neurons."

13 Aug 2024

MUSC researchers uncover the surprising role of the dorsal peduncular nucleus in opioid addiction

Opioids, like the commonly prescribed pain reliever oxycodone, are known for being highly addictive. In 2022, nearly 85,000 people died from an opioid overdose in the U.S. according to the Centers for Disease control.

12 Aug 2024

Researchers uncover mechanism for storing and using visual knowledge in the brain

Our brain interprets visual information by combining what we see with what we already know. A study published in the journal Neuron by researchers at the Champalimaud Foundation, and supported by the CaixaResearch Health Call of the la Caixa Foundation, reveals a mechanism for learning and storing this existing knowledge about the world.

12 Aug 2024

Study sheds light on neuronal synchronization and conscious experience

For decades, scientists have focused on how the brain processes information in a hierarchical manner, with different brain areas specialized for different tasks.

12 Aug 2024