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Specialized lung cells appear in the developing fetus much earlier than previously thought

Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.

19 Feb 2019

Fetal signaling pathways may offer future opportunities to treat lung damage

Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study published this week in the Proceedings of the National Academy of Sciences reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.

18 Feb 2019

Breakthrough study highlights the promise of cell therapies for muscular dystrophy

The University of Minnesota Medical School continues its legacy of advancing cell replacement therapies with a scientific breakthrough that highlights the promise of cell therapies for muscular dystrophy.

14 Feb 2019

Study discovers new therapy for aggressive blood cancer

Acute myeloid leukemia is the most common form of acute leukemia. It is characterized by an increase of malignant myeloid progenitor cells at the expense of mature blood cells.

13 Feb 2019

New study provides insights into developmental organization of the brain

What makes us human, and where does this mysterious property of "humanness" come from? Humans are genetically similar to chimpanzees and bonobos, yet there exist obvious behavioral and cognitive differences.

13 Feb 2019

New model sheds light on how small cell lung cancer is initiated

Scientists from Weill Cornell Medicine have developed a stem-cell-based model of small cell lung cancer that will help them understand how the disease is initiated and how it progresses.

11 Feb 2019

Study explains effects of aging on endothelial health and vascular regenerative capacity

The endothelium plays an important role in cardiovascular regulation, from blood flow to platelet aggregation, immune cell infiltration and demargination.

28 Dec 2018

Glial cell maturation is severely impaired in patients with Huntington's disease

The neurological disorder Huntington's disease causes behavioral and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the brain's support cells, researchers from the University of Copenhagen demonstrate in a new study based on mice trials.

24 Dec 2018

Study reveals mechanism behind failed remyelination in MS

Researchers have discovered that in adult stem cells, the activation of a specific transcription factor induces pathological quiescence and that this is deactivated in MS.

18 Dec 2018

New research lays out potential path for treatment of Huntington’s disease

New research gives scientists a clearer picture of what is happening in the brains of people with Huntington's disease and lays out a potential path for treatment.

14 Dec 2018

Scientists support original theory about pancreas regeneration

A contentious debate among diabetes researchers has surrounded the regeneration of pancreatic insulin-producing cells: not if these cells regenerate, but rather how.

5 Dec 2018

Advances in gene therapy for inherited blood disorders

Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us.

4 Dec 2018

Using nanocarrier-delivered microRNA to target sepsis

One in three patients who die in the U.S. dies of sepsis, according to the Centers for Disease Control and Prevention. It is one of the leading causes of death in intensive care units and, with an estimated price tag of $20 billion in 2011, the most expensive condition that hospitals treat.

3 Dec 2018

Study points toward new strategies for managing organ transplantation

The human intestine may provide up to 10 percent of blood cells in circulation from its own reservoir of blood-forming stem cells, a surprising new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

30 Nov 2018

New strategy for developing cell replacement therapies to combat type 1 diabetes

Scientists have discovered the signals that determine the fate of immature cells in the pancreas. The research shows that they are very mobile and that their destiny is strongly influenced by their immediate environment.

29 Nov 2018

DNA mutations in healthy and leukemic blood stem cells do not differ, shows research

Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ.

29 Nov 2018

Study provides new way to treat multiple sclerosis

Nerve cells stripped of their insulation can no longer carry vital information, leading to the numbness, weakness and vision problems often associated with multiple sclerosis. A new study shows an overlooked source may be able to replace that lost insulation and provide a new way to treat diseases like MS.

27 Nov 2018