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In-depth assessment of muscle biopsies in patients with long COVID

Researchers analyzed skeletal muscle biopsies of patients with persistent fatigue and malaise post-exertion to determine the underlying mechanisms of long COVID.

20 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

How effective has the bivalent booster COVID vaccination been?

In a recent study published in the journal Eurosurveillance, researchers estimated the effectiveness of bivalent messenger ribonucleic acid (mRNA) vaccines targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 subvariant and the original Wuhan-Hu1 strain against Omicron infections in the vaccinated population of the Netherlands between 26 September and 19 December 2022.

19 Feb 2023

Gut dysbiosis and sepsis susceptibility among pregnant women

Researchers describe the role of gut dysbiosis during pregnancy in promoting excessive macrophage pyroptosis, which increases vulnerability to sepsis.

19 Feb 2023

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Researchers used a non-human primate model to show that Sotrovimab, a commercial mAb also known as Xevudy, was fully effective against SARS-CoV-2 Omicron BA.5 sub-lineage and its derivatives, such as BQ.1.1.

17 Feb 2023

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Researchers performed a retrospective population-wide cohort study using anonymized data in Hong Kong, China, between February 26 and July 3, 2022.

16 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

In a recent study posted to the bioRxiv* preprint server, researchers identified a novel antiviral pathway different from the interferon (IFN) pathway that inhibited poxvirus(es) replication.

15 Feb 2023

Meta-analysis showcases the long-term benefits of COVID-19 vaccines against hospitalization & death

A meta-analysis on the long-term vaccine effectiveness of four COVID-19 vaccines.

14 Feb 2023

New insights into the role of T-cells during long COVID

Researchers characterize the trajectory of long COVID in patients eight months after recovering from infection.

14 Feb 2023

Do nuts help with type 2 diabetes?

Type 2 diabetes is a metabolic disorder that affects one in ten people worldwide. There has been an alarming increase of 16% in the global prevalence of type 2 diabetes over the past two years.

13 Feb 2023

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

SARS-CoV-2 does not suppress the replication of influenza A in simultaneous or sequential co-infections.

13 Feb 2023

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination

Researchers examined the factors associated with stroke following coronavirus disease 2019 (COVID-19) vaccination.

13 Feb 2023

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Researchers developed spherical hydrogel inhalation for enhanced lung defense to protect against SARS-CoV-2 infections.

13 Feb 2023

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Researchers evaluated the immunogenicity of two vaccine candidates, Pfs25 and PfCSP, based on the mRNA-lipid nanoparticle (LNP) platform.

13 Feb 2023

Fear and anxiety during the COVID-19 pandemic associated with new alcohol use disorder diagnoses

Researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and new diagnoses of alcohol use disorder (AUD) in the two years since the onset of the coronavirus disease 2019 (COVID-19) pandemic.

13 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Longitudinal assessment of gastrointestinal virome of mothers and infants

In a recent study published in Cell Host & Microbe, researchers comparatively assessed the gastrointestinal virome of mothers and infants.

10 Feb 2023

Ribonucleic Acid News and Research

In-depth assessment of muscle biopsies in patients with long COVID

Genome editing prevents hypertrophic cardiomyopathy in mice

How effective has the bivalent booster COVID vaccination been?

Gut dysbiosis and sepsis susceptibility among pregnant women

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Delayed presentation of MIS-C following COVID-19

Comparative study on retinoic acid-inducible gene-I of humans and bats

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

Meta-analysis showcases the long-term benefits of COVID-19 vaccines against hospitalization & death

New insights into the role of T-cells during long COVID

Do nuts help with type 2 diabetes?

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Fear and anxiety during the COVID-19 pandemic associated with new alcohol use disorder diagnoses

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Longitudinal assessment of gastrointestinal virome of mothers and infants

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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