Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

New discovery may help researchers tackle mitochondrial diseases and age-related diseases

Buck Institute faculty Judith Campisi, PhD, says age researchers need to stop thinking of cellular senescence, now accepted as an important driver of aging, as a single phenotype that stems from genotoxic stress. Research from her lab reveals that cellular senescence, a process whereby cells permanently lose the ability to divide, is also induced by signaling from dysfunctional mitochondria - and that the arrested cells secrete a distinctly different "stew" of biologically active factors in a process unrelated to the damaging free radicals that are created in mitochondria as part of oxygen metabolism.

13 Jan 2016

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

In humans the differentiation of stem cells into hundreds of specialized cell types is vital. Differentiation drives development from fertilized egg to a newborn, and it underlies the continuous replacement of the 5 billion cells that die every hour in an adult. On the downside, mutations in differentiation pathways of different cell types can be drivers of cancers.

13 Jan 2016

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Researchers have identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia – a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer.

12 Jan 2016

TRL becomes primary distributor of Kirkstall's QuasiVivo system in the US and Canada

Triangle Research Labs, LLC and Kirkstall, Ltd, are pleased to announce TRL as the primary distributor of Kirkstall's 3-D cell fluidic culture system, QuasiVivo, in the US and Canada.

12 Jan 2016

Scientists discover protein interaction that describes aggressive subtype of medulloblastoma

Scientists at St. Jude Children's Research Hospital and the University of Würzburg in Germany have identified a protein interaction that is a hallmark of an aggressive subtype of medulloblastoma and that may provide a new treatment strategy.

12 Jan 2016

McMaster University researchers take a giant leap in detecting early stages of leukemia

McMaster University researchers have taken a giant leap in identifying the early stages of a deadly cancer and predicting how it will develop in individuals.

11 Jan 2016

Clontech Laboratories launches Guide-it CRISPR/Cas9 Gesicle Production System

Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara Bio Inc., today announced the launch of the Guide-it CRISPR/Cas9 Gesicle Production System. This system provides an innovative method to deliver Cas9/single guide RNA (sgRNA) ribonucleoprotein complexes to a broad range of cell types.

11 Jan 2016

Using skin cells to treat injured hearts

Following a heart attack or other heart trauma, the heart is unable to replace its dead cells. Patients are often left with little option other than heart transplants, which are rarely available, or more recently cell therapies that transplant heart cells into the patient's heart. In far too many cases, however, the transplanted heart cells do not engraft well, resulting in poor recovery.

11 Jan 2016

Research could lead to new treatment for Rett Syndrome, other forms of autism

Penn State scientists have discovered a novel drug target and have rescued functional deficits in human nerve cells derived from patients with Rett Syndrome, a severe form of autism-spectrum disorder.

11 Jan 2016

DNA-binding protein acts like genetic traffic signal to orchestrate early stage embryonic development

New research by UC San Francisco stem cell biologists has revealed that a DNA-binding protein called Foxd3 acts like a genetic traffic signal, holding that ball of undifferentiated cells in a state of readiness for its great transformation in the third week of development.

11 Jan 2016

U-M research could lead to new ways of fighting X-linked diseases in girls and women

Nearly every girl and woman on Earth carries two X chromosomes in nearly every one of her cells -- but one of them does (mostly) nothing. That's because it's been silenced, keeping most of its DNA locked up and unread like a book in a cage.

11 Jan 2016

Anthony Nolan introduces new tissue typing method that could revolutionise stem cell transplantation

Anthony Nolan has today launched a new tissue typing method that could significantly improve stem cell transplant outcomes.

8 Jan 2016

New class of sound wave could lead to revolution in stem cell therapy

Acoustics experts have created a new class of sound wave - the first in more than half a century - in a breakthrough they hope could lead to a revolution in stem cell therapy.

7 Jan 2016

Promising novel approach to treat gynecologic tumors

UCLA scientists have developed a promising novel method to treat gynecologic tumors. The approach focuses on a protein called p53, which is commonly mutated in women who have high-grade serous ovarian cancer, the deadliest form of reproductive cancer. In many women with the disease, the cancer is very advanced by the time it is diagnosed and is therefore difficult to treat.

7 Jan 2016

New CRISPR technology can be used to make designer babies

How should we handle the new CRISPR technology that can both advance science and medicine, but also be used to make designer babies? Scientist and author Paul Knoepfler tackles this and other difficult questions related to this revolutionary technology in his new book, GMO Sapiens: The Life-Changing Science of Designer Babies, targeted at a broad, lay audience.

7 Jan 2016

Eliminating the 'bad seeds' of liver cancer

Researchers have found the 'bad seeds' of liver cancer and believe they could one day reprogram them to remain responsive to cancer treatment, a new study has found.

7 Jan 2016

Combining NELL-1 with BMP2 therapy may promote bone development

Bone morphogenetic protein-2 (BMP2) is used clinically to promote bone repair. However, the high BMP2 concentrations required to stimulate bone growth in humans may produce life-threatening adverse effects such as cervical swelling in spinal fusion procedures, a problem that prompted an FDA warning in 2008.

7 Jan 2016

Scientists successfully create fully-functional pancreatic cells from human skin cells

Scientists at the Gladstone Institutes and the University of California, San Francisco have successfully converted human skin cells into fully-functional pancreatic cells. The new cells produced insulin in response to changes in glucose levels, and, when transplanted into mice, the cells protected the animals from developing diabetes in a mouse model of the disease.

6 Jan 2016

UNC researchers uncover new potential strategy to kill cancerous cells in the brain

Rapidly dividing cells rely on an enzyme called Dicer to help them repair the DNA damage that occurs as they make mistakes in copying their genetic material over and over for new cells. UNC Lineberger Comprehensive Cancer Center researchers have built on the discovery of Dicer's role in fixing DNA damage to uncover a new potential strategy to kill rapidly dividing, cancerous cells in the brain.

6 Jan 2016

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

My laboratory’s long standing interest is the study of the signaling capabilities of stem cells, both under homeostatic conditions

From Beckman Coulter Life Sciences - Flow Cytometry 5 Jan 2016

Stem Cells News and Research

Further Reading

New discovery may help researchers tackle mitochondrial diseases and age-related diseases

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

TRL becomes primary distributor of Kirkstall's QuasiVivo system in the US and Canada

Scientists discover protein interaction that describes aggressive subtype of medulloblastoma

McMaster University researchers take a giant leap in detecting early stages of leukemia

Clontech Laboratories launches Guide-it CRISPR/Cas9 Gesicle Production System

Using skin cells to treat injured hearts

Research could lead to new treatment for Rett Syndrome, other forms of autism

DNA-binding protein acts like genetic traffic signal to orchestrate early stage embryonic development

U-M research could lead to new ways of fighting X-linked diseases in girls and women

Anthony Nolan introduces new tissue typing method that could revolutionise stem cell transplantation

New class of sound wave could lead to revolution in stem cell therapy

Promising novel approach to treat gynecologic tumors

New CRISPR technology can be used to make designer babies

Eliminating the 'bad seeds' of liver cancer

Combining NELL-1 with BMP2 therapy may promote bone development

Scientists successfully create fully-functional pancreatic cells from human skin cells

UNC researchers uncover new potential strategy to kill cancerous cells in the brain

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

eBook: Integrated solutions for mesenchymal stem cell research and culture eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo