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Left ventricular assistant devices extend lives of patients too sick for transplant

Pumps implanted into the chest to maintain circulation can significantly extend the lives of the sickest patients in end-stage heart failure who are not candidates for heart transplantation, according to the results of a clinical trial led by Duke University Medical Center cardiologists.

28 Nov 2005

Analysis of Fcg Receptor haplotypes in rheumatoid arthritis

People with a specific combination of variants of two genes, encoding two different receptors for the antibody Fc gamma, are three times more likely to develop rheumatoid arthritis than individuals with different variant combinations.

28 Nov 2005

Megestrol acetate may combat weight loss during radiation treatments

A new study by researchers at Wake Forest University Baptist Medical Center and colleagues shows that a drug originally used to treat breast cancer may help combat the severe weight loss that can plague patients undergoing radiation treatment for lung and head and neck cancer.

28 Nov 2005

Loss of genes on chromosome 1 or 11 raises the risk of death from the children's cancer neuroblastoma

A new study reports that a loss of genes on chromosome 1 or chromosome 11 raises the risk of death from the children's cancer neuroblastoma, even when other indicators seem to point to a lower-risk form of the disease.

28 Nov 2005

Distance to radiation facilities has an inverse relationship with breast-conserving surgery with radiation use

The farther away a woman lives from a radiation therapy facility, the less likely she is to get lumpectomy with adjuvant radiation therapy for early stage breast cancer, and may instead get mastectomy, according to a new study.

28 Nov 2005

Zinc supplements safe for chidren with HIV

Zinc-deficient children living in communities where they do not receive adequate amounts of zinc from their diet should be given supplements, even if they are HIV-infected, according to researchers from the Johns Hopkins Bloomberg School of Public Health and other institutions.

26 Nov 2005

Cellular clues to vitamin A resistance in lung cancer

Vitamin A deficiency has been associated with the development of lung cancer in laboratory studies. However, clinical trials of natural and synthetic derivatives of vitamin A, called retinoids, for the prevention of lung cancer have been largely unsuccessful in the general population.

26 Nov 2005

Two novel drugs kill breast cancer tumor cells

Two new drugs, when combined, killed up to 75 percent of breast cancer tumor cells in mice and suppressed the regrowth of tumors, according to researchers at the Virginia Commonwealth University Massey Cancer Center.

26 Nov 2005

New and promising antibody profiling technique to test for non-small cell lung cancer cases

Biomedical scientists have revealed a new and promising antibody profiling technique that provides a high degree of early diagnostic accuracy for non-small cell lung cancer cases.

26 Nov 2005

48% of people with diabetes are not using aspirin to reduce risk of heart attack and stroke

Survey results released by the American College of Preventive Medicine (ACPM) found that nearly half (48%) of U.S. adults 40+ with diabetes are not utilizing aspirin therapy to reduce their risk of recurrent heart attack or stroke nor had they reported discussing such therapy with their healthcare provider.

26 Nov 2005

United Kingdom has among the highest reported rates of primary resistance to HIV drugs worldwide

Those infected with HIV in the UK have one of the highest rates of resistance to anti-HIV drugs of anywhere in the world, prompting fears of a second wave epidemic of resistant virus, a new study claims in the British Medical Journal (BMJ).

26 Nov 2005

High blood pressure research advances efforts to tailor drugs to individual patients

Having high blood pressure and a particular genetic alteration dramatically increases the risk of heart attack, stroke or death, and may explain why some hypertensive patients fare worse than others - even if they take the same medication, University of Florida researchers announced.

26 Nov 2005

Fear gene discovered

In the Nov. 18 issue of Cell, researchers report the discovery of a gene that controls the ability to react with appropriate fear to impending danger.

26 Nov 2005

"Get With The Guidelines" programs improve care

After one year - Get With The GuidelinesSM programs used in hospitals significantly improved care for almost 30,000 coronary artery disease patients of all ages and sexes, according to research reported at the American Heart Association's Scientific Sessions 2005.

26 Nov 2005

$Radiotherapy for certain cancers increases the risk of pelvic fractures$

Radiotherapy for certain cancers increases the risk of pelvic fractures

A new study suggests that older women who receive pelvic radiation treatment for cervical, anal or rectal cancer may have an increased risk of pelvic fracture.

24 Nov 2005

New drug CellCept far more effective in treating kidney problems in lupus patients

A new study has shown that the drug CellCept is just as good at fighting kidney complications from the debilitating disease lupus with far fewer side effects than standard treatment using the cancer drug Cytoxan.

24 Nov 2005

Compound from Salinispora (marine bacteria) kills blood cancer cells

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

21 Nov 2005

Significant association between gingivitis and preterm birth

Pregnant women will want to include a periodontal evaluation as part of their prenatal care. That's because researchers found that periodontal treatment significantly reduced the risk of having a preterm birth or a low birthweight infant, according to a study published in the Journal of Periodontology.

21 Nov 2005

Re-opening of carotid arteries in stroke has high success rate with stenting

University of Pittsburgh researchers report a high level of effectiveness in re-opening completely blocked internal carotid arteries (ICA) as late as two to three days after acute stroke symptoms by using stents.

21 Nov 2005

Tamoxifen reduces the risk of invasive and noninvasive breast cancer

Data from additional years of follow-up of a large randomized placebo-controlled clinical trial of tamoxifen for the prevention of breast cancer confirm that the drug reduces the risk of invasive and noninvasive breast cancer, according to a report that appears in the current issue of the Journal of the National Cancer Institute.

21 Nov 2005

Therapy News and Research

Left ventricular assistant devices extend lives of patients too sick for transplant

Analysis of Fcg Receptor haplotypes in rheumatoid arthritis

Megestrol acetate may combat weight loss during radiation treatments

Loss of genes on chromosome 1 or 11 raises the risk of death from the children's cancer neuroblastoma

Distance to radiation facilities has an inverse relationship with breast-conserving surgery with radiation use

Zinc supplements safe for chidren with HIV

Cellular clues to vitamin A resistance in lung cancer

Two novel drugs kill breast cancer tumor cells

New and promising antibody profiling technique to test for non-small cell lung cancer cases

48% of people with diabetes are not using aspirin to reduce risk of heart attack and stroke

United Kingdom has among the highest reported rates of primary resistance to HIV drugs worldwide

High blood pressure research advances efforts to tailor drugs to individual patients

Fear gene discovered

"Get With The Guidelines" programs improve care

Radiotherapy for certain cancers increases the risk of pelvic fractures

New drug CellCept far more effective in treating kidney problems in lupus patients

Compound from Salinispora (marine bacteria) kills blood cancer cells

Significant association between gingivitis and preterm birth

Re-opening of carotid arteries in stroke has high success rate with stenting

Tamoxifen reduces the risk of invasive and noninvasive breast cancer

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