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Molecular origins of diabetes

An unexpected twist to a discovery reported just two months ago may significantly improve our understanding about the molecular origins of diabetes.

14 Nov 2005

People taking highly active antiretroviral therapy for HIV infection remain susceptible to tuberculosis

...though the risk is lower than for HIV-infected patients not on HAART, according to an article in the Dec. 15 issue of Clinical Infectious Diseases, now available online.

13 Nov 2005

Researchers can now identify patients likely to respond to cancer drug therapy

Researchers at UCLA's Jonsson Cancer have identified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent.

13 Nov 2005

University of Alberta researchers pioneer gene therapy to restore alveoli and lung capillaries in damaged rat lungs

The good news is that medical advances in perinatal care have allowed us to save many more premature babies. The bad news is they're often at risk of developing bronchopulmonary dysplasia--a chronic lung disease caused by having to place the tiny infants on ventilators and oxygen-rich therapy for acute respiratory failure.

13 Nov 2005

Pretreating a vein graft with edifoligide prior to coronary bypass graft surgery does not lower the rate of graft failure

Coronary artery bypass graft (CABG) surgery is one of the most common surgical procedures performed in the United States, according to background information in the article. In appropriately selected patients, CABG surgery results in improved survival, relief of angina, and improved quality of life. Despite frequent use of artery grafts, vein grafts remain the most frequently used conduit.

13 Nov 2005

Zyflamend shows promise in the early treatment of prostate cancer

Data from the Columbia University Department of Urology demonstrates that Zyflamend, a unique herbal extract preparation, suppresses the growth of prostate cancer cells and induces prostate cancer cells to self-destruct via a process called "apoptosis."

13 Nov 2005

Cancer survivors require tailored follow-up plans

Citing shortfalls in the care currently provided to the country's 10 million cancer survivors, a new report recommends that each cancer patient receive a "survivorship care plan."

13 Nov 2005

Use of traction to help treat low back pain has no benefit

"Traction was introduced before it was properly evaluated in high-quality randomized trials, and as an intervention is already part of usual practice,” said lead author Judy M.A. Clarke, M.D. “It is hard to convince health care providers not to use it."

10 Nov 2005

Fc gamma receptor gene variants associated with rheumatoid arthritis

People with a specific combination of variants of two genes, encoding two different receptors for the antibody Fc gamma, are three times more likely to develop rheumatoid arthritis than individuals with different variant combinations.

10 Nov 2005

Aspirin and ibuprofen may significantly reduce the risk of esophageal cancer among people with Barrett's esophagus

Aspirin and other nonsteroidal anti- inflammatory drugs, such as ibuprofen, may significantly reduce the risk of esophageal cancer among people with Barrett's esophagus, a precancerous condition associated with chronic heartburn that affects an estimated 1 million to 2 million Americans.

8 Nov 2005

Introgen's INGN 241 combined with Celebrex kills breast cancer cells

Introgen Therapeutics, Inc. today reported the publication of preclinical data demonstrating that INGN 241 works synergistically with celecoxib (Celebrex) marketed by Pfizer to inhibit the growth and increase apoptosis (cell death) of breast cancer cells.

8 Nov 2005

Young scientists turn to gel to ease side-effects of cancer treatment

Three young scientists in the University of York’s Department of Chemistry have developed a gel that could spare cancer patients some of the unpleasant and dangerous side-effects of radiotherapy.

8 Nov 2005

Sildenafil reverses symptoms of Raynaud's

German researchers have discovered yet another use for Viagra (sildenafil), they say it relieves the symptoms and improves the circulation of patients with Raynaud's phenomenon.

8 Nov 2005

Xolair (omalizumab) brings new hope for severe asthma sufferers

The launch of a new drug to treat asthma has given new hope to people with severe asthma.

8 Nov 2005

Those most at risk of Alzheimer's would allow loved ones enroll them in research

According to a new survey most people at high risk of Alzheimer's disease would be willing to have their loved ones enroll them in research studies when they could no longer give consent themselves.

8 Nov 2005

Chlamydia pneumoniae may cause vision problems

Researchers at the Massachusetts Eye and Ear Infirmary (MEEI) have found that Chlamydia pneumoniae, a bacterium linked to heart disease and capable of causing chronic inflammation, was present in the diseased eye tissue of five out of nine people with neovascular, or "wet," age-related macular degeneration (AMD).

7 Nov 2005

Cell fusion triggered by viruses is a possible contributing factor in the development of human cancer

In some cases, the fusion of human cells is a normal process that leads, for instance, to the formation of muscle and bone. Viral infections can also cause cell fusion, but cells fused by viruses are widely considered to be harmless because they are generally believed to die without consequences for the host.

7 Nov 2005