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Recent releases in Global Health

According to a Lancet Comment, "alcohol remains conspicuously absent from the larger field of research and programming in HIV and substance use. ... Patterns of hazardous alcohol consumption prevail in countries with the most severe HIV epidemics, notably eastern and southern Africa." In addition, "hazardous drinking patterns also dominate in the concentrated epidemics of eastern Europe and Asia, where alcohol use by injecting drug users and other marginalised groups might be an additional barrier to effective efforts to prevent HIV infection."

7 Aug 2010

Merck's two pivotal boceprevir Phase III registration studies for chronic HCV meet primary endpoint

Merck reported that two pivotal Phase III registration studies for boceprevir, its investigational oral hepatitis C protease inhibitor, have been completed and met the primary endpoints: in both studies in patients with chronic hepatitis C virus (HCV) genotype 1 infection, the addition of boceprevir to treatment with PEGINTRON® and REBETOL® significantly increased the number of patients who achieved sustained virologic response, compared to control groups that received Peg/riba plus placebo.

5 Aug 2010

Phase I/II clinical study data of OncoVEXGM-CSF for head and neck cancer published in Clinical Cancer Research

BioVex Inc, a company developing new generation biologics for the treatment of cancer and prevention of infectious disease, announces that the data from its completed Phase I/II clinical study of OncoVEXGM-CSF for the first line treatment of head and neck cancer is being published today in Clinical Cancer Research, an ASCO publication.

2 Aug 2010

Adequate recovery sleep duration important for coping with effects of chronic sleep restriction on the brain

A study in the Aug. 1 issue of the journal Sleep suggests that a dose of extra sleep on the weekend may be good medicine for adults who repeatedly stay up too late or wake up too early during the workweek. However, even a night of 10 hours in bed may not be enough to cure the negative effects of chronic sleep restriction.

2 Aug 2010

Intrinsic brain connectivity in fibromyalgia associated with chronic pain intensity

A recent study from researchers at Massachusetts General Hospital and University of Michigan provides the first direct evidence of linkage between elevated intrinsic (resting-state) brain connectivity and spontaneous pain intensity in patients with fibromyalgia (FM). This research shows an interaction of multiple brain networks, offering greater understanding of how pain arises. Details of the study appear online and in the August issue of Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

30 Jul 2010

Anthera initiates PEARL-SC Phase 2b study of A-623 for lupus

Anthera Pharmaceuticals, Inc., a biopharmaceutical company developing drugs to treat serious diseases associated with inflammation, today announced it has initiated PEARL-SC, the Phase 2b study of A-623, a novel inhibitor of B-Cell Activating Factor, or BAFF, for the treatment of Systemic Lupus Erythematosus (lupus). Lupus patients suffer from a chronic autoimmune disease, which often leads to severe skin rash, fatigue, joint pain, major organ complications, and cardiovascular disease.

30 Jul 2010

Resting brain activity associated with spontaneous fibromyalgia pain

29 Jul 2010

AVEO second-quarter total revenues increase to $15.6 million

AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics, today provided an update on recent research and development (R&D) and business accomplishments, and announced financial results for the quarter ended June 30, 2010.

29 Jul 2010

Allos reports topline results from Phase 2b trial of FOLOTYN vs erlotinib in advanced NSCLC

Allos Therapeutics, Inc. today announced topline results from the Company's randomized Phase 2b investigational trial of FOLOTYN® (pralatrexate injection) versus erlotinib in patients with Stage IIIB/IV (advanced) non-small cell lung cancer (NSCLC) who had received one or two prior systemic treatments including at least one prior platinum-based regimen. The objective of the trial was to estimate the efficacy of FOLOTYN compared to that of erlotinib as assessed by overall survival.

28 Jul 2010

Survey provides insight on roles, responsibilities for improved, sustainable workplace health

Employers should be active partners in the overall health of their employees and can play a strong role by encouraging them to take responsibility for their own health. While the thirteenth edition of The sanofi-aventis Healthcare Survey suggests that no employer or employee would dispute the return-on-investment from benefit plans such as prescription drugs, dental care, or employee assistance programs, improved and sustainable health in the workplace can only be achieved by a deeper commitment to early disease detection, preventative care, and wellness in general.

28 Jul 2010

Regeneron second-quarter total revenues increase to $115.9 million

Regeneron Pharmaceuticals, Inc. announced financial and operating results for the second quarter of 2010. The Company reported a net loss of $25.5 million, or $0.31 per share (basic and diluted), for the second quarter of 2010 compared with a net loss of $14.9 million, or $0.19 per share (basic and diluted), for the second quarter of 2009.

28 Jul 2010

CIHR grants $2.5 million to probe impact of physical activity on breast cancer

Over the next five years, a diverse, multi-disciplinary team of researchers led by Dr. Kerry Courneya of the University of Alberta and Dr. Christine Friedenreich of Alberta Health Services will conduct a series of five large research projects to probe the impacts of physical activity on breast cancer thanks to a $2.5 million team grant over five years from the Canadian Institutes of Health Research (CIHR).

28 Jul 2010

Need for better understanding of appropriate treatment choices for children with insomnia: Study

A new survey of child psychiatrists indicates that insomnia is a major problem among children in mental health treatment and at least a quarter of these patients are given sleep medication. The results of the survey, conducted by Judith Owens, MD, a sleep expert with Hasbro Children's Hospital, and colleagues, suggests that management of insomnia in this population is a common practice, although the clinical approach varies widely. The study is published in the August 2010 edition of Sleep Medicine.

27 Jul 2010

Council seeks to limit medical resident working hours for improved patient care

As the Accreditation Council for Graduate Medical Education seeks to improve patient care by further limiting the hours worked by medical residents, the Journal of Surgical Research will published a new study online on Monday reporting that outcomes in two common surgeries - appendectomy and laparoscopic cholecystectomy - were similar among residents who had worked less than 16 hours and those who had worked more than 16 hours.

26 Jul 2010

VA approves $2.8M for Gulf War Veterans' illness research program

The Department of Veterans Affairs (VA) has approved $2.8 million to fund three new research projects that focus on testing or developing new treatments for illnesses affecting Veterans who served in the Gulf War 1990-1991. The research incorporates recommendations of the department's Gulf War Veterans' Illnesses Task Force.

22 Jul 2010

Current myths vs. realities in global AIDS funding

Activists at the International AIDS Conference in Vienna are charging developed and developing country governments with writing checques that bounce to the millions of people in need of lifesaving HIV treatment. Despite the gains in treatment numbers reported by WHO, the International Treatment Preparedness Coalition's (ITPC), latest report, Rationing Funds, Risking Lives, documents early warnings of the global pullback on AIDS commitment and funding.

22 Jul 2010

ATLIS 2010 shows gap in patient-physician dialogue that may negatively impact patients' quality of life

Results from the landmark AIDS Treatment for Life International Survey, a multi-country survey of more than 2,000 people living with HIV/AIDS, revealed a significant gap in patient-physician dialogue about critical health-related conditions that may negatively impact patients' overall long-term health, quality of life, and treatment outcomes.

21 Jul 2010

Endovenous laser treatment can painlessly remove varicose, spider veins

Up until approximately a decade ago, vein stripping was the only means of eradicating unsightly varicose veins. This method involved making an incision in the leg, and using a hooked wire to pull the affected vein out of the body. The invasiveness of vein stripping often resulted in an overnight hospital stay and considerable restriction of physical activity for up to a month. However, since the laser surgery method first became FDA approved ten years ago, it has come a long way in allowing for more convenient, painless and rapid removal of problematic veins. One particular organization, the Renaissance Laser and Vein Institute, has become a beacon of successful laser treatment for phlebitis sufferers in Los Angeles and Southern California.

21 Jul 2010

Preventative measures to avoid Lyme disease

Research on the population of black-legged ticks, which can transmit Lyme disease from host animals to humans, reinforces that it is important to take preventative measures when spending time outdoors.

21 Jul 2010

Phase 3 study: Tapentadol ER lowers incidence of gastrointestinal adverse events

A Phase 3 open-label study, recently published online by Pain Practice, has compared tapentadol extended release tablets, an investigational pain medication, to an existing prescription pain medication, oxycodone controlled release tablets.

20 Jul 2010

Fatigue News and Research

Recent releases in Global Health

Merck's two pivotal boceprevir Phase III registration studies for chronic HCV meet primary endpoint

Phase I/II clinical study data of OncoVEXGM-CSF for head and neck cancer published in Clinical Cancer Research

Adequate recovery sleep duration important for coping with effects of chronic sleep restriction on the brain

Intrinsic brain connectivity in fibromyalgia associated with chronic pain intensity

Anthera initiates PEARL-SC Phase 2b study of A-623 for lupus

Resting brain activity associated with spontaneous fibromyalgia pain

AVEO second-quarter total revenues increase to $15.6 million

Allos reports topline results from Phase 2b trial of FOLOTYN vs erlotinib in advanced NSCLC

Survey provides insight on roles, responsibilities for improved, sustainable workplace health

Regeneron second-quarter total revenues increase to $115.9 million

CIHR grants $2.5 million to probe impact of physical activity on breast cancer

Need for better understanding of appropriate treatment choices for children with insomnia: Study

Council seeks to limit medical resident working hours for improved patient care

VA approves $2.8M for Gulf War Veterans' illness research program

Current myths vs. realities in global AIDS funding

ATLIS 2010 shows gap in patient-physician dialogue that may negatively impact patients' quality of life

Endovenous laser treatment can painlessly remove varicose, spider veins

Preventative measures to avoid Lyme disease

Phase 3 study: Tapentadol ER lowers incidence of gastrointestinal adverse events

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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