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20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

A new study from the University of North Carolina at Chapel Hill School of Medicine may have found a way to identify those at greatest risk, thereby allowing doctors to decide who should receive treatment that could save the transplanted organ. The new findings appear in the October issue of the journal Liver Transplantation.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Reflexology popular amongst women receiving chemotherapy

Researchers at Michigan State University are finding that many women who are receiving chemotherapy while in the late stages of breast cancer are turning to a complementary therapy known as reflexology to help them cope.

9 Oct 2005

Minimally invasive needle breast biopsies and sentinel node biopsies should be performed more routinely than they currently are

Physicians should strive to replace traditional, invasive procedures for diagnosing breast cancer with proven, less-invasive diagnostic methods, according to an international panel of breast cancer experts convened at the Keck School of Medicine of the University of Southern California.

9 Oct 2005

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines.

5 Oct 2005

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Subtle differences in other genes -- besides the defective gene known to cause the illness cystic fibrosis -- can significantly modify the inherited disease's severity, a large new multi-center national study has concluded.

5 Oct 2005

Study looks at childrens end-of-life care preferences

Pediatric cancer patients as young as 10 years old who are aware that their disease is incurable have the ability to participate meaningfully in discussions of their own end-of-life care with family members and the health care team, according to investigators at St. Jude Children's Research Hospital and Sydney Children's Hospital.

5 Oct 2005

Cost-effectiveness of potentially life-saving implantable cardioverter defibrillators (ICD) is an important public health issue

The use of implanted defibrillators that keep the heart beating in proper electrical rhythm to prevent cardiac arrest appears to be cost-effective for those patients who receive a significant mortality reduction, according to researchers from Duke Clinical Research Institute (DCRI), Stanford University and the VA Palo Alto Health Care System, Calif. They analyzed eight clinical trials of the devices to arrive at their conclusion.

5 Oct 2005

PET imaging with FDG represents one of the most promising tools for diagnosis of Alzheimer's

Positron emission tomography (PET) imaging--with the radiotracer fluorodeoxyglucose (FDG)--is a promising tool in detecting Alzheimer's disease in patients who have mild cognitive impairment (MCI), according to a study reported in the October issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

5 Oct 2005

Call to stop exposing women to breast cancer risk by needlessly using radiation therapy as a component of Hodgkin disease treatment

Young women who are treated for Hodgkin lymphoma with chest radiation therapy have a high cumulative absolute risk of developing breast cancer later in life. This risk increases with age at end of follow-up, time since diagnosis, and radiation dose, according to a new study in the October 5 issue of the Journal of the National Cancer Institute.

4 Oct 2005

Amiloride and spironolactone may help patients with high blood pressure

Two inexpensive but widely overlooked drugs may help many patients who continue to have high blood pressure despite taking standard blood pressure medications, according to research by Indiana University School of Medicine scientists.

4 Oct 2005

Cancer incidence among women has increased slightly

Overall rates of cancer death for both men and women have declined in the United States, and cancer incidence has remained stable among men. However, overall cancer incidence among women has increased slightly, according to a special article that appears in the October 5 issue of the Journal of the National Cancer Institute.

4 Oct 2005

Americans' risk of dying from cancer continues to decline

The nation's leading cancer organizations report that Americans' risk of dying from cancer continues to decline and that the rate of new cancers is holding steady. The "Annual Report to the Nation on the Status of Cancer, 1975-2002," published in the Oct. 5, 2005, issue of the Journal of the National Cancer Institute, shows observed cancer death rates from all cancers combined dropped 1.1 percent per year from 1993 to 2002.

4 Oct 2005

Hospitalized patients with severe congestive heart failure did not experience a benefit from use of pulmonary artery catheterization

Advances in medical therapy have improved outcomes for many ambulatory patients with heart failure and low ejection fraction (EF; a measure of how much blood the left ventricle of the heart pumps out with each contraction), according to background information in the article.

4 Oct 2005

Researchers identify gene defect in mice that causes cyclical hair loss and skin cancer

Researchers at Jefferson Medical College and at the Wadsworth Center in New York have identified a gene defect in mice resulting in a range of abnormalities, from cyclical hair loss and skin cancer to severe problems in normal skin development.

4 Oct 2005

Evaluation of the efficacy of buprenorphine hydrochloride and clonidine hydrochloride, in detoxification of opioid-dependent teenagers

In a comparison of two drugs prescribed to treat teenagers dependent on heroin and other opioids, the drug buprenorphine was more effective, especially in treatment retention, according to a study in the October issue of Archives of General Psychiatry.

4 Oct 2005

Study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure

Night-time hemodialysis patients may have a greater capacity to repair their hearts and blood vessels compared to those on conventional dialysis three times a week, according to a study in the October issue of the American Journal of Physiology - Renal Physiology, published by the American Physiological Society.

4 Oct 2005

Ischemic brain injury - another promising avenue for stem cell therapy

Adult stem cell therapy quickly and significantly improves recovery of motor function in an animal model for the ischemic brain injury that occurs in about 10 percent of babies with cerebral palsy, researchers report.

4 Oct 2005

Gleevec's uses might expand even further

Gleevec (Imatinib) is a representative of the newest generation of cancer drugs. The substance conveys its potent anti-proliferative effect by selectively supressing the tyrosine kinase pathway. The Giessen lung researchers now issue a first report of this substance as a new target therapy for pulmonary hypertension

4 Oct 2005

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

Heart specialists at Johns Hopkins Heart Institute have been awarded more than $12 million from the National Heart, Lung, and Blood Institute (NHLBI) to study how stem cell therapies can be used to treat hearts damaged by heart attack or heart failure.

4 Oct 2005

Therapy News and Research

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Reflexology popular amongst women receiving chemotherapy

Minimally invasive needle breast biopsies and sentinel node biopsies should be performed more routinely than they currently are

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Study looks at childrens end-of-life care preferences

Cost-effectiveness of potentially life-saving implantable cardioverter defibrillators (ICD) is an important public health issue

PET imaging with FDG represents one of the most promising tools for diagnosis of Alzheimer's

Call to stop exposing women to breast cancer risk by needlessly using radiation therapy as a component of Hodgkin disease treatment

Amiloride and spironolactone may help patients with high blood pressure

Cancer incidence among women has increased slightly

Americans' risk of dying from cancer continues to decline

Hospitalized patients with severe congestive heart failure did not experience a benefit from use of pulmonary artery catheterization

Researchers identify gene defect in mice that causes cyclical hair loss and skin cancer

Evaluation of the efficacy of buprenorphine hydrochloride and clonidine hydrochloride, in detoxification of opioid-dependent teenagers

Study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure

Ischemic brain injury - another promising avenue for stem cell therapy

Gleevec's uses might expand even further

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

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