Bone Marrow News and Research

RSS

Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Bone-targeting radioisotope radium-223 for prostate cancer treatment

The bone-targeting radioisotope radium-223 has delivered promising results in a randomised trial to test its efficacy in treatment of hormone-refractory prostate cancer (HRPC).

5 Jun 2007

Breakthrough in stem cell banking

Scientists from the Research Department of Cryo-Save Group NV together with the University of Cologne (DE) have developed a new scientifically validated method to collect adult mesenchymal stem cells ("MSCs") from the lining of umbilical cord tissue.

1 Jun 2007

Stem cells may look malignant, not act it

Call it the cellular equivalent of big glasses, a funny nose and a fake mustache.

24 May 2007

Patients with myelodysplastic syndromes treated with Revlimid are living longer and remaining transfusion independent

New updated results from a pivotal Phase II trial evaluating Revlimid in patients with an incurable blood cancer known as myelodysplastic syndromes (MDS) were presented by Dr. Alan List, from the H. Lee Moffitt Cancer Center & Research Institute, at the 9th International Symposium on MDS currently taking place in Florence, Italy.

18 May 2007

Scientists develop method to track immune system enzyme in live animals

Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity and B cell tumor development.

18 May 2007

Multiple myeloma dexamethasone / lenalidomide trial closes

The Southwest Oncology Group, the largest of several National Cancer Institute-sponsored clinical trials networks, has permanently closed enrollment in a trial comparing a standard drug therapy, dexamethasone, with a combined therapy of the same drug plus the drug lenalidomide (Revlimid) for people newly diagnosed with multiple myeloma.

16 May 2007

Researchers design cell culture test for assessing a compound's genetic toxicity - cheaper than animal tests

In the daunting marathon that leads to successful drugs, promising drug candidates must pass toxicity tests before entering clinical trials.

15 May 2007

FDA Panel warns anemia drug dangerous for cancer patients

A panel of experts advising the Food and Drug Administration (FDA) in the United States has warned that the popular anemia drug erythropoietin may not be as safe as first thought.

14 May 2007

Adult bone marrow stem cells may help cure certain genetic eye diseases

Scientists have completed a study using mice which showed that bone marrow stem cells can switch roles and produce keratocan, a natural protein involved in the growth of the cornea, the transparent, outer layer of the eyeball.

11 May 2007

It is highly unlikely that older women generate new eggs

Tilly reported the discovery of stem cells capable of migrating from bone marrow to mouse ovaries and generating new eggs there. The research fueled hopes that a new treatment - such as bone marrow transplantation - might one day help older women regain their fertility.

9 May 2007

Hepatitis C infection is associated with an increased risk of non-Hodgkin lymphoma

Hepatitis C infection is associated with an increased risk of non-Hodgkin lymphoma (malignancy involving lymphatic tissue) of 20 percent to 30 percent, and a three-fold increase in the risk of another type of lymphoma, according to a study in the May 9 issue of JAMA.

9 May 2007

Study of fatigue in cancer patients

Fatigue is one of the most common and distressing symptoms cancer patients experience during chemotherapy and radiation treatment, but it's difficult for health care professionals to accurately assess its severity.

4 May 2007

Diesel exhaust fumes affect bone marrow blood flow

A new study finds that exposure to a chemical component of diesel exhaust particles can compromise the ability of resistance arteries to regulate blood flow to bone marrow.

2 May 2007

Researchers identify antioxidant mechanisms involved in protection against heart disease

Zvonimir Katusic, M.D., Ph.D., and Mayo colleagues have identified antioxidant mechanisms essential for regenerative function of endothelial progenitor cells (EPCs).

30 Apr 2007

Small amounts of stem/progenitor cells from bone marrow enhance repair of damaged tissues

New studies in the laboratory of Dr. Darwin J. Prockop, Director of Tulane University's Center for Gene Therapy, are shedding light on the previously mysterious mechanism through which even relatively small amounts of stem/progenitor cells taken from a patient's own bone marrow enhance repair of damaged tissues.

30 Apr 2007