Therapy News and Research

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Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Weight control protein may yield new approaches for treating obesity and type 2 diabetes

The findings in mice further suggest that particular variants of the protein SH2-B might underlie obesity in humans, the researchers said.

16 Aug 2005

Breakthrough in human stem cell research

A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities.

16 Aug 2005

Good news for the hundreds of thousands of cancer patients who undergo radiation therapy

Scientists report that they have a better understanding of the complex effects of radiation on tumor biology and that specific radiation treatment regimens may enhance the effectiveness of radiotherapy, even in tumor populations that have been notoriously difficult to treat.

16 Aug 2005

Chronic use of nitroglycerin for chest pain could lead to mitochondrial damage

Definitive evidence to explain how the drug nitroglycerin relieves chest pain has resulted from a new study by Howard Hughes Medical Institute investigators at Duke University Medical Center. Nitroglycerin relaxes blood vessels to boost blood flow, yet the mechanism by which the drug works has remained a matter of scientific controversy.

16 Aug 2005

Nicotine patch dosage can be adjusted to provide more effective treatment for smokers with a history of alcoholism

Tobacco-caused disease is the leading cause of death for patients with alcoholism, but a study led by The Mayo Clinic Nicotine Dependence Center brings hope to non-depressed, recovering alcoholics who also smoke - individualized nicotine patch therapy. The findings were published in the July issue of Journal of Studies on Alcohol.

15 Aug 2005

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

Researchers from the University of Pittsburgh report the first study to achieve success with gene therapy for the treatment of congenital muscular dystrophy (CMD) in mice, demonstrating that the formidable scientific challenges that have cast doubt on gene therapy ever being feasible for children with muscular dystrophy can be overcome.

15 Aug 2005

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

For people with long-standing rheumatoid arthritis, combined treatment with the new "biologic" drug adalimumab and methotrexate is about five times more effective than methotrexate alone, according to a new systematic review of studies.

15 Aug 2005

Effects of estrogen on heart disease prevention

Researchers at Yale School of Medicine and seven other national institutions are recruiting patients to participate in the Kronos Early Estrogen Prevention Study (KEEPS) to look at the effects of estrogen on heart disease prevention.

15 Aug 2005

Experimental therapy could offer new way to treat spine damage

An experimental therapy that combines stem cells and gene therapy to repair spinal cord injuries in rats may lead to a new way to treat the same injury in humans.

15 Aug 2005

New study shows testosterone treatment linked to prostate cancer

Researchers in the United States say that prostate cancer developed in 20 men within months to a few years after they began testosterone supplementation, to correct a deficiency of the hormone.

15 Aug 2005

Lung cancer cure possible with early screening

Recent reports in the media of the deaths of well known people from lung cancer and the surprising news that Dana Reeve, the non-smoking wife of the late Christopher Reeve has the disease, has re-ignited concerns about the so-called 'silent killer', lung cancer.

15 Aug 2005

Calcium fights prostate cancer

Calcium, more familiar in its role as one of the building blocks of the body, is being enlisted as a tool in the fight against prostate cancer.

15 Aug 2005

Combined gene therapy eliminates glioblastoma multiforme in lab studies

Despite aggressive treatment, glioblastoma multiforme (GBM) - the most common and deadly of brain cancers - usually claims the lives of its victims within six to 12 months of diagnosis. Because GBM is so aggressive, the disease has been the target of a number of laboratory and clinical studies investigating the effectiveness of gene therapy to deliver novel therapies to the brain.

15 Aug 2005

Activated Stat5 protein in prostate cancer can predict outcome, may help target treatment

Researchers from Lombardi Comprehensive Cancer Center at Georgetown University found that testing for an activated Stat5 protein in prostate tumor tissue effectively predicts which men have a form of prostate cancer that may become more aggressive and life threatening.

15 Aug 2005

Scientists say valproic acid can eradicate dormant HIV

Early research by scientists in the U.S. suggests that valproic acid could be a potential way to eradicate dormant HIV infections.

14 Aug 2005

New gene technique useful for identifying genes and drug targets for diseases such as cancers and diabetes

A collaborative project between American and Chinese researchers developed a way to study the function of genes in mice and man by using a moveable genetic element from moths, according to a report in the journal Cell.

13 Aug 2005

How negatively charged lipids stick to negatively charged DNA and self-organize into structures

Scientists studying the structure and interaction of negatively charged lipids and DNA molecules have created a "cookbook" for a class of nontoxic DNA delivery systems that will assist doctors and clinicians in the safe and effective delivery of genetic medicine.

13 Aug 2005

Infusion nurses examine need for standards of practice in immunoglobulin therapy

A review article published in the July/August 2005 Journal of Infusion Nursing examines the need for established treatment guidelines to support doctors and nurses in correctly dosing and administering intravenous immunoglobulin (IVIG) as replacement therapy in patients with primary immunodeficiency (PI) disorders, who do not produce adequate levels of antibodies essential in fighting infectious diseases.

13 Aug 2005

Findings could lead to gene therapy cure for childhood blindness

In findings that could lead to curing some forms of congenital blindness through gene therapy, researchers at UCLA have discovered that RPE65, a gene missing in infants born with the blinding disease Leber congenital amaurosis, is also a key enzyme in the visual cycle. The identity of this enzyme has long been a mystery to scientists.

11 Aug 2005

Therapy News and Research

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Weight control protein may yield new approaches for treating obesity and type 2 diabetes

Breakthrough in human stem cell research

Good news for the hundreds of thousands of cancer patients who undergo radiation therapy

Chronic use of nitroglycerin for chest pain could lead to mitochondrial damage

Nicotine patch dosage can be adjusted to provide more effective treatment for smokers with a history of alcoholism

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

Effects of estrogen on heart disease prevention

Experimental therapy could offer new way to treat spine damage

New study shows testosterone treatment linked to prostate cancer

Lung cancer cure possible with early screening

Calcium fights prostate cancer

Combined gene therapy eliminates glioblastoma multiforme in lab studies

Activated Stat5 protein in prostate cancer can predict outcome, may help target treatment

Scientists say valproic acid can eradicate dormant HIV

New gene technique useful for identifying genes and drug targets for diseases such as cancers and diabetes

How negatively charged lipids stick to negatively charged DNA and self-organize into structures

Infusion nurses examine need for standards of practice in immunoglobulin therapy

Findings could lead to gene therapy cure for childhood blindness

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