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Spinal arthritis often overlooked in children

When kids or teens experience aching joints and stiffness it may be more than growing pains. It may be arthritis of the spine and other joints (ankylosing spondylitis), which researchers report can often go undiagnosed for years and years, leading to serious problems in adulthood.

15 Jun 2005

Nanotechnology used to smuggle a powerful chemotherapeutic drug inside tumor cells

University of Michigan scientists have created the nanotechnology equivalent of a Trojan horse to smuggle a powerful chemotherapeutic drug inside tumor cells - increasing the drug's cancer-killing activity and reducing its toxic side effects.

15 Jun 2005

Orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents

When combined with diet, exercise and behavioral therapy, orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents, compared with placebo, according to an article in the June 15 issue of JAMA: The Journal of the American Medical Association.

14 Jun 2005

Research urges a new approach to cancer detection

A few years ago, Medhat Osman, M.D., Ph.D., had a patient who was scanned due to a suspicion of lung cancer using positron emission tomography (PET) and computer tomography (CT) technology. The scan came back negative, but the patient then complained of a problem with his leg.

14 Jun 2005

Two common gene variations are associated with the risk for developing chronic kidney disease

Two common gene variations are associated with the risk for developing chronic kidney disease, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions. One variant increases risk and the other decreases risk with a similar effect in whites, African-Americans, diabetic and non-diabetic individuals.

14 Jun 2005

Tetanus toxin may help fight depression, anxiety, anorexia and Parkinson's

A team of researchers from the Department of Biochemistry and Molecular Biology and the Institute of Neuroscience at the Universitat Autònoma de Barcelona has discovered that tetanus toxin, which causes tetanus, could be extremely useful as a therapy against psychological disorders such as depression, anxiety and anorexia, and to slow the progress of neurodegenerative disorders such as Parkinson's disease.

14 Jun 2005

Invasive treatment including stenting may be more effective for heart attack patients who arrive late at hospital

Invasive treatment including stenting may have better outcomes than conventional treatments for heart attack patients who arrive at the hospital more than 12 hours after symptoms began, according to a study in the June 15 issue of JAMA.

14 Jun 2005

Fish oil does not lower risk of serious heart rhythm abnormalities for patients with implantable defibrillators

Even though previous research has shown that fatty acids from fish oil reduce the risk of sudden cardiac death, patients with implantable defibrillators who took fish oil supplements did not see a reduction in serious heart rhythm abnormalities, according to a study in the June 15 issue of JAMA: The Journal of the American Medical Association.

14 Jun 2005

Study reveals benefits of using insulin earlier

Results of an all-Canadian study announced June 13 at an international diabetes congress demonstrate that patients with type 2 diabetes can safely achieve target blood sugar (glycemic) levels faster and more frequently when insulin glargine (a basal, long-acting insulin) is added to therapy, versus using oral agents alone.

14 Jun 2005

Causes, consequences and clinical implications of alcohol-related brain shrinkage

Previous studies have demonstrated that the brains of alcoholics are smaller, lighter and "shrunken" when compared to nonalcoholic brains.

14 Jun 2005

FDA grants Vical orphan-drug designation

Vical Incorporated today announced that the Office of Orphan Products Development of the U.S. Food and Drug Administration (FDA) has designated the company's bivalent (two-plasmid) formulation of the company's vaccine against cytomegalovirus (CMV) as an orphan drug for the prevention of clinically significant CMV viremia, CMV disease and associated complications in at-risk hematopoietic cell transplant (HCT) and solid organ transplant (SOT) populations.

14 Jun 2005

Non-profit public-private partnership develops affordable, new drug regimens for tuberculosis

The Global Alliance for TB Drug Development (TB Alliance), a non-profit public-private partnership developing affordable, new drug regimens for tuberculosis, today announced the start of Phase I clinical trials for the lead TB drug in its pipeline, PA-824. The trials begin this month.

14 Jun 2005

Viagra helps children with heart-lung condition achieve improved quality of life

Viagra, a drug originally developed to treat heart disease, and now more commonly used to treat impotence, may also help children with a serious heart-lung condition to walk further and breathe more easily.

14 Jun 2005

Doppler imaging provides better understanding of muscular dystrophy

A new study presented this week at the American Society of Echocardiography's 16th Annual Scientific Sessions offers new hope to children stricken with Duchene muscular dystrophy (DMD), a degenerative muscular disease characterized by a loss of voluntary muscle control which can eventually affect the heart.

14 Jun 2005

Study examines reasons for unsatisfactory outcomes following deep brain stimulation surgery

A study of follow-up care for patients with unsatisfactory outcomes from deep brain stimulation (DBS) surgery for movement disorders offers insights into reasons for problems and proposes strategies for improved outcomes. The study will appear in the August print issue of Archives of Neurology.

13 Jun 2005

Overweight and obese women with breast cancer may be undertreated

Overweight and obese women with breast cancer may receive reduced doses of chemotherapy drugs, which may put them at greater risk of cancer recurrence, according to a study in the June 13 issue of Archives of Internal Medicine.

13 Jun 2005

For men diagnosed with prostate cancer, there is no risk of recurrence if external beam radiation therapy (EBRT) is delayed by several months

A study published in the July 15, 2005 issue of CANCER, a peer-reviewed journal of the American Cancer Society, finds delays of EBRT had no harmful impact on clinical outcome or biochemical marker levels in low-, intermediate- and high-risk patients.

13 Jun 2005

Research accelerates the search for an effective cancer vaccine

By devising a novel way to package the genome of a common human tumor virus - the virus that causes common warts, genital warts and that is implicated in prevalent cancers - scientists have paved the way for making the pathogen far more accessible to biomedical science.

13 Jun 2005

Short-term use of CPAP therapy may protect against cardiovascular disease

A common sleep therapy used to treat patients with obstructive sleep apnea (OSA) may actually have a protective effect against death related to cardiovascular disease.

13 Jun 2005

Women in the UK most anxious about breast cancer

A new survey has found that one in three British women would be willing to have both breasts removed if they thought they were at high risk of breast cancer.

13 Jun 2005

Therapy News and Research

Spinal arthritis often overlooked in children

Nanotechnology used to smuggle a powerful chemotherapeutic drug inside tumor cells

Orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents

Research urges a new approach to cancer detection

Two common gene variations are associated with the risk for developing chronic kidney disease

Tetanus toxin may help fight depression, anxiety, anorexia and Parkinson's

Invasive treatment including stenting may be more effective for heart attack patients who arrive late at hospital

Fish oil does not lower risk of serious heart rhythm abnormalities for patients with implantable defibrillators

Study reveals benefits of using insulin earlier

Causes, consequences and clinical implications of alcohol-related brain shrinkage

FDA grants Vical orphan-drug designation

Non-profit public-private partnership develops affordable, new drug regimens for tuberculosis

Viagra helps children with heart-lung condition achieve improved quality of life

Doppler imaging provides better understanding of muscular dystrophy

Study examines reasons for unsatisfactory outcomes following deep brain stimulation surgery

Overweight and obese women with breast cancer may be undertreated

For men diagnosed with prostate cancer, there is no risk of recurrence if external beam radiation therapy (EBRT) is delayed by several months

Research accelerates the search for an effective cancer vaccine

Short-term use of CPAP therapy may protect against cardiovascular disease

Women in the UK most anxious about breast cancer

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