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Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

A research team from Spain has prepared a Cochrane systematic review that explores the efficacy, safety, and adherence to fixed-dose combinations (FDCs) of drugs versus single-drug formulations to treat people who are newly diagnosed with tuberculosis (TB).

23 May 2016

Inhibiting palmitate-adding enzyme can make cancer cells sensitive to EGFR inhibitors

The mistaken activation of certain cell-surface receptors contributes to a variety of human cancers. Knowing more about the activation process has led researchers to be able to induce greater vulnerability by cancer cells to an existing first-line treatment for cancers (mainly lung) driven by a receptor called EGFR.

23 May 2016

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Doctors worried about dangerous blood clots in patients undergoing a coronary artery procedure— such as angioplasty to treat a heart attack — will often administer antiplatelet therapy to head off complications.

22 May 2016

New collaborative research center to investigate promising aspects of mucosal immunology

Immunology - and the idea that many diseases can best be addressed by boosting the body's own immune response - is one of the hottest areas in medical research and clinical treatment.

22 May 2016

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

For cancer to spread, the cells that take off into the bloodstream must find a tissue that will permit them to thrive. They don't just go looking, though. Instead, they actively prepare the tissue, in one case by co-opting a protein that suppresses defenses the body would otherwise mount.

21 May 2016

Research provides pathway toward creation of first broad-spectrum antiviral drug

By studying the rare person -- about one in a million -- who can fight off viral infections more effectively than everyone else, investigators at the Icahn School of Medicine at Mount Sinai have developed a strategy to help the rest of us achieve this enhanced anti-viral state.

21 May 2016

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Intensive therapies to reduce high blood pressure can cut the risk of heart disease in older adults without increasing the risk for falls, according to doctors at Wake Forest Baptist Medical Center.

21 May 2016

GMU’s early-detection urine test works for Lyme disease, study shows

After three years and 300 patients, George Mason University researchers have proof that their early-detection urine test for Lyme disease works.

21 May 2016

New experimental model may predict eventual cardiac phenotype in pediatric patients

An experimental model uses genetics-guided biomechanics and patient-derived stem cells to predict what type of inherited heart defect a child will develop, according to authors of a new study in the journal Cell.

21 May 2016

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects.

21 May 2016

SPRINT supports stringent BP goals for elderly

Analysis of SPRINT participants older than 75 years shows that they too benefitted from an intensive blood pressure target of 120 mmHg.

20 May 2016

Novel protective gene against CAD uncovered

A large study has found that mutations in the gene encoding the major subunit of the asialoglycoprotein receptor are protective against coronary artery disease.

20 May 2016

Specific monocyte immune cells serve as link between gut bacteria and the brain

A special kind of immune cell serves as an intermediary between gut bacteria and the brain. Dr. Susanne Wolf of the Max Delbruck Center for Molecular Medicine in the Helmholtz Association discovered this in tests on mice and published her findings in the journal Cell Reports.

20 May 2016

High levels of p62 protein in liver linked to cancer recurrence

Researchers at University of California San Diego School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have discovered that high levels of the protein p62 in human liver samples are strongly associated with cancer recurrence and reduced patient survival.

20 May 2016

NS5 viral protein could be promising vaccine target against Zika virus

A viral protein known as NS5 is a promising target for vaccines against Zika and related viruses, according to National Institutes of Health scientists and colleagues at Mount Sinai's Icahn School of Medicine.

20 May 2016

Breakthrough technique removes potentially harmful additives from common injectable drugs

Bring the drugs, hold the suds. That summarizes a promising new drug-making technique designed to reduce serious allergic reactions and other side effects from anti-cancer medicine, testosterone and other drugs that are administered with a needle.

20 May 2016

International Clinical Trials Day: University of Sheffield welcomes public participation

Leading researchers from Sheffield Teaching Hospitals and the University of Sheffield will be providing an insight into some of their work as part of International Clinical Trials Day.

20 May 2016

New research looks at conversations that take place among selected parenting groups on Facebook

A study of conversations among pregnant women and new mothers on Facebook has highlighted a need for health professionals to provide clear direction on where new parents and pregnant women can access reliable and evidence based information about medicines.

20 May 2016

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

In a new study using mice and lab-grown human cells, a scientific team led by Johns Hopkins Kimmel Cancer Center researchers show how a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth.

20 May 2016

PYY hormone may offer effective treatment for type 2 diabetes

Researchers at the Norwegian University of Science and Technology and Oxford University have found a hormone that may offer an effective treatment for type 2 diabetes.

20 May 2016

Medicine News and Research

Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

Inhibiting palmitate-adding enzyme can make cancer cells sensitive to EGFR inhibitors

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

New collaborative research center to investigate promising aspects of mucosal immunology

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

Research provides pathway toward creation of first broad-spectrum antiviral drug

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

GMU’s early-detection urine test works for Lyme disease, study shows

New experimental model may predict eventual cardiac phenotype in pediatric patients

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

SPRINT supports stringent BP goals for elderly

Novel protective gene against CAD uncovered

Specific monocyte immune cells serve as link between gut bacteria and the brain

High levels of p62 protein in liver linked to cancer recurrence

NS5 viral protein could be promising vaccine target against Zika virus

Breakthrough technique removes potentially harmful additives from common injectable drugs

International Clinical Trials Day: University of Sheffield welcomes public participation

New research looks at conversations that take place among selected parenting groups on Facebook

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

PYY hormone may offer effective treatment for type 2 diabetes

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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