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Pharmacogenomics used to treat inherited kidney disorder of children

Mayo Clinic researchers have used pharmacogenomics to develop a test and treatment for an inherited kidney disorder that can cause organ failure in children and young adults.

4 May 2005

New study confirms 'wait and see' approach best for some prostate cancers

Men diagnosed with low-grade localized prostate cancer who opt not to undergo aggressive treatment for the disease are unlikely to die of the disease, even after 20 years, according to researchers in Connecticut.

4 May 2005

Psychological treatment most effective treatment for pediatric obsessive-compulsive disorder

Psychological treatment that teaches children to face their fears is the most effective treatment for pediatric obsessive-compulsive disorder (OCD), according to a new Mayo Clinic analysis of previously published research.

4 May 2005

Glucose byproduct prevents brain damage after diabetic coma

A natural, non-toxic byproduct of glucose may prevent brain cell death and cognitive impairment in diabetics following an episode of severely low blood sugar, according to researchers at the San Francisco VA Medical Center (SFVAMC).

4 May 2005

Diabetes appears to rob women of usual advantage in heart disease risk

For men, a heart attack increases the risk of dying from coronary heart disease more than diabetes does, but for women, diabetes is sometimes the greater threat, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

MRI study shows hormone leptin alters brains, may ease cravings of people with obesity gene

A magnetic resonance imaging (MRI) study finds that the protein hormone leptin promotes development of gray matter in the part of the brain that regulates cravings and the ability to monitor personal behavior.

4 May 2005

$Black women at less risk of fractures$

Black women at less risk of fractures

A recent report from the U.S. surgeon general on bone health and osteoporosis has found that black women have a lower risk of fracture than white women at every level of bone mineral density.

3 May 2005

Study identifies possible marker for efficacy of gefitinib in lung cancer patients

Patients with advanced non–small-cell lung cancer (NSCLC) whose tumor cells contain extra copies of the epidermal growth factor receptor (EGFR) gene may be more likely to respond to the drug gefitinib (Iressa), and this high gene copy number may be an effective predictor of gefitinib efficacy, according to a new study in the May 4 issue of the Journal of the National Cancer Institute.

3 May 2005

Long-term outcomes promising for patients with localized, low-grade prostate cancer

A study that includes 20 years of follow-up does not support aggressive treatment for localized, low-grade prostate cancer, with data indicating a small risk of progression of this grade of cancer, according to a study in the May 4 issue of JAMA.

3 May 2005

Researchers have successfully induced adult heart-muscle cells to divide and multiply

In the best documented effort to date, researchers from the Howard Hughes Medical Institute at Children's Hospital Boston and Harvard Medical School have successfully induced adult heart-muscle cells to divide and multiply.

3 May 2005

Alarms better than medication for stopping bedwetting

Alarms that buzz, ring or light up when a child wets the bed are more effective at stopping bedwetting than medications like the drug commonly used to prevent urination, according to a new review of recent studies.

2 May 2005

Glaucoma therapy patients often do not comply with their doctor’s prescribed medicine regimen

A study that appears in the May edition of Ophthalmology, the clinical journal of the American Academy of Ophthalmology, shows that as many as 47 percent of patients receiving glaucoma therapy do not comply with their doctor’s prescribed medicine regimen. This is in startling contrast to the 90 percent of doctors who believe that their patients are following the prescribed treatment.

2 May 2005

Giving children access to drug clinical trials is crucial, clofarabine approval shows

The accelerated approval of the drug clofarabine to treat relapsed or refractory pediatric acute lymphoblastic leukemia (ALL) demonstrates the importance of offering children rapid access to new treatments through clinical trials, according to investigators at St. Jude Children's Research Hospital. Refractory or relapsed ALL is a disease that resists treatment.

2 May 2005

Small number of genes can predict response to chronic hepatitis C therapy

For the first time, physicians at University Health Network and University of Toronto have identified a small subset of genes that can predict whether a patient with chronic Hepatitis C will be able to respond to current treatments.

2 May 2005

Antidepressant medication or psychotherapy may be effective in treating chronically depressed patients when the other is not

Switching from an antidepressant medication to psychotherapy or vice versa may improve symptoms in chronically depressed patients who prove unresponsive to their initial treatment, according to an article in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 May 2005

HIV treatment not affected by hormonal birth control

Estrogen and progesterone hormones in birth control do not influence the effectiveness of highly active antiretroviral therapy (HAART), which is used to treat HIV infection, according to researchers from the Johns Hopkins Bloomberg School of Public Health and other institutions. The study is published in the May 1, 2005, issue of the American Journal of Epidemiology.

2 May 2005

Fusing physics with medicine to fight cancer

Everyone’s lives are touched by cancer - it is a disease that affects 1 in 3 of us throughout our lifetime. Future developments that lead to earlier diagnosis and more effective therapy lie in further successful collaboration between high energy physicists and the healthcare industry.

2 May 2005

HRT now linked to cancer of the womb

A new study of more than 700,000 women has found, say the researchers, that Hormone replacement therapy (HRT) can increase the risk of cancer of the womb, depending on the form of HRT used.

1 May 2005

New prognostic markers help identify risk of relapse

A recently completed clinical study has found new prognostic markers that may help clinicians identify those children with leukaemia who are at high risk of relapse and are most in need of intensified treatment to improve their chance of survival.

1 May 2005

Lower vaccination rates put children at risk

A study done in part by the University of Alberta shows that children treated with complementary and alternative medicine (CAM) have lower vaccination rates than the general population, exposing them to added risk from preventable illnesses such as mumps and measles.

1 May 2005

Therapy News and Research

Pharmacogenomics used to treat inherited kidney disorder of children

New study confirms 'wait and see' approach best for some prostate cancers

Psychological treatment most effective treatment for pediatric obsessive-compulsive disorder

Glucose byproduct prevents brain damage after diabetic coma

Diabetes appears to rob women of usual advantage in heart disease risk

MRI study shows hormone leptin alters brains, may ease cravings of people with obesity gene

Black women at less risk of fractures

Study identifies possible marker for efficacy of gefitinib in lung cancer patients

Long-term outcomes promising for patients with localized, low-grade prostate cancer

Researchers have successfully induced adult heart-muscle cells to divide and multiply

Alarms better than medication for stopping bedwetting

Glaucoma therapy patients often do not comply with their doctor’s prescribed medicine regimen

Giving children access to drug clinical trials is crucial, clofarabine approval shows

Small number of genes can predict response to chronic hepatitis C therapy

Antidepressant medication or psychotherapy may be effective in treating chronically depressed patients when the other is not

HIV treatment not affected by hormonal birth control

Fusing physics with medicine to fight cancer

HRT now linked to cancer of the womb

New prognostic markers help identify risk of relapse

Lower vaccination rates put children at risk

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