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Researchers find ovarian cancer patients who appear to respond better than others to gefitinib, or Iressa

Researchers at Fox Chase Cancer Center in Philadelphia have identified a subset of ovarian cancer patients who appear to respond better than others to gefitinib, or Iressa. The research was presented today at the 96th Annual Meeting of the American Association for Cancer Research in Anaheim, Calif.

20 Apr 2005

Heart attack victims face increased risk of death with Natrecor

In a recent study Jonathan Sackner-Bernstein, a doctor at North Shore University Hospital in New York says that Natrecor, heart failure treatment produced by drug company Johnson & Johnson may be linked to a greater risk of death when compared with standard therapy.

20 Apr 2005

New era drug gives hope to Gleevec resistant leukaemia sufferers

Gleevec, a drug regarded by many as having "wonder drug" capabilities in the treatment of chronic myelogenous leukaemia (CML) and other cancers, has been revealed as having shortcomings in that some patients have undergone a relapse after building a resistance to the drug. For others with the advanced stage of the disease, the drug has failed to produce durable remissions.

19 Apr 2005

Combination chemotherapy shows small survival benefit in advanced stomach cancer

Patients with advanced stomach cancer have the best chance of prolonging their survival with a combination of chemotherapies instead of just one, according to a new review of previous studies.

19 Apr 2005

Researchers find promising cancer-fighting power of synthetic cell-signaling molecule

Novel anti-cancer compounds called Enigmols suppress the growth of human cell lines representing cancers of the prostate, breast, colon, ovary, pancreas, brain and blood, and reduce tumors in three animal studies, new research shows.

19 Apr 2005

Researchers insert engineered human stem cells into the spinal cords of ALS-afflicted rats

Unveiling a delivery method that may one day help surgeons treat the deadly neurodegenerative disease amyotrophic lateral sclerosis (ALS), researchers at the University of Wisconsin-Madison have inserted engineered human stem cells into the spinal cords of ALS-afflicted rats.

19 Apr 2005

Call for a United States Global Health Service

The federal government should create and fund an umbrella organization called the United States Global Health Service (GHS) to mobilize the nation's best health care professionals and other experts to help combat HIV/AIDS in hard-hit African, Caribbean, and Southeast Asian countries, says a new report from the Institute of Medicine of the National Academies.

19 Apr 2005

Drugs targeted at muscle cells can be of use in the treatment of diabetes patients with insulin resistance

Type 2 diabetes is a clinical disease characterised by disruption to the metabolism of glucose and lipids as well as to the production of and physiological reactions to insulin.

19 Apr 2005

Compound derived from cottonseed oil could help improve the effectiveness of chemotherapy at treating head and neck cancer

The findings, which will be presented Tuesday, April 19, at the American Association for Cancer Research annual meeting, could lead to a treatment that provides an effective option to surgically removing the cancer, helping patients preserve vital organs involved in speech and swallowing.

19 Apr 2005

Clinical trial of gefitinib for advanced lung cancer closes early

Researchers have closed a randomized clinical trial comparing gefitinib (Iressa) vs. placebo following chemotherapy and radiation for patients with non-small cell lung cancer (NSCLC) that had spread only to nearby tissues or lymph nodes. Review of interim data indicated that gefitinib would not improve survival.

19 Apr 2005

Family history of obesity increases risk of suffering a serious heart ailment

A Johns Hopkins study finds that people who have a family history of heart disease have more reason than most to keep their weight down. In these families, the Hopkins team found that siblings who were obese or overweight had a 60 percent increased risk of suffering a serious heart ailment, such as a heart attack, before the age of 60.

19 Apr 2005

Gene expression pattern predicts multiple drug resistance

St. Jude Children's Research Hospital discovery of genetic links to multi-drug resistance gives clinicians new insight into the cause of treatment failure and suggests targets for novel anti-leukemic drugs

19 Apr 2005

Plastic surgeons caution against unknown dangers of mesotherapy

The allure of shedding unwanted pockets of fat with a series of simple injections, known as mesotherapy, sounds too good to be true - and it just might be. According to an ASPS Device & Technique Assessment (DATA) Committee report published in the April 15 issue of Plastic and Reconstructive Surgery® (PRS), the official medical journal of the American Society of Plastic Surgeons (ASPS), patients should be wary of mesotherapy until the safety and effectiveness of the procedure are confirmed.

19 Apr 2005

New approach to fighting cancer, based on nanoscale particles

Researchers at Rice University in Texas have developed a new approach to fighting cancer, based on nanoscale particles that can both detect and destroy cancerous cells. The report appears in the April 13 issue of the American Chemical Society's journal Nano Letters.

13 Apr 2005

Clinical diagnosis of Alzheimer's may be delayed

In a study of people with mild cognitive impairment (MCI), those who took the drug donepezil were at reduced risk of progressing to a diagnosis of Alzheimer's disease (AD) during the first year of the trial, but by the end of the 3-year study there was no benefit from the drug. Vitamin E was also tested in the study and was found to have no effect at any time point in the study when compared with placebo.

13 Apr 2005

Scientists use transcription factors to increase insulin production in diabetic mice

A group of Japanese scientists has used gene therapy to deliver three insulin transcription factors, MafA, PDX-1, and NeuroD, to the livers of diabetic mice. As a result, the mice experienced an increase in insulin gene expression and insulin production, raising the possibility that this could eventually be used to treat diabetes.

13 Apr 2005

Scientists identifiy protein that seems to control the malignant features of brain tumor cells

Scientists from Wake Forest University School of Medicine have identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. The research is reported in the current issue of Molecular Cancer Research.

13 Apr 2005

Technology helps Stanford shed new light on coronary bypass surgery

On March 31, Joel Dyels celebrated his 72nd birthday by having coronary bypass surgery at Stanford Hospital. He also became the third patient at Stanford - and in the United States - to benefit from a new imaging system that lets doctors see the blood pathways they have created while the patient's chest is still open.

12 Apr 2005

Drug that reduces the pain of fibromyalgia and improves sleep

A study of a drug that reduces the pain of fibromyalgia and improves sleep is published by a University of Kentucky physician in the peer-reviewed journal, Arthritis & Rheumatism.

12 Apr 2005

New medical uses for the Kunjin virus

Queensland Government scientists at the Department of Health Services have collaborated with scientists at the University of Queensland (UQ) and The Queensland Institute of Medical Research (QIMR) to discover new medical uses for the Kunjin virus.

12 Apr 2005

Therapy News and Research

Researchers find ovarian cancer patients who appear to respond better than others to gefitinib, or Iressa

Heart attack victims face increased risk of death with Natrecor

New era drug gives hope to Gleevec resistant leukaemia sufferers

Combination chemotherapy shows small survival benefit in advanced stomach cancer

Researchers find promising cancer-fighting power of synthetic cell-signaling molecule

Researchers insert engineered human stem cells into the spinal cords of ALS-afflicted rats

Call for a United States Global Health Service

Drugs targeted at muscle cells can be of use in the treatment of diabetes patients with insulin resistance

Compound derived from cottonseed oil could help improve the effectiveness of chemotherapy at treating head and neck cancer

Clinical trial of gefitinib for advanced lung cancer closes early

Family history of obesity increases risk of suffering a serious heart ailment

Gene expression pattern predicts multiple drug resistance

Plastic surgeons caution against unknown dangers of mesotherapy

New approach to fighting cancer, based on nanoscale particles

Clinical diagnosis of Alzheimer's may be delayed

Scientists use transcription factors to increase insulin production in diabetic mice

Scientists identifiy protein that seems to control the malignant features of brain tumor cells

Technology helps Stanford shed new light on coronary bypass surgery

Drug that reduces the pain of fibromyalgia and improves sleep

New medical uses for the Kunjin virus

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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