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Modest triglyceride elevations linked to coronary artery disease risk

Even modest increases in blood levels of triglycerides, as well as a type of high cholesterol known as type III hyperlipidemia, are strongly associated with coronary artery disease in people with a family history of the disease, according to a new study in the April 5, 2005, issue of the Journal of the American College of Cardiology.

5 Apr 2005

Gene therapy shows effect in heart patients

The first double-blind, placebo-controlled randomized trial of VEGF gene injections into the heart muscle of patients with coronary artery disease with the intention of spurring growth of new blood vessels showed significant effects on heart wall motion, although blood flow was not significantly better in treated patients, according to a new study in the April 5, 2005, issue of the Journal of the American College of Cardiology.

5 Apr 2005

Cognitive therapy to treat moderate to severe depression works just as well as antidepressants

The study, conducted by researchers at the University of Pennsylvania and Vanderbilt University, challenges the American Psychiatric Association guidelines that antidepressant medications are the only effective treatment for moderately to severely depressed patients.

5 Apr 2005

Studies examine menopausal hormone therapy and risk of breast cancer recurrence

The doses of estrogen and progestogen used in menopausal hormone therapy may be related to the risk of breast cancer recurrence, according to a new study in the April 6 issue of the Journal of the National Cancer Institute.

5 Apr 2005

Important trial in the fight against lung cancer

Two University of Kentucky researchers continue their work with a vaccine to prevent lung cancer recurrences in patients following primary treatment of the disease.

5 Apr 2005

Method of gene therapy accurately corrects mutations in disease-causing genes

Harnessing the strength of a natural process that repairs damage to the human genome, a researcher from UT Southwestern Medical Center has helped establish a method of gene therapy that can accurately and permanently correct mutations in disease-causing genes.

5 Apr 2005

Promising new therapy that prompts the immune system to aid in the fight against melanoma tumors

Melanoma is a particularly deadly form of skin cancer very resistant to treatment. Researchers at H. Lee Moffitt Cancer Center & Research Institute and the University of South Florida are testing a promising new therapy that prompts the immune system to aid in the fight against melanoma tumors.

5 Apr 2005

Weight loss surgery is the most effective treatment available for obesity say experts

A panel of experts charged with reviewing all the available evidence on morbid obesity and weight loss surgery today concluded weight loss surgery is the most effective treatment available and can result in the improvement or complete resolution of diseases associated with obesity, according to a consensus statement published in the April edition of the Journal of the American College of Surgeons (JACS).

5 Apr 2005

DNA repair kit announced by scientists

A study by scientists at Sangamo BioSciences, Inc. has demonstrated the use of the Company's zinc finger DNA-binding protein (ZFP) technology to achieve highly efficient, permanent correction of a disease-causing gene in primary human cells.

5 Apr 2005

Canada spends more on stem cell research

Canadian Justice Minister Irwin Cotler gave Canadian stem cell research an extra boost with the announcement of $5.3 million in annual funding.

5 Apr 2005

New report shows therapy as effective as drugs for depression

In a surprising report from the University of Pennsylvania, researchers are suggesting that, contrary to current American Psychiatric Association (APA) guidelines, psychological therapy and counselling can be just as effective as drugs in the early stages of treating moderate to severe depression.

4 Apr 2005

Method of gene therapy that can accurately and permanently correct mutations in disease-causing genes

4 Apr 2005

Light therapy effectively treats mood disorders

A study commissioned by the American Psychiatric Association and led by a psychiatrist at the University of North Carolina at Chapel Hill School of Medicine has found that light therapy effectively treats mood disorders, including seasonal affective disorder (SAD) and other depressive disorders.

4 Apr 2005

Step toward a potential treatment for Huntington's disease

Researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine have taken another step toward a potential treatment for Huntington's disease (HD). Using an approach called RNA interference (RNAi), the scientists reduced levels of the disease-causing HD protein in mice and significantly improved the movement and neurological abnormalities normally associated with the disease.

4 Apr 2005

Newer imaging technologies may lead to over treatment

Newer imaging technologies allow physicians to visualize more of the arteries in the lungs, including detecting small blood clots not previously seen, but seeing more may have little impact on the patient’s outcome, a new study suggests.

4 Apr 2005

Why smokers lung is resistant to steroid treatment

UK researchers think they are close to finding the first effective treatment to fight one of the biggest killer diseases in the UK. Professor Peter Barnes will present the work at the British Endocrine Societies 2005 meeting in Harrogate.

4 Apr 2005

Tarvacin shows significant anti-viral activity

Peregrine Pharmaceuticals today announced that there will be two presentations, April 4 and 6, at the American Association of Immunologists (AAI) annual meeting in San Diego, California, indicating the anti-viral potential of its Tarvacin antibody. Dr. Melina Soares of The University of Texas Southwestern Medical Center at Dallas will present pre-clinical data titled "Targeting inside-out phospholipids on viruses in a guinea pig model of Lassa fever."

4 Apr 2005

Cognitive therapy may be as effective as antidepressant medications in the initial treatment of moderate to severe major depression

Cognitive therapy, when provided by an experienced therapist, may be as effective as antidepressant medications in the initial treatment of moderate to severe major depression, according to an article in the April issue of Archives of General Psychiatry.

4 Apr 2005

Men who are treated for prostate cancer with radiation may have almost doubled their risk of developing rectal cancer

A study in the American Gastroenterological Association (AGA) journal Gastroenterology has found that men who are treated for prostate cancer with radiation may have almost doubled their risk of developing rectal cancer when compared to men who opted to have surgery.

4 Apr 2005

New once a day asthma treatment approved by FDA

More than 5,000 people die from asthma each year in the United States. Although asthma deaths are infrequent, they have increased significantly during the last two decades.

4 Apr 2005