Antigen News and Research

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Study identifies regions of genes linked to Beh-et's disease

Researchers don't know the exact cause of Beh-et's disease, a chronic condition that leads to oral and genital sores and serious complications such as blindness, but new research brings better understanding to what makes some people more susceptible to being affected.

16 Feb 2013

Allografts better survive implantation into brains of immunocompetent research mice

Researchers at the Johns Hopkins University in Baltimore, Md., and the Mossakowski Medical Research Centre in Warsaw, Poland, have found that nonself-donated cells (allografts) better survive implantation into the brains of immunocompetent research mice when the grafts are injected into the striatum (STR) of the brain rather than injected into the forceps minor (FM) region.

14 Feb 2013

Antibody therapeutics targeting GPCRs to be developed by alliance between MorphoSys and Heptares

MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) and UK-based Heptares Therapeutics, the leading GPCR drug discovery and development company, have signed an agreement to discover novel antibody therapeutics targeting G protein-coupled receptors (GPCRs), which are membrane proteins involved in a broad range of biological processes and diseases.

13 Feb 2013

Metastatic renal cell carcinoma (mRCC) therapy: an interview with Charles A. Nicolette, Ph.D., CSO of Argos Therapeutics

Metastatic renal cell carcinoma is a devastating disease. There are roughly 20-25,000 new cases per year in the United States and it is increasing for some reason.

12 Feb 2013

Individualized flu immune responses revealed by high-throughput sequencing

Researchers have shown that it is possible to create personalized, individual-specific measurements of the antibody repertoire in response to influenza vaccination using high-throughput DNA sequencing technology.

11 Feb 2013

Infusions of regulatory T cells turn off autoimmune attack on joints

Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved treatment of arthritis and other autoimmune disorders in people.

10 Feb 2013

Combination of two antibodies prevents growth and spread of triple-negative breast tumors

Cancer drugs of the new, molecular generation destroy malignant breast tumors in a targeted manner: They block characteristic molecules on tumor cells - receptors for the hormones estrogen or progesterone, or a co-receptor, called HER2, that binds to many growth factors. But about one in every six breast tumors has none of these receptors. Such cancers, called triple-negative, are particularly aggressive and notoriously difficult to treat.

10 Feb 2013

Top prostate cancer surgeon to conduct free men's health screening

On Saturday, February 16, 2013, top prostate cancer surgeon, Dr. David Samadi , will conduct free prostate cancer screenings at the Chian Federation, 4401 Broadway in Astoria, New York 11103.

10 Feb 2013

Rekom Biotech designs new biomarkers that can identify West Nile virus, dengue

Researchers at the University of Granada have designed a set of biomarkers that can be used in diagnostic tests for the detection of dengue and the West Nile virus, two infectious diseases transmitted by the bite of a mosquito. These biomarkers can be used to identify these viral diseases, which affect millions of people worldwide.

9 Feb 2013

First new TB vaccine in century fails initial testing

The first of a series of new vaccines that have been developed to combat tuberculosis failed to show efficacy compared with placebo in South African infants, show results from a phase II trial.

7 Feb 2013

Delayed hematuria common after prostate brachytherapy

A significant proportion of patients with prostate cancer who are treated with brachytherapy develop gross hematuria years later, report researchers.

4 Feb 2013

Cutting down on fried food could lower prostate cancer risk

Men who eat deep-fried food at least once a week may be increasing their risk for developing prostate cancer, show findings from a US study.

4 Feb 2013

Scientists produce monoclonal antibody in tobacco plants that neutralizes rabies viruses

Smoking tobacco might be bad for your health, but a genetically altered version of the plant might provide a relatively inexpensive cure for the deadly rabies virus. In a new research report appearing in The FASEB Journal, scientists produced a monoclonal antibody in transgenic tobacco plants that was shown to neutralize the rabies virus.

2 Feb 2013

Seattle Genetics receives Health Canada approval for ADCETRIS to treat sALCL, Hodgkin lymphoma

Seattle Genetics, Inc. today announced that Health Canada has issued a Notice of Compliance with conditions (NOC/c), authorizing marketing of ADCETRIS for two lymphoma indications.

1 Feb 2013

Microbiologists discover new pathway to improve vaccines against tuberculosis

A new pathway for improving vaccines against tuberculosis has been discovered by microbiologists at the University at Buffalo in collaboration with researchers at other universities, according to a paper in the journal Mucosal Immunology, published by the Nature group.

1 Feb 2013

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

CEL-SCI Corporation announced that its longstanding collaboration with Northeast Ohio Medical University has produced a new investigational breast cancer vaccine which prevents and treats a HER-2/neu expressing breast cancer tumor in a mouse model of the disease.

31 Jan 2013

Positive results from PaxVax's Ad4-H5-Vtn vector vaccine Phase 1 trial on avian flu

PaxVax, Inc., which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced positive results in a Phase 1 clinical trial for its oral, replicating adenovirus serotype 4 (Ad4) vector vaccine for H5N1 (avian flu).

31 Jan 2013

NRC, AvidBiologics partner to develop three novel ADCs for treatment of cancer

AvidBiologics Inc., a life sciences company developing antibody-drug conjugates (ADCs), announces the conclusion of an agreement with the National Research Council Canada (NRC) to develop three novel ADCs for the treatment of cancer.

30 Jan 2013

OncoPep commences PVX-410 Phase 1/2a trial in smoldering multiple myeloma

OncoPep, Inc. today announced that the Company has initiated a Phase 1/2a clinical trial evaluating PVX-410, a multi-peptide therapeutic cancer vaccine, in patients with smoldering multiple myeloma, an asymptomatic precursor of multiple myeloma, which is an incurable cancer of the plasma cells.

30 Jan 2013

FDA allows IND application for ImmunoCellular’s ICT-140 to treat ovarian cancer

ImmunoCellular Therapeutics, Ltd. announced that the US Food and Drug Administration (FDA) has allowed the investigational new drug (IND) application for ICT-140, paving the way for conducting a clinical trial.

30 Jan 2013

Antigen News and Research

Study identifies regions of genes linked to Beh-et's disease

Allografts better survive implantation into brains of immunocompetent research mice

Antibody therapeutics targeting GPCRs to be developed by alliance between MorphoSys and Heptares

Metastatic renal cell carcinoma (mRCC) therapy: an interview with Charles A. Nicolette, Ph.D., CSO of Argos Therapeutics

Individualized flu immune responses revealed by high-throughput sequencing

Infusions of regulatory T cells turn off autoimmune attack on joints

Combination of two antibodies prevents growth and spread of triple-negative breast tumors

Top prostate cancer surgeon to conduct free men's health screening

Rekom Biotech designs new biomarkers that can identify West Nile virus, dengue

First new TB vaccine in century fails initial testing

Delayed hematuria common after prostate brachytherapy

Cutting down on fried food could lower prostate cancer risk

Scientists produce monoclonal antibody in tobacco plants that neutralizes rabies viruses

Seattle Genetics receives Health Canada approval for ADCETRIS to treat sALCL, Hodgkin lymphoma

Microbiologists discover new pathway to improve vaccines against tuberculosis

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

Positive results from PaxVax's Ad4-H5-Vtn vector vaccine Phase 1 trial on avian flu

NRC, AvidBiologics partner to develop three novel ADCs for treatment of cancer

OncoPep commences PVX-410 Phase 1/2a trial in smoldering multiple myeloma

FDA allows IND application for ImmunoCellular’s ICT-140 to treat ovarian cancer

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