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FDA grants priority review for Bayer HealthCare's riociguat for treatment of CTEPH

Bayer HealthCare announced today that the New Drug Application for its oral investigational compound riociguat has been accepted for filing and granted priority review by the U.S. Food and Drug Administration for the treatment of inoperable chronic thromboembolic pulmonary hypertension or with persistent or recurrent CTEPH after pulmonary endarterectomy and pulmonary arterial hypertension.

8 Apr 2013

Heart, blood and lungs have same receptors for sensing odors that exist in nose

In a discovery suggesting that odors may have a far more important role in life than previously believed, scientists have found that heart, blood, lung and other cells in the body have the same receptors for sensing odors that exist in the nose.

8 Apr 2013

Researchers discover new molecular mechanism to prevent edema formation

Researchers of the Max Delbr-ck Center for Molecular Medicine and the Leibniz Institute of Molecular Pharmacology in Berlin-Buch, Germany, have now detected a substance that can prevent the accumulation of fluid in body tissue and thus edema formation.

8 Apr 2013

AstraZeneca reports fostamatinib Phase 3 study results for treatment of rheumatoid arthritis

AstraZeneca today announced top-line results of OSKIRA-1, a Phase 3 study to assess the efficacy and safety of fostamatinib, the first oral spleen tyrosine kinase inhibitor in development for rheumatoid arthritis.

6 Apr 2013

HYFFI project examines positive effects of seaweed fibre on bacterial in human gut

Seaweeds are not only tasty, but they are a source of nutrients that could be beneficial for health and wellbeing. And like terrestrial plants, seaweeds also contain significant portions of fibre that reach the colon undigested. But does seaweed fibre have similar positive effects on bacterial in the human gut? That's the question that the HYFFI project, funded by the EU, is trying to solve.

6 Apr 2013

First Korean/U.S. workshop on drug regulation and marketing

Getting more and better drugs to market for patients was the ultimate goal of the University of Maryland School of Pharmacy's first Korean/U.S. workshop on drug regulation and marketing from March 18 to 22.

6 Apr 2013

Arena Pharmaceuticals kicks off APD334 Phase 1 clinical trial for treatment of autoimmune diseases

Arena Pharmaceuticals, Inc. announced today the initiation of dosing in a Phase 1 clinical trial of APD334, a novel oral drug candidate that targets the sphingosine 1-phosphate subtype 1 (S1P1) receptor for the potential treatment of autoimmune diseases.

6 Apr 2013

Research findings shed light on how neurons translate sensory input into actions

New research by scientists at the University of Massachusetts Medical School shows at the single cell level how an external stimulus sets off a molecular chain reaction in the transparent roundworm C. elegans, a process in which a single neurotransmitter coordinates and times two separate actions.

3 Apr 2013

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute have discovered that an imbalance between an enzyme called neutrophil elastase and its inhibitor causes inflammation, obesity, insulin resistance, and fatty liver disease.

3 Apr 2013

Researchers to test cyclodextrin for treating Niemann-Pick Type C disease

Washington University School of Medicine in St. Louis is playing a leading role in one of the National Institutes of Health's (NIH) first clinical trials to improve treatments for rare and neglected diseases.

3 Apr 2013

UC Davis scientists find mechanism in metabolized omega-3 fatty acid that helps combat cancer

A team of UC Davis scientists has found that a product resulting from a metabolized omega-3 fatty acid helps combat cancer by cutting off the supply of oxygen and nutrients that fuel tumor growth and spread of the disease.

3 Apr 2013

Mount Sinai experts to educate families on identifying signs, symptoms of ASD

The latest report from the US Centers for Disease Control and Prevention estimates that one out of 50 school-aged children has an autism spectrum disorder.

30 Mar 2013

Johns Hopkins scientists identify DNA-damaging substances in food

In a laboratory study pairing food chemistry and cancer biology, scientists at the Johns Hopkins Kimmel Cancer Center tested the potentially harmful effect of foods and flavorings on the DNA of cells.

28 Mar 2013

Neurological researchers study promising new treatment for deadly brain tumors

A promising new treatment for deadly brain tumors taken orally with minimal side effects is being studied by neurological researchers at Rush University Medical Center, Chicago.

28 Mar 2013

New analysis reveals online nutritional guidelines for cancer patients appear to be inconsistent

Radiation oncologists at Thomas Jefferson University Hospital are stressing the need for evidence-based, standardized guidelines on dietary recommendations for cancer patients—and with good reason.

27 Mar 2013

Ketamine may help treat severe depression, reduce suicidal urges, UAB researchers say

University of Alabama at Birmingham researchers think ketamine, an anesthesia medication in use since the 1970s, might be a valuable tool in treating severe depression and reducing suicidal urges; they have launched two studies to explore the possibility.

27 Mar 2013

Penn researchers develop nanotechnology-inspired technique for diagnosing Lyme disease

Early diagnosis is critical in treating Lyme disease. However, nearly one quarter of Lyme disease patients are initially misdiagnosed because currently available serological tests have poor sensitivity and specificity during the early stages of infection.

27 Mar 2013

Scientists discover novel compounds that can lead to new strategies for treating diseases

Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect.

26 Mar 2013

Researchers test protease inhibitors with potential for prevention, treatment of norovirus infection

A Kansas State University-led team is researching ways to stop the spread of norovirus, a contagious stomach illness that infects one in 15 Americans each year, according to the Centers for Disease Control and Prevention.

25 Mar 2013

Newly discovered molecule could form the basis of anti-malaria drugs

An international study, involving researchers from Griffith University's Eskitis Institute, has discovered a molecule which could form the basis of powerful new anti-malaria drugs.

25 Mar 2013

Compound News and Research

FDA grants priority review for Bayer HealthCare's riociguat for treatment of CTEPH

Heart, blood and lungs have same receptors for sensing odors that exist in nose

Researchers discover new molecular mechanism to prevent edema formation

AstraZeneca reports fostamatinib Phase 3 study results for treatment of rheumatoid arthritis

HYFFI project examines positive effects of seaweed fibre on bacterial in human gut

First Korean/U.S. workshop on drug regulation and marketing

Arena Pharmaceuticals kicks off APD334 Phase 1 clinical trial for treatment of autoimmune diseases

Research findings shed light on how neurons translate sensory input into actions

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Researchers to test cyclodextrin for treating Niemann-Pick Type C disease

UC Davis scientists find mechanism in metabolized omega-3 fatty acid that helps combat cancer

Mount Sinai experts to educate families on identifying signs, symptoms of ASD

Johns Hopkins scientists identify DNA-damaging substances in food

Neurological researchers study promising new treatment for deadly brain tumors

New analysis reveals online nutritional guidelines for cancer patients appear to be inconsistent

Ketamine may help treat severe depression, reduce suicidal urges, UAB researchers say

Penn researchers develop nanotechnology-inspired technique for diagnosing Lyme disease

Scientists discover novel compounds that can lead to new strategies for treating diseases

Researchers test protease inhibitors with potential for prevention, treatment of norovirus infection

Newly discovered molecule could form the basis of anti-malaria drugs

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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