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New microRNA mechanism for regulating brain function

Non-coding regions of the genome - those that don't code for proteins - are now known to include important elements that regulate gene activity. Among those elements are microRNAs, tiny, recently discovered RNA molecules that suppress gene expression.

18 Jan 2006

Genetics plays a role in drug-seeking behavior

Inbred strains of rats differ in how aggressively they seek cocaine after a few weeks of use, researchers say.

18 Jan 2006

Leptin, brain and body weight

Researchers have identified a new area of the brain that responds to the fat hormone leptin in regulating body weight and energy expenditure. They said that the region seems to be particularly important in enabling the body to resist weight gain from a high-fat diet.

18 Jan 2006

How the brain recognizes objects

When a human looks at a number, letter or other shape, neurons in various areas of the brain's visual center respond to different components of that shape, almost instantaneously fitting them together like a puzzle to create an image that the individual then "sees" and understands

18 Jan 2006

Taste encoding in the brain

Instantly reacting to the sweet lure of chocolate or the bitter taste of strychnine would seem to demand that such behavioral responses be so innate as to be hard-wired into the brain.

18 Jan 2006

Retinal degeneration - researchers advance understanding

Researchers have labored for decades to understand blindness-inducing neurodegenerative diseases such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP).

18 Jan 2006

Alzheimer's may be triggered by neuron division

A new study in mice suggests that Alzheimer's disease (AD) may be triggered when adult neurons try to divide. The finding helps researchers understand what goes wrong in the disease and may lead to new ways of treating it.

18 Jan 2006

Segregation of the brain into gray and white matter

By borrowing mathematical tools from theoretical physics, scientists have recently developed a theory that explains why the brain tissue of humans and other vertebrates is segregated into the familiar "gray matter" and "white matter."

11 Jan 2006

Researchers uncover new toxic mechanism in ALS - Lou Gehrig's disease

Exactly how ALS - Lou Gehrig's disease - damages motor neurons is one of medical science's lingering mysteries. At least six mishaps within cells appear to contribute to the death of the nerves that enable muscle movement, but nothing stands out as the key problem.

6 Jan 2006

Evidence that the eye has complementary brain-signaling systems at work

A new retinal photoreceptor adjusts its sensitivity in different lighting conditions, according to scientists at Brown University, where the rare eye cells were discovered.

6 Jan 2006

Astrocytes play a direct role in controlling blood flow in the brain - influencing Alzheimer's

New findings that long-overlooked brain cells play an important role in regulating blood flow in the brain call into question one of the basic assumptions underlying today's most sophisticated brain imaging techniques and could open a new frontier when it comes to understanding Alzheimer's disease.

6 Jan 2006

Researchers discover brain mechanism involved with interpreting visual signals

Researchers from the University of Chicago have uncovered an important mechanism used by the developing brain to pattern nerve connections in the part of the brain that interprets visual signals.

5 Jan 2006

Researchers move closer to understanding the basis of a severe epilepsy and mental retardation

Researchers at the University of California, San Diego (UCSD) School of Medicine took a step closer to understanding the basis of a severe epilepsy and mental retardation syndrome with work published in the January 5, 2006 issue of the journal Neuron.

5 Jan 2006

Brain's endocannabinoids protects neurons from inflammation

Some clinical studies have indicated that marijuana or its active cannabinoid ingredient alleviates symptoms of the inflammatory disease multiple sclerosis (MS).

5 Jan 2006

Scientists discover how to integrate new neurons into the brain

In experiments with mice, scientists from Johns Hopkins' Institute for Cell Engineering have discovered the steps required to integrate new neurons into the brain's existing operations.

22 Dec 2005

Electrical microstimulation allows researchers to map the brain for the first time

Over the last two centuries electrical microstimulation has been often used to demonstrate causal links between neural activity and specific behaviors or cognitive functions. However, to understand the mechanisms by which electrical microstimulation can cause alternations in behaviors and cognitive functions it is imperative to characterize the cortical activity patterns that are elicited by stimulation locally around the electrode and in other functionally connected areas.

22 Dec 2005

Insight into how marajuana induced munchies works

Marijuana--or more specifically its active ingredient, tetrahydrocannabinol--has a well-documented tendency to stimulate hunger. And while scientists have traced this property to cannabinoid receptors in the brain, they have had little understanding of the neural circuitry underlying this effect.

22 Dec 2005