Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Stem cell biology and gene-editing techniques offer hope for kidney regeneration

Mini-kidney organoids have now been grown in a laboratory by using genome editing to re-create human kidney disease in petri dishes.

23 Oct 2015

Discovery may lead to development of cell-based regenerative therapy to restore thyroid function

A discovery made by investigators from Beth Israel Deaconess Medical Center and the Boston University School of Medicine may help lead to the development of a cell-based regenerative therapy which could be used to restore thyroid function in patients with cancer who have had their thyroids surgically removed and children born with congenital hypothyroidism.

23 Oct 2015

‘Dismal prognosis’ of blast-phase CML patients highlighted

A team of Mexican researchers reports on the poor outcomes of a large series of Mexican patients with chronic myeloid leukaemia in blast phase.

22 Oct 2015

NHS to produce unique stem cells that could revolutionize treatment for diabetic kidney disease

NHS Blood and Transplant will start producing stem cells for groundbreaking treatment aimed at combating one of the most serious health problems facing the NHS, diabetic kidney disease.

22 Oct 2015

RUCDR Infinite Biologics awarded $6 million grant from NINDS

The National Institute of Neurological Disorders and Stroke has awarded a five-year grant worth up to $6,034,323 to RUCDR Infinite Biologics, a unit of Rutgers' Human Genetics Institute of New Jersey. RUCDR, which is located on Rutgers' Busch Campus in Piscataway, is the world's largest university-based biorepository.

20 Oct 2015

Asterias’ Phase 1/2a study evaluates dose escalation of AST-OPC1 for cervical spinal cord injury

Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a biotechnology company focused on the emerging field of regenerative medicine, today announced that its Data Monitoring Committee has reviewed the initial safety data from all three patients in the first cohort and has recommended dose escalation to the second cohort.

20 Oct 2015

Stanford scientists identify a progenitor cell type that could repair damaged arteries

By tracking a single cell in a growing heart, scientists from Stanford University have discovered a cell type that could repair damaged arteries.

20 Oct 2015

New research seeks to improve understanding of how breast cancer starts

Dr Michalak was awarded a highly competitive, four-year career development fellowship from the National Breast Cancer Foundation for her research into breast stem cells. The funding is helping to further her research, which seeks to improve our understanding of how breast cancer starts.

20 Oct 2015

Low levels of stem cell factor associated with increased risk of cardiovascular disease

New research indicates that low levels of a growth factor called stem cell factor (SCF)--which is thought to be important for blood vessel repair--are linked with an increased risk of cardiovascular disease.

20 Oct 2015

Immatics, UTHealth to partner on cellular manufacturing for adoptive cellular therapy clinical trials

Immatics US, Inc., a subsidiary of Immatics Biotechnologies GmbH, and The University of Texas Health Science Center at Houston will collaborate on cellular manufacturing for adoptive cellular therapy (ACT) clinical trials.

19 Oct 2015

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

Investigators at Brigham and Women's Hospital and the Harvard Stem Cell Institute have established a highly efficient method for making kidney structures from stem cells that are derived from skin taken from patients.

19 Oct 2015

NYSCF, CBR collaborate to customize creation of high-quality stem cell lines

The New York Stem Cell Foundation and Cbr Systems, Inc. DBA Cord Blood Registry today announced a collaboration to customize the creation of high-quality stem cell lines. NYSCF will create induced pluripotent stem (iPS) cell lines from umbilical cord tissue collected after birth from healthy newborns provided by CBR.

19 Oct 2015

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

Neural stem cells transplanted into damaged brain sites in mice dramatically improved both motor and cognitive impairments associated with dementia with Lewy bodies, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

19 Oct 2015

Special CD4+ T cells appear to inhibit cancer growth, enhance tumor-killing powers of other immune cells

The key to immune-based cancer therapies lies in the ability to exploit some weakness within the tumor and its environment or to elude cancer's offenses. Writing in the journal Scientific Reports, researchers led by a group from the Roswell Park Cancer Institute Center for Immunotherapy have shared new insights about a subset of T cells that appear to do both those things, inhibiting cancer growth at the same time that they enhance the tumor-killing powers of other immune cells.

19 Oct 2015

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

A research conducted by Juan Méndez, Head of the DNA Replication Group of the Spanish National Cancer Research Centre (CNIO), sheds light on the molecular mechanisms of ageing of the stem cells responsible for regenerating blood cells and opens up a new avenue for reducing their progressive functional decline with age.

16 Oct 2015

New test could identify patients at risk of relapse from testicular cancer

Scientists have developed a new test to identify patients who are at risk of suffering a relapse from testicular cancer. Assessing just three features of a common kind of testicular cancer - called non-seminomatous germ cell tumour - can identify those at most at risk of relapse even where there is no evidence of tumour spread.

16 Oct 2015

US and German researchers team up to advance quality control of human stem cells

Researchers at The Scripps Research Institute (TSRI) in California, USA, and two German institutes, the Center for Integrated Psychiatry Kiel (ZIP) and the Fraunhofer Institute for Molecular Biology and Applied Ecology IME, have announced a partnership to advance the quality control of human stem cells.

16 Oct 2015

Researchers successfully convert skin cells into fully functional placenta-generating cells

Regenerative medicine is a new and expanding area that aims to replace lost or damaged cells, tissues or organs in the human body through cellular transplantation. Embryonic stem cells (ESCs) are pluripotent cells that are capable of long-term growth, self-renewal, and can give rise to every cell, tissue and organ in the fetus's body.

15 Oct 2015

Sleep deprivation can impact outcome of stem cell transplantation, study finds

Drowsy mice make poor stem cell donors, according to a new study by researchers at the Stanford University School of Medicine.

15 Oct 2015

CWRU investigator receives $2.82 million NIH grant to make stealth bombs for brain cancer treatment

A Case Western Reserve University researcher has received a 5-year, $2.82 million National Institutes of Health grant to make, in essence, stealth bombs that slip past the brain's defenses to attack an incurable form of cancer.

15 Oct 2015

Stem Cells News and Research

Further Reading

Stem cell biology and gene-editing techniques offer hope for kidney regeneration

Discovery may lead to development of cell-based regenerative therapy to restore thyroid function

‘Dismal prognosis’ of blast-phase CML patients highlighted

NHS to produce unique stem cells that could revolutionize treatment for diabetic kidney disease

RUCDR Infinite Biologics awarded $6 million grant from NINDS

Asterias’ Phase 1/2a study evaluates dose escalation of AST-OPC1 for cervical spinal cord injury

Stanford scientists identify a progenitor cell type that could repair damaged arteries

New research seeks to improve understanding of how breast cancer starts

Low levels of stem cell factor associated with increased risk of cardiovascular disease

Immatics, UTHealth to partner on cellular manufacturing for adoptive cellular therapy clinical trials

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

NYSCF, CBR collaborate to customize creation of high-quality stem cell lines

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

Special CD4+ T cells appear to inhibit cancer growth, enhance tumor-killing powers of other immune cells

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

New test could identify patients at risk of relapse from testicular cancer

US and German researchers team up to advance quality control of human stem cells

Researchers successfully convert skin cells into fully functional placenta-generating cells

Sleep deprivation can impact outcome of stem cell transplantation, study finds

CWRU investigator receives $2.82 million NIH grant to make stealth bombs for brain cancer treatment

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