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Minimally invasive surgery to alleviate the pain and pressure of sinusitis is a safe

Minimally invasive surgery to alleviate the pain and pressure of sinusitis is a safe, effective therapy for geriatric patients who can't be helped by medication alone, according to new research.

3 Jan 2005

Polycystic ovary syndrome (PCOS), the most common endocrine disorder among reproductive-age women

The polycystic ovary syndrome (PCOS), the most common endocrine disorder among reproductive-age women, produces a wide variety of body changes with both physical and emotional implications for sufferers.

3 Jan 2005

Pegaptanib (Macugen) is an effective treatment for neovascular age-related macular degeneration

Results from two concurrent, prospective, double-blind, multi-center clinical trials show that pegaptanib (Macugen), an anti-vascular endothelial growth factor therapy, is an effective treatment for neovascular age-related macular degeneration (AMD), according to a paper in the Dec. 30 issue of the New England Journal of Medicine. Macugen was approved by the Food and Drug Administration on Dec. 17.

30 Dec 2004

Elderly women with cervical cancer face double jeopardy

Elderly women with cervical cancer face double jeopardy. Not only does their advanced age decrease chances of survival, it also decreases the likelihood that they'll be given the most aggressive treatments for their disease, according to a study by researchers at Washington University School of Medicine in St. Louis.

28 Dec 2004

Patients with cancer detected on screening mammography undergo less toxic treatment

Women who have their breast cancers detected by physical examinations are at least twice as likely to undergo toxic treatments than those who have their cancer detected by mammography—regardless of the age of the woman, a new study shows.

28 Dec 2004

Chemotherapy lowers levels of antioxidants and micronutrients

Children undergoing chemotherapy for acute lymphoblastic leukemia (ALL) have significant changes in their antioxidant and micronutrient status which are related to their treatment outcomes, according to the results of a novel prospective study.

28 Dec 2004

Laser therapy may be considered by arthritis patients as a safe Vioxx alternative

Adverse events of long term medication with NSAIDs and particularly coxibs, has recently received much attention in the Vioxx matter. Consequently, Vioxx has been withdrawn and Prexige has been withheld from the market. The whole group of coxibs, are now under special observation by drug agencies in both Europe and the United States.

27 Dec 2004

Update on world antimalarial drug supply

On 8 November, the World Health Organization (WHO) announced a shortfall of artemether + lumefantrine, an artemisinin-based combination therapy (ACT) used to treat malaria, for the period between November 2004 and March 2005

26 Dec 2004

Evidence suggests that changes in the bacteria and fungi in the gastrointestinal tract can intensify the immune system's reaction to common allergens

If you want to avoid allergies or asthma, scientists at the University of Michigan Medical School suggest you start paying more attention to what's in your gut.

23 Dec 2004

Researchers can now inexpensively program the chemical synthesis of entire genes on a single microchip

Devices the size of a pager now have greater capabilities than computers that once occupied an entire room. Similar advances are being made in the emerging field of synthetic biology at the University of Houston, now allowing researchers to inexpensively program the chemical synthesis of entire genes on a single microchip.

23 Dec 2004

Pharmacogenomics, has the potential to spark a major, technology-driven restructuring of the health care and pharmaceuticals industries

Pharmacogenomics, the study of genetic variability in the way individuals respond to medicines, has the potential to spark a major, technology-driven restructuring of the health care and pharmaceuticals industries

21 Dec 2004

Certain leukemia oncogenes switch on genetic programs that govern self-renewal, a unique stem cell characteristic

Researchers have discovered that specific cancer-causing genes associated with leukemias can transform mature white blood cells into leukemic cells that have all the properties of stem cells.

21 Dec 2004

New way to reduce fat and cholesterol levels in the body

Just in time for the holidays, McGill researchers have identified a new way to reduce fat and cholesterol levels in the body. Their program, which combines consuming plant-derived sterols (or oils) with exercise, may benefit those who are at risk of coronary heart disease.

21 Dec 2004

The burgeoning Indian AIDS epidemic

India, home to one-sixth of the human race, has an AIDS epidemic. Five million Indians are living with HIV infection. The stakes are high; the government is racing against time.

21 Dec 2004

Cancer drug paclitaxel may reduce the adverse effects of Alzheimer's disease

In a preclinical efficacy trial, the cancer drug paclitaxel (Paxceed)–which exerts its effects by binding to and stabilizing microtubules inside cells–reduced the adverse effects of Alzheimer's disease (AD)-like pathology in a mouse model.

20 Dec 2004

Genzyme files for European approval of Myozyme for treatment of Pompe disease

Genzyme Corp. announced today that the European Medicines Agency (EMEA) has accepted its marketing authorization application for Myozyme(R) (alglucosidase alfa), an investigational enzyme replacement therapy for Pompe disease.

20 Dec 2004

Timing of radiation and antiangiogenic therapy impacts treatment effectiveness

Agents designed to attack blood vessels that feed a growing tumor are effective against tumor growth in laboratory experiments. However, results of early clinical trials with these inhibitors have not yet exhibited the same success observed in animal models.

20 Dec 2004

Size of myocardial infarct measured using MRI

In animal studies, researchers at Johns Hopkins have effectively used magnetic resonance imaging (MRI) to measure with 94 percent accuracy the size and amount of heart muscle damaged by a heart attack, known in medical terms as a myocardial infarct, or m.i., for short.

20 Dec 2004

Oral medication alitretinoin effective in treating moderate or severe hand dermatitis

Use of the oral medication alitretinoin was effective in treating moderate or severe hand dermatitis in nearly half of patients previously unresponsive to standard treatment, according to an article in the December issue of The Archives of Dermatology.

20 Dec 2004

Many women at high risk for breast cancer are foregoing tamoxifen

Many women at high risk for breast cancer are foregoing tamoxifen, the first FDA-approved drug for prevention of breast cancer, due to concerns about side effects, increased risk of other cancers, and lack of information, a new study by researchers in Boston shows. The study was published in the December 14 in the Journal of Clinical Oncology.

20 Dec 2004

Therapy News and Research

Minimally invasive surgery to alleviate the pain and pressure of sinusitis is a safe

Polycystic ovary syndrome (PCOS), the most common endocrine disorder among reproductive-age women

Pegaptanib (Macugen) is an effective treatment for neovascular age-related macular degeneration

Elderly women with cervical cancer face double jeopardy

Patients with cancer detected on screening mammography undergo less toxic treatment

Chemotherapy lowers levels of antioxidants and micronutrients

Laser therapy may be considered by arthritis patients as a safe Vioxx alternative

Update on world antimalarial drug supply

Evidence suggests that changes in the bacteria and fungi in the gastrointestinal tract can intensify the immune system's reaction to common allergens

Researchers can now inexpensively program the chemical synthesis of entire genes on a single microchip

Pharmacogenomics, has the potential to spark a major, technology-driven restructuring of the health care and pharmaceuticals industries

Certain leukemia oncogenes switch on genetic programs that govern self-renewal, a unique stem cell characteristic

New way to reduce fat and cholesterol levels in the body

The burgeoning Indian AIDS epidemic

Cancer drug paclitaxel may reduce the adverse effects of Alzheimer's disease

Genzyme files for European approval of Myozyme for treatment of Pompe disease

Timing of radiation and antiangiogenic therapy impacts treatment effectiveness

Size of myocardial infarct measured using MRI

Oral medication alitretinoin effective in treating moderate or severe hand dermatitis

Many women at high risk for breast cancer are foregoing tamoxifen

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