Genes News and Research

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Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types - say, heart, liver, blood, and sperm cells - possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Fetal cell program appears to protect against acute myeloid leukemia

During the fetal stage, a number of so-called cell programs run that are vital to the development of the fetus.

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

395 genes found to be differently expressed in people with type 2 diabetes

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion.

20 Feb 2023

Utilizing CRISPR to discover new therapy options for COPD

In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies.

From Society for Laboratory Automation and Screening (SLAS) 20 Feb 2023

In-depth assessment of muscle biopsies in patients with long COVID

Researchers analyzed skeletal muscle biopsies of patients with persistent fatigue and malaise post-exertion to determine the underlying mechanisms of long COVID.

20 Feb 2023

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

In a recent study published in the journal Eurosurveillance, researchers investigated whether prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or coronavirus disease 2019 (COVID-19) vaccination protected against SARS-CoV-2 Omicron variant of concern (VOC) BA.4/5 sub-VOC or BA.2 sub-VOC infections.

19 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Metabolic engineering is a field of plant biotechnology that seeks to genetically modify plant metabolic pathways to generate plant varieties with improved health benefits.

17 Feb 2023

Scientists discover how a "poisoned" form of protein could spur cancer formation

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers.

17 Feb 2023

Differences in gut microbiome diversity attributed to dietary patterns in children with obesity

Differences in the dietary patterns of overweight or obese children contribute to variations in the gut microbiome diversity.

16 Feb 2023

A new trial to assess if butyrate can prevent colon cancer

Researchers discuss a new clinical trial that will determine the efficacy of butyrate administration in preventing colon cancer.

16 Feb 2023

Understanding neural crest cell development will help to better comprehend craniofacial birth defects

Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations.

16 Feb 2023

Genetic features of the immune system linked to a person's ability to resist new COVID-19 variants

An international team including researchers from the HSE University Faculty of Biology and Biotechnology has found a link between certain genetic features of the immune system and one's ability to effectively resist new waves of COVID-19.

16 Feb 2023

Similar genes may lead to different patterns of fat distribution in women

Obesity causes many health problems and worsens several chronic illnesses, including type 2 diabetes and cardiovascular disease, however, some obese people are more susceptible to complications than others.

16 Feb 2023

Genes encoding T cell receptors vary greatly between persons and populations, study reveals

Researchers from Karolinska Institutet have discovered that the genes encoding our T cell receptors vary greatly between persons and populations, which may explain why we respond differently to for example infections.

16 Feb 2023

Study provides insight into the immune microenvironment around Hodgkin lymphoma tumors

The most comprehensive study to date of the blood cancer, Hodgkin lymphoma, has provided fascinating insights into what tumour cells must do to survive. Researchers from the Wellcome Sanger Institute found that cancer cells use signals to attract certain types of immune cell and instruct them not to attack.

16 Feb 2023

Genes News and Research

Step-by-step process of rewiring cells to generate germ cell precursors

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

First fully human ovarian organoids provide insights about female reproductive health and disease

Fetal cell program appears to protect against acute myeloid leukemia

HKU research advances understanding of the fundamental biological processes of gene regulation

395 genes found to be differently expressed in people with type 2 diabetes

Utilizing CRISPR to discover new therapy options for COPD

In-depth assessment of muscle biopsies in patients with long COVID

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

Genome editing prevents hypertrophic cardiomyopathy in mice

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Scientists discover how a "poisoned" form of protein could spur cancer formation

Differences in gut microbiome diversity attributed to dietary patterns in children with obesity

A new trial to assess if butyrate can prevent colon cancer

Understanding neural crest cell development will help to better comprehend craniofacial birth defects

Genetic features of the immune system linked to a person's ability to resist new COVID-19 variants

Similar genes may lead to different patterns of fat distribution in women

Genes encoding T cell receptors vary greatly between persons and populations, study reveals

Study provides insight into the immune microenvironment around Hodgkin lymphoma tumors

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