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Study finds rise in volumes and survival after hematopoietic cell transplants among racial/ethnic minorities

The volume of hematopoietic cell transplants rose among all racial/ethnic groups, but grew faster among African Americans and Hispanics compared with Non-Hispanic white individuals, mirroring changes in population growth rates.

25 Apr 2024

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine announces that it has received approval from the U.S. Food and Drug Administration for its Investigational New Drug application for ISM3412, a small molecule inhibitor of MAT2A for the potential treatment of MTAP deleted cancers designed with Insilico's generative AI platform.

25 Apr 2024

Advancing medical treatment with causal machine learning

Machines can learn not only to make predictions, but also to handle causal relationships. An international research team shows how this could make therapies safer, more efficient, and more individualized.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Reduction of prenatal depression associated with higher full-term birth rates

The effect of lowering prenatal mother depression on gestational duration.

25 Apr 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

Paclitaxel treatment found to directly promote HBV replication and transcription

Hepatitis B virus (HBV) reactivation is commonly observed in individuals with chronic HBV infection undergoing antineoplastic drug therapy.

24 Apr 2024

Giant virus takes down deadly brain parasite

The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an international collaboration, have discovered viruses that infect this harmful microbe.

24 Apr 2024

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

Advanced insulin pumps enhance blood sugar management in type 1 diabetes

Blood sugar levels improve when adults with type 1 diabetes use modern insulin pumps. These are the findings of a study conducted at the University of Gothenburg.

24 Apr 2024

World Asthma Day 2024 Webinar: How embracing FeNO Testing can Transform Asthma Care

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From NObreath 24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

Study highlights nutrition therapy's potential to manage gestational diabetes effectively

Study investigates the effects of medical nutrition therapy on gestational diabetes mellitus, emphasizing the beneficial roles of specific dietary patterns and nutrient supplements in managing this condition effectively.

23 Apr 2024

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Study assesses global discrepancies in COVID-19 management guidelines across WHO member states, revealing that many national guidelines do not fully align with WHO recommendations, especially in lower-resource countries.

23 Apr 2024

Innovative peptide-based hydrogel therapy for virus prevention

Vaccines remain the gold standard of protection against dangerous pathogens, but take considerable time and vast resources to develop.

23 Apr 2024

Study reveals financial impact of cancer diagnosis on working-age adults in the U.S.

A new study led by researchers at the American Cancer Society (ACS) highlights the lasting financial impact of a cancer diagnosis for many working-age adults and their families in the United States.

23 Apr 2024

American Heart Association launches initiative to engage pharmacists in atrial fibrillation care

Atrial fibrillation, or AFib, is the most common type of irregular heartbeat, estimated to affect about 12.1 million U.S. adults by 2030.

23 Apr 2024

Undernourished household contacts three times more likely to develop TB

Mycobacterium tuberculosis, the bacteria that causes tuberculosis (TB), is distinct from most germs in its capacity to silently infect individuals for months and even years before waking up and causing active disease that can lead to severe illness and death.

23 Apr 2024

Social media messages may sway young people's beliefs about mental illness

Even subtle differences in the wording of social media messages may be enough to sway young people's beliefs about depression and anxiety and their treatment.

23 Apr 2024

Therapy News and Research

Study finds rise in volumes and survival after hematopoietic cell transplants among racial/ethnic minorities

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Advancing medical treatment with causal machine learning

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Reduction of prenatal depression associated with higher full-term birth rates

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

Paclitaxel treatment found to directly promote HBV replication and transcription

Giant virus takes down deadly brain parasite

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Advanced insulin pumps enhance blood sugar management in type 1 diabetes

World Asthma Day 2024 Webinar: How embracing FeNO Testing can Transform Asthma Care

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Study highlights nutrition therapy's potential to manage gestational diabetes effectively

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Innovative peptide-based hydrogel therapy for virus prevention

Study reveals financial impact of cancer diagnosis on working-age adults in the U.S.

American Heart Association launches initiative to engage pharmacists in atrial fibrillation care

Undernourished household contacts three times more likely to develop TB

Social media messages may sway young people's beliefs about mental illness

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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