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Analysis shows Remicade reduces pain associated with Crohn's disease

According to a new sub-analysis from the ACCENT I (A Crohn's disease Clinical trial Evaluating infliximab in a New long-term Treatment regimen) trial patients who received a three-dose induction regimen of Remicade experienced a significantly greater reduction in pain as assessed by four different pain questions after ten weeks, compared with patients who received a single dose of Remicade.

2 Nov 2004

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

Maxim Pharmaceuticals has announced that based upon the negative outcome of it's confirmatory Phase 3 clinical trial (M0104) studying Ceplene(TM) (histamine dihydrochloride) in combination with Interleukin-2 (IL-2) in advanced malignant melanoma patients with liver metastases, it plans to close the treatment protocol approved by the FDA earlier this year.

2 Nov 2004

High-dose statin therapy for aggressive cholesterol-lowering outperforms typical care

Patients treated with high doses of atorvastatin had about a one percent lower annual rate of heart attacks than similar patients receiving usual care, according to a new study in the Nov. 2, 2004 issue of the Journal of the American College of Cardiology.

2 Nov 2004

Studies show Pfizer's Azithromycin Microspheres effective as treatment for respiratory tract infections

Pfizer Inc.'s new investigational microsphere formulation of azithromycin, which is dosed as a one-time-only oral antibiotic, is comparable to other frequently prescribed treatments for some of the most common respiratory tract infections in adult patients.

1 Nov 2004

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

Improved risk classification for patients with acute lymphoblastic leukemia (ALL), coupled with more intensive intrathecal chemotherapy for high risk patients and the use of a drug called dexamethasone, could one day permit physicians to omit irradiation as a part of routine treatment.

1 Nov 2004

New approaches for the treatment of chronic hepatitis C

Data from two ongoing studies testing new approaches for the treatment of chronic hepatitis C was presented at the annual meeting of the American Association for the Study of Liver Diseases (AASLD) this afternoon.

1 Nov 2004

Study results suggest that metronidazole and clindamycin differ in their effects on microbes in women with bacterial vaginosis

In the first study to directly compare the emergence of antibiotic resistance following topical treatment between two antibiotics routinely prescribed for a common vaginal infection, researchers from the Magee-Womens Research Institute have found antibiotic-resistant bacteria more likely to develop with the drug clindamycin than metronidazole.

1 Nov 2004

New treatment option for patients who have moderately active ulcerative colitis

Results of a study presented today by a Mayo Clinic physician at the 69th Annual Scientific Meeting of the American College of Gastroenterology (ACG) in Orlando, Fla., offer a new treatment option for patients who have moderately active ulcerative colitis.

1 Nov 2004

Emotion-focused therapy - pioneering new treatment for emotional trauma and depression

If fighting emotion with emotion sounds unconventional, that’s because it is. York University Psychology Professor Leslie Greenberg is one of only a handful of researchers on the cutting edge of treatment for psychological trauma and depression using emotion-focused therapy, or EFT – a treatment he pioneered.

1 Nov 2004

Do cholesterol-reducing drugs decrease the risk of heart attacks and strokes in diabetics?

International researchers will, for the first time, present findings from the landmark 4D trial about whether a cholesterol-reducing drug decreases the risk of heart attacks and strokes with type 2 diabetics on dialysis at the American Society of Nephrology’s 37th Annual Meeting and Scientific Exposition in St. Louis, Missouri.

1 Nov 2004

Hormone therapy findings suggest a complex relationship between marketing, scientific evidence and prescribing patterns

Pharmaceutical companies slashed their promotional spending for hormone therapies by more than a third following reports in July 2002 of health risks associated with the drugs, but within the year they beefed up their marketing efforts to promote lower-dose forms of the medications

1 Nov 2004

Gene silencing may provide hope for leukemia sufferers

Ever since the approval of Gleevec in 2001, a cancer-cell-specific drug used to treat chronic myelogenous leukemia (CML), the field of cancer therapeutics has been rushing full speed into the era of so-called "targeted" medicines.

1 Nov 2004

Pegasys with ribavirin combo may best for reducing hepatitis C viral levels

Interim study results indicate a certain drug combination treatment may suppress the hepatitis C virus more quickly than another.

1 Nov 2004

Infants born to women with Inflammatory Bowel Disease (IBD), no more likely to develop congenital malformations

Infants born to women with Inflammatory Bowel Disease (IBD) are no more likely to develop congenital malformations than infants born to healthy mothers, according to a study presented at the 69th Annual Scientific Meeting of the American College of Gastroenterology.

1 Nov 2004

New therapy under development for the treatment of irritable bowel syndrome

A new therapy under development for the treatment of irritable bowel syndrome with diarrhea predominance appears to provide significant improvements in measures of quality of life, according to a study presented at the 69th Annual Meeting of the American College of Gastroenterology.

1 Nov 2004

Electroconvulsive therapy improves quality of life in patients with major depression

Electroconvulsive therapy (ECT) improves mood, quality of life and activities of daily living in patients with major depression, according to researchers at Wake Forest University Baptist Medical Center.

1 Nov 2004

Discovery affirms potential of stem cells for the development of possible therapies for spinal cord injury and nervous system disorders

Researchers at The Hospital for Sick Children (Sick Kids) have shown that stem cells found in adult skin retain their embryonic capability of making many types of cells.

1 Nov 2004

Uterine fibroid treatment option 'safe and effective'

Boston Scientific Corporation today welcomed an announcement by the Interventional Procedures Advisory Committee (IPAC) of the National Institute for Clinical Excellence (NICE), confirming the safety and efficacy of uterine fibroid embolization (UFE), an innovative treatment for fibroids.

1 Nov 2004

First ever study in hemodialysis patients to show stable hemoglobin levels

New data confirm that subcutaneous injection of the innovative new anti-anemia agent CERA (Continuous Erythropoietin Receptor Activator) delivers rapid, sustained and stable correction of anemia in a broad spectrum of patients with chronic kidney disease at dosing intervals of up to 4 weeks.

1 Nov 2004

Alimta approved as first treatment for Mesothelioma, a deadly cancer caused by asbestos

Lilly UK announced today that Alimta( (pemetrexed) will be available shortly for the treatment of people diagnosed with mesothelioma, a cancer of the lining of the lungs for which there is no known cure. Pemetrexed is the first licenced treatment for malignant pleural mesothelioma, in combination with cisplatin.

1 Nov 2004

Therapy News and Research

Analysis shows Remicade reduces pain associated with Crohn's disease

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

High-dose statin therapy for aggressive cholesterol-lowering outperforms typical care

Studies show Pfizer's Azithromycin Microspheres effective as treatment for respiratory tract infections

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

New approaches for the treatment of chronic hepatitis C

Study results suggest that metronidazole and clindamycin differ in their effects on microbes in women with bacterial vaginosis

New treatment option for patients who have moderately active ulcerative colitis

Emotion-focused therapy - pioneering new treatment for emotional trauma and depression

Do cholesterol-reducing drugs decrease the risk of heart attacks and strokes in diabetics?

Hormone therapy findings suggest a complex relationship between marketing, scientific evidence and prescribing patterns

Gene silencing may provide hope for leukemia sufferers

Pegasys with ribavirin combo may best for reducing hepatitis C viral levels

Infants born to women with Inflammatory Bowel Disease (IBD), no more likely to develop congenital malformations

New therapy under development for the treatment of irritable bowel syndrome

Electroconvulsive therapy improves quality of life in patients with major depression

Discovery affirms potential of stem cells for the development of possible therapies for spinal cord injury and nervous system disorders

Uterine fibroid treatment option 'safe and effective'

First ever study in hemodialysis patients to show stable hemoglobin levels

Alimta approved as first treatment for Mesothelioma, a deadly cancer caused by asbestos

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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