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Medical ethics: an interview with Anita Silvers

Medical ethics assists healthcare professionals to make decisions respectful of persons who happen to be their patients.

13 Aug 2012

HDAC8 gene mutations cause Cornelia deLange syndrome

Genetics researchers have identified a key gene that, when mutated, causes the rare multisystem disorder Cornelia deLange syndrome (CdLS). By revealing how mutations in the HDAC8 gene disrupt the biology of proteins that control both gene expression and cell division, the research sheds light on this disease, which causes intellectual disability, limb deformations and other disabilities resulting from impairments in early development.

13 Aug 2012

Highlights: New reports of problems at Parkland Hospital in Dallas; Mammogram rates did not rise under expanded Mass. coverage

Federal safety monitors produced a harsher critique of Parkland Memorial Hospital's reform efforts than recently portrayed by the hospital, finding ongoing dangers to patients from a botched surgery, medication errors and emergency care failures. Those problems, cited in a June compliance report obtained by The Dallas Morning News, were not disclosed in a Parkland summary released to The News two weeks ago.

12 Aug 2012

Longer looks: Waking up to the need for sleep

Among the more than 11,000 dearly departed inhabitants of Southeast Portland's Multnomah Park Cemetery, friends Eric Cordingley and David Anderson have their favorites: a reputed French madam, a young Norwegian institutionalized for being gay, and Louis Napoleon Lepley -- or, as they call him, "Louis the cannibal." Intriguing as their individual stories may be, together they help tell a bigger, darker tale

10 Aug 2012

Worldwide data reveal gaps in elderly eye care

Worldwide eye examination rates among older adults are very low, despite this age group being recommended to have an eye test at least every 1–2 years, say researchers from Canada.

10 Aug 2012

Patient, not surgeon factors influence patient-centric outcomes after knee surgery

Patient factors are more important than anything surgeons can control during total knee replacement surgery in the prediction of patient-reported outcome measures, report UK researchers.

9 Aug 2012

Organ donation: an interview with David Shaw

Most donors die in intensive care units, frequently after car accidents. Once it is clear that recovery is out of the question, families will be told that further treatment is futile and the issue of donation can be sensitively raised.

9 Aug 2012

Clinical trials to test safety of 3K3A-APC in patients with ischemic stroke

Clinical trials start this week for a stroke drug initially created by a team led by scientists at The Scripps Research Institute and the University of Southern California (USC), and further developed by biotech company ZZ Biotech.

9 Aug 2012

Abacus, SurePoint Medical partner to offer diabetes-care plan for employers

SurePoint Medical, provider of direct-to-consumer healthcare supplies and disease-management services, today announced a strategic partnership with Abacus Employer Health Solutions (Abacus) to offer its SurePoint Wellness diabetes-care plan to companies that use Abacus's Good Health Gateway employee health management program.

9 Aug 2012

Active Biotech, Teva to commence third Phase III study of laquinimod for RRMS

Teva Pharmaceutical Industries Ltd. and Active Biotech provided today an update on the clinical development program of once-daily oral laquinimod for the treatment of relapsing-remitting multiple sclerosis (RRMS).

9 Aug 2012

Plasma exchange is beneficial additive to optic neuritis treatment

The addition of plasma exchange to pulsed intravenous corticosteroid treatment of acute optic neuritis associated with neuromyelitis optica results in improved visual acuity, show study results.

8 Aug 2012

WSU researchers to test novel hypothesis that cardiolipin deficiency leads to disruption of TCA cycle

Barth Syndrome (BTHS) is a rare and serious genetic disorder that primarily affects males and is passed from mother to son; women who are carriers do not show symptoms of the disorder. Fifty percent of children born to a mother who is a carrier will inherit the defective gene, and all daughters born to an affected man will be carriers. BTHS is caused by a mutation in the tafazzin gene that results in decreased production of cardiolipin, an essential lipid for energy metabolism.

8 Aug 2012

About half of adults with type 2 diabetes experience acute and chronic pain

Almost half of adults with type 2 diabetes report acute and chronic pain, and close to one quarter report neuropathy, fatigue, depression, sleep disturbance and physical or emotional disability, according to a study of more than 13,000 adults conducted by researchers at the San Francisco VA Medical Center, the University of California, San Francisco and the Kaiser Permanente Division of Research in Oakland, CA. The researchers also found significant rates of shortness of breath, nausea and constipation.

8 Aug 2012

Scientists discover important neural mechanism underlying dyslexia

To participate successfully in life, it is important to be able to read and write. Nevertheless, many children and adults have difficulties in acquiring these skills and the reason is not always obvious. They suffer from dyslexia which can have a variety of symptoms. Thanks to research carried out by Bego-a D-az and her colleagues at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig, a major step forward has been made in understanding the cause of dyslexia.

8 Aug 2012

Risk of arteriovenous malformation bleeding is eight times higher during pregnancy

A new study supports what neurosurgeons have long suspected—that pregnancy is an important risk factor for bleeding from arteriovenous malformations (AVMs) in the brain, reports the August issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

8 Aug 2012

Study compares mortality rates among RA patients treated with individual TNF inhibitors

New research confirms no significant difference in the rates of death among patients with rheumatoid arthritis (RA) who were exposed to one of several TNF inhibitors used to treat RA, adalimumab (Humira), etanercept (Enbrel), and infliximab (Remicade).

8 Aug 2012

Post-discharge stroke coaching can help patients with their medications or recovery

When a stroke patient is discharged from the hospital, they often must cope with a new disability or lack of function, so changes in their medications or a new dosing prescription can be particularly confusing. This can lead the patient to overmedicate, take the wrong medication or skip medications entirely and can result in being readmitted to the hospital.

7 Aug 2012

Workers with disabilities more likely to experience injuries

A new study conducted by researchers at the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital and The Ohio State University compared medically attended noncccupational and occupational injuries among U.S. workers with and without disabilities.

7 Aug 2012

Creatine may fight major depression in women

Women battling stubborn major depression may have a surprising new ally in their fight—the muscle-building dietary supplement creatine.

7 Aug 2012

Biden seeks to allay veterans' concerns about benefits

Speaking at the Disabled American Veterans' national convention, Vice President Joe Biden reminded the group that veterans benefits were exempted from the automatic budget cuts that will be imposed on military and domestic programs as of Jan. 2. Meanwhile, President Barack Obama signed into law a legislative package that provides improved health care, housing, education and memorial services.

6 Aug 2012