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TSRI researchers awarded grant to develop novel method for detecting DNA damage in stem cells

A team at The Scripps Research Institute has won a $1,784,000 grant from the California Institute for Regenerative Medicine (CIRM). The funding will support the development of a new method for detecting DNA damage in stem cells to ensure that only the highest quality cells are used in transplantation or therapy.

31 Jan 2015

Rare respiratory virus could be linked to severe neurological illness in children

A cluster of children from Colorado in the USA have been treated for muscle weakness or paralysis that may be connected to a nationwide outbreak of a usually rare respiratory virus called enterovirus D68 (EV-D68), one of more than 100 non-polio enteroviruses.

31 Jan 2015

Adropin hormone offers a promising treatment option for type 2 diabetes

In a study published in Molecular Metabolism, a SLU researcher has found that adropin, a hormone that regulates whether the body burns fat or sugar during feeding and fasting cycles, can improve insulin action in obese, diabetic mice, suggesting that it may work as a therapy for type 2 diabetes.

30 Jan 2015

Sleep significantly affects memory organization in infant brain, shows study

There is no rest for a baby's brain - not even in sleep. While infants sleep they are reprocessing what they have learned.

29 Jan 2015

Study helps develop better understanding of how dopamine influences behaviour

Scientists studying hatchling fish have made a new advance in studying a chemical in the brain that impacts on movement.

29 Jan 2015

electroCore’s non-invasive vagus nerve stimulation therapy safe, effective across a variety of conditions

Non-invasive vagus nerve stimulation (nVNS) ‘improves the safety and tolerability of VNS making it more accessible and facilitating further investigations across a wide range of uses when compared with surgically implanted VNS’ according to a review in the European Journal of Neurology.

29 Jan 2015

Researchers receive DoD grant to develop new therapy against nerve agent exposure

University of Nebraska Medical Center researchers have received a $1.9 million grant from the Defense Threat Reduction Agency of the U.S. Department of Defense to develop a new therapy to protect military members from nerve agent exposure.

29 Jan 2015

Infants show consistent patterns of brain activity in response to painful vaccinations

Infants show distinct, consistent patterns of brain activity in response to painful vaccinations, reports a study in the February issue of PAIN, the official publication of the International Association for the Study of Pain.

28 Jan 2015

Progenitor cells responsible for generation and maintenance of Merkel cells

Researchers have identified a population of "progenitor" cells in the skin that are solely responsible for the generation and maintenance of touch-sensing Merkel cells. The study appears in The Journal of Cell Biology.

27 Jan 2015

Research findings may accelerate work to safely control diabetes

For those with diabetes, managing blood sugar is a balancing act -- if blood sugar is too high it raises the risk for nerve damage, blindness, kidney failure, and heart trouble, and if too low it can lead to a seizure or unconsciousness.

24 Jan 2015

International scientists take new path in epilepsy research

An international team of scientists together with the University of Bonn Hospital have taken a new path in the research into causes of epilepsy: The researchers determined the networks of the active genes and, like a dragnet, looked for the "main perpetrators" using a computer model.

24 Jan 2015

Gem Pharmaceuticals enrolls initial soft tissue sarcoma patients in GPX-150 Phase 2 clinical trial

Gem Pharmaceuticals announced today that the initial soft tissue sarcoma (STS) patients have been enrolled into the Company's Phase 2 clinical trial. This open-label study will assess the efficacy and safety of Gem's lead compound, GPX-150 (an investigational medication), in approximately 30 adults as first-line therapy for advanced or metastatic disease.

23 Jan 2015

New discovery may help doctors develop better treatments for brain, spinal cord injuries

In a discovery that could dramatically affect the treatment of brain and spinal cord injuries, researchers have identified a previously unknown, beneficial immune response that occurs after injury to the central nervous system.

23 Jan 2015

Scientists identify gene that helps regulate development of central nervous system

Scientists have identified a gene that helps regulate how well nerves of the central nervous system are insulated, researchers at Washington University School of Medicine in St. Louis report.

23 Jan 2015

DePuy Synthes announces launch of new CMF MatrixWAVE MMF System

The DePuy Synthes Companies of Johnson & Johnson today announced the launch of the DePuy Synthes CMF MatrixWAVE MMF System, an adaptable wave-patterned bone borne plate and screw system designed for use in the temporary stabilization of mandibular and maxillary fractures and osteotomies.

22 Jan 2015

Researchers identify promising new target for developing better therapies for neuroblastoma kids

Researchers at the University of Michigan's C.S. Mott Children's Hospital have identified a promising new target for developing new therapies for kids with high-risk neuroblastoma, according to a new study published in Molecular Cancer Research.

22 Jan 2015

Penn researchers make breakthrough on novel anesthetics

Penn Medicine researchers, in a continuation of their groundbreaking work to better understand how anesthesia works in the body, have found the first new class of novel anesthetics since the 1970s. Their findings, published in February issue of Anesthesiology, detail the processes through which the group uncovered these compounds.

21 Jan 2015

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

A somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for the first time, researchers at Penn's Abramson Cancer Center have found that the same mutated gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas (PCC/PGL) that become malignant.

21 Jan 2015

Study suggests link between neonatal ghrelin and obesity risk

Our subconscious motivation to eat is powerfully and dynamically regulated by hormone signals. The gut-derived hormone ghrelin is one such key regulator, promoting appetite through its effects on neurons in a small region of the brain called the hypothalamus.

21 Jan 2015

Johns Hopkins researchers propose novel cancer-fighting strategy

Existing cancer therapies are geared toward massacring tumor cells, but Johns Hopkins researchers propose a different strategy: subtly hardening cancer cells to prevent them from invading new areas of the body. They devised a way of screening compounds for the desired effect and have identified a compound that shows promise in fighting pancreatic cancer.

21 Jan 2015

Nerve News and Research

TSRI researchers awarded grant to develop novel method for detecting DNA damage in stem cells

Rare respiratory virus could be linked to severe neurological illness in children

Adropin hormone offers a promising treatment option for type 2 diabetes

Sleep significantly affects memory organization in infant brain, shows study

Study helps develop better understanding of how dopamine influences behaviour

electroCore’s non-invasive vagus nerve stimulation therapy safe, effective across a variety of conditions

Researchers receive DoD grant to develop new therapy against nerve agent exposure

Infants show consistent patterns of brain activity in response to painful vaccinations

Progenitor cells responsible for generation and maintenance of Merkel cells

Research findings may accelerate work to safely control diabetes

International scientists take new path in epilepsy research

Gem Pharmaceuticals enrolls initial soft tissue sarcoma patients in GPX-150 Phase 2 clinical trial

New discovery may help doctors develop better treatments for brain, spinal cord injuries

Scientists identify gene that helps regulate development of central nervous system

DePuy Synthes announces launch of new CMF MatrixWAVE MMF System

Researchers identify promising new target for developing better therapies for neuroblastoma kids

Penn researchers make breakthrough on novel anesthetics

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

Study suggests link between neonatal ghrelin and obesity risk

Johns Hopkins researchers propose novel cancer-fighting strategy

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