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Patent issued for generating genetically evolved mammalian cells through the regulation of mismatch repair

Morphotek announced today the issuance of United States Patent 6,825,038 covering the regulation of mismatch repair (MMR), a powerful process for generating functional diversity in mammalian cells, to yield sibs exhibiting desirable phenotypes for target discovery, drug screening and/or product development.

13 Dec 2004

Injectable gel that could speed repair of torn cartilage

In a project that will likely be watched by football players, runners and other athletes, researchers at MIT and Harvard Medical School say they are developing an injectable gel that could speed repair of torn cartilage, a common sports injury, and may help injured athletes return to competition sooner.

13 Dec 2004

Using precise, radioactively labeled genetic probes, researchers study cancer gene activity from outside the body

Using precise, radioactively labeled genetic probes, researchers at Jefferson Medical College have seen cancer gene activity from outside the body in laboratory mice. The probes, which work by attaching to genetic codes copied from an active cancer gene, may someday aid physicians and scientists in cancer detection and in determining the appropriate treatment for a cancer.

13 Dec 2004

Cell replacement therapy offers a novel and powerful medical technology

Cell replacement therapy offers a novel and powerful medical technology. A type of embryonic stem cell, called a neural crest stem cell, that persists into adulthood in hair follicles was recently discovered by Maya Sieber-Blum, Ph.D., of the Medical College of Wisconsin, Milos Grim, MD Ph.D., of Charles University Prague, and their collaborators.

13 Dec 2004

Need to correct racial disparities in health

The number of lives saved by medical advances over the last 10 years is far outdistanced by the number of lives lost to racial disparities in health status, according to a Virginia Commonwealth University family medicine and public health physician.

8 Dec 2004

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

An international consortium of scientists lead by Dr. James Paulson of The Scripps Research Institute has created a technology that will advance our understanding of the role of complex sugar chains (glycans or carbohydrates) that decorate the surface of cells in the body.

8 Dec 2004

Leg wounds can be accurately assessed using photographs taken at a patient's home

A pilot study has shown that leg wounds can be accurately assessed using photographs taken at a patient's home, adding one more example to a growing list of medical conditions that can be successfully monitored remotely.

8 Dec 2004

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Using hairlike microelectrodes and computer analysis, neurobiologists at Duke University Medical Center have demonstrated that they can see the detailed instant-to-instant electrical "brainscape" of neural activity across a living brain.

8 Dec 2004

DNA crystal that computes as it grows

In a demonstration that holds promise for future advances in nanotechnology, California Institute of Technology computer scientists have succeeded in building a DNA crystal that computes as it grows. As the computation proceeds, it creates a triangular fractal pattern in the DNA crystal.

7 Dec 2004

Revival of a unique and proven cancer treatment, neutron therapy

Northern Illinois University has announced plans to revive a unique and proven cancer treatment that blends advanced medical science with accelerator physics developed at Fermi National Accelerator Laboratory, a Department of Energy laboratory in Batavia, Ill.

7 Dec 2004

Non-invasive brain-computer interface offers more control than once thought

A brain-computer interface (BCI) that translates electrical signals detected from the scalp into a user's commands offers comparable precision, speed and accuracy to systems that rely on electrodes surgically implanted in the brain, researchers at the Department of Health's Wadsworth Center laboratories have shown.

7 Dec 2004

Ground breaking research in understanding the characteristics of human skin at very high frequencies

Ground breaking research in understanding the characteristics of human skin at millimetric waveband (MMW) frequencies is being conducted at Cranfield University – academic partner to the Royal Military College of Science at Shrivenham, Oxfordshire.

7 Dec 2004

Advanced wound care products to power expansion of European wound care market

The USD 1,111.1 million European wound care market is projected to gradually transition from traditional to advanced wound dressings. While traditional dressings currently dominate the total market, rising awareness of the clinical benefits provided by advanced wound dressings are set to widen their uptake.

7 Dec 2004

Scientist develops way to deliver promising genetic tool into living cells

By exploiting an HIV protein that readily traverses cell membranes, Carnegie Mellon University scientists have developed a new way to introduce a gene-like molecule called a peptide nucleic acid (PNA) directly into live mammalian cells, including human embryonic stem (ES) cells.

6 Dec 2004

MRI reveals similarities between the human and chimpanzee brain

New MRI-based studies present more evidence that the brains of chimpanzees are human-like in terms of the relationships among brain asymmetry, handedness and language, according to research undertaken at the Yerkes National Primate Research Center in Atlanta.

6 Dec 2004

Canadian experts gather to address emerging issues in immunization

More than 800 physicians, nurses, public health experts and researchers are gathering in Montreal this week for the sixth Canadian Immunization Conference, running Dec. 5-8, 2004. The conference is being hosted by the Public Health Agency of Canada and the Canadian Paediatric Society.

6 Dec 2004

Next-generation therapeutics with the potential to successfully treat Lou Gehrig's disease

The hopes of many that ALS (commonly referred to as Lou Gehrig's disease) will one day be a disease of the past, studied in medical textbooks, conquered by the dedication of those who have worked tirelessly to eradicate it might be realized in our lifetime.

6 Dec 2004

New technologies boost immunisation rates, safety

As global health leaders struggle to meet the United Nations goal of reducing mortality among the world's poorest children, vaccines are attracting more and more attention. The purchase of the vaccine is just the beginning, however, as the effectiveness of a vaccine is only as good as its delivery system.

6 Dec 2004

Positive results from phase 2 trial of Telintra, drug candidate in myelodysplastic syndrome

Telik, Inc. reported positive interim data from a Phase 2 trial of its Telintra (TLK199) drug candidate in myelodysplastic syndrome (MDS). The data were reported in two presentations at the annual meeting of the American Society of Hematology in San Diego.

5 Dec 2004

Genasense shown to enhance the anti-lymphoma activity of Velcade and Rituxan

Genta Incorporated announced that two new studies have shown that Genasense (oblimersen sodium) Injection, the Company's lead anticancer drug, showed synergistic activity with both bortezomib (Velcade; Millennium Pharmaceuticals, Inc.) and rituximab (Rituxan; Genentech, Idec) in experimental models of B-cell non-Hodgkin's lymphoma (NHL).

5 Dec 2004

Technology News and Research

Patent issued for generating genetically evolved mammalian cells through the regulation of mismatch repair

Injectable gel that could speed repair of torn cartilage

Using precise, radioactively labeled genetic probes, researchers study cancer gene activity from outside the body

Cell replacement therapy offers a novel and powerful medical technology

Need to correct racial disparities in health

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

Leg wounds can be accurately assessed using photographs taken at a patient's home

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

DNA crystal that computes as it grows

Revival of a unique and proven cancer treatment, neutron therapy

Non-invasive brain-computer interface offers more control than once thought

Ground breaking research in understanding the characteristics of human skin at very high frequencies

Advanced wound care products to power expansion of European wound care market

Scientist develops way to deliver promising genetic tool into living cells

MRI reveals similarities between the human and chimpanzee brain

Canadian experts gather to address emerging issues in immunization

Next-generation therapeutics with the potential to successfully treat Lou Gehrig's disease

New technologies boost immunisation rates, safety

Positive results from phase 2 trial of Telintra, drug candidate in myelodysplastic syndrome

Genasense shown to enhance the anti-lymphoma activity of Velcade and Rituxan

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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