Cell Metabolism News and Research

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Cervical tumors may be vulnerable to therapies that attack cancer's fuel supply, study shows

Cancer therapies have improved -- in some cases dramatically -- over the past two decades, but treatment for cervical cancer has remained largely unchanged. All patients receive radiation and chemotherapy, yet despite the aggressive approach, the regimen fails in about one-third of patients with cervical cancer that has spread beyond the cervix but not outside the pelvis.

15 Feb 2018

Salk scientists uncover how the liver can have a speedy response to food

Minutes after you eat a meal, as nutrients rush into your bloodstream, your body makes massive shifts in how it breaks down and stores fats and sugars.

9 Feb 2018

Study shows why insulin secretion does not work properly in type 2 diabetic individuals

In a new study, researchers from the universities of Uppsala and Lund show why insulin secretion is not working properly in patients suffering from type-2 diabetes.

6 Feb 2018

EXD2 enzyme facilitates protein production in mitochondria

Researchers from the Genomic Instability and Cancer Laboratory at Institute for Research in Biomedicine (IRB Barcelona) have identified a key role for EXD2 in protein production in the mitochondria, the cellular organelles responsible for the majority of energy generation.

17 Jan 2018

New 3-D imaging system offers insight into potential obesity and diabetes treatments

Researchers have developed A 3-D tissue imaging system that has revealed the inner workings of fat cells in mice, providing insight into potential therapeutic targets for combating obesity and diabetes.

10 Jan 2018

3D images of fat cells reveal potential targets to fight against obesity

Stunning three-dimensional images of fat cells, the first of their kind, are the latest tactic in the ongoing fight against the global obesity epidemic.

10 Jan 2018

Researchers discover promising drug that shrinks excess fat without lowering food intake

Given the ever-increasing obesity epidemic, researchers from The University of Texas Medical Branch at Galveston have discovered a promising developing drug that has been shown to selectively shrink excess fat by increasing fat cell metabolism.

4 Jan 2018

Specific diets may help prevent colorectal cancer in high-risk groups

Colorectal cancer is the most prevalent malignant tumor in Spain. It is known that factors such as diet and intestinal inflammation play an important role in its occurrence, but direct links between nutrients, inflammation and colorectal cancer are poorly described.

21 Dec 2017

Study reveals how caloric diet may reverse type 2 diabetes

A new study conducted on animal models at Yale University, revealed how type 2 diabetes could be rapidly reversed by use of a very low-calorie diet.

10 Nov 2017

Early intervention may be crucial to successful treatment of Friedreich's ataxia

New research published today in Disease Models & Mechanisms indicates that early intervention should be a key target in the development of new therapeutics for Friedreich's ataxia, as current treatments may be administered too late to target the disease effectively.

8 Nov 2017

New research disproves using anti-malaria drug for diabetes treatment

A drug used to treat malaria does not, after all, create new insulin-producing cells, according to a new paper from researchers at the University of California, Davis. The work, published in Cell Metabolism Nov. 2, refutes a study published in Cell in January.

3 Nov 2017

Study demonstrates beneficial effects of calorie-restricted diet in mice

Caloric restriction diets have been associated with various health benefits, but their effects on the skin have not been previously demonstrated. Research conducted at the University of São Paulo (USP) in Brazil shows that controlling calories helps mice live longer, although it reduces the reserves of fat in adipose tissue needed to keep the body warm.

30 Oct 2017

Researchers map molecular events that direct cells' energy metabolism down the cancerous path

As cells with a propensity for cancer break down food for energy, they reach a fork in the road: They can either continue energy production as healthy cells, or shift to the energy production profile of cancer cells.

24 Oct 2017

Brazilian scientists examine how benzopyrene can cause cancer

Benzo[a]pyrene is a potent carcinogen and mutagen present in cigarette smoke, automotive exhaust, burnt wood fumes, barbecued and smoked meat etc.

23 Oct 2017

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma.

23 Oct 2017

Study elucidates how obesity makes breast cancer more aggressive

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result. Scientists from Helmholtz Zentrum München, Technische Universität München, and Heidelberg University Hospital report on this in 'Cell Metabolism'. The team has already been able to halt this mechanism with an antibody treatment.

23 Oct 2017

Breakthrough discovery reveals positive correlation between sugar and cancer

A nine-year joint research project conducted by VIB, KU Leuven and VUB has led to a crucial breakthrough in cancer research.

13 Oct 2017

High fat diet linked to increased risk of relapse in kids with MS

On the other hand, high vegetable intake may halve the risk of relapse, the findings indicate. Several genetic and environmental factors, including previous infection with Epstein Barr virus, exposure to cigarette smoke, and low vitamin D levels have all been associated with a heightened risk of MS.

9 Oct 2017

Researchers propose LSD1 protein as central player in Alzheimer's and FTD

Removal of a regulatory gene called LSD1 in adult mice induces changes in gene activity that that look unexpectedly like Alzheimer's disease, scientists have discovered.

9 Oct 2017

Study provides insights into non-oncogenic addictions of tumors

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) and UC San Diego have shown that tumors can ensure a more reliable nutrient supply by eliminating the p62 protein in surrounding stromal tissue.

9 Oct 2017

Cell Metabolism News and Research

Cervical tumors may be vulnerable to therapies that attack cancer's fuel supply, study shows

Salk scientists uncover how the liver can have a speedy response to food

Study shows why insulin secretion does not work properly in type 2 diabetic individuals

EXD2 enzyme facilitates protein production in mitochondria

New 3-D imaging system offers insight into potential obesity and diabetes treatments

3D images of fat cells reveal potential targets to fight against obesity

Researchers discover promising drug that shrinks excess fat without lowering food intake

Specific diets may help prevent colorectal cancer in high-risk groups

Study reveals how caloric diet may reverse type 2 diabetes

Early intervention may be crucial to successful treatment of Friedreich's ataxia

New research disproves using anti-malaria drug for diabetes treatment

Study demonstrates beneficial effects of calorie-restricted diet in mice

Researchers map molecular events that direct cells' energy metabolism down the cancerous path

Brazilian scientists examine how benzopyrene can cause cancer

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Study elucidates how obesity makes breast cancer more aggressive

Breakthrough discovery reveals positive correlation between sugar and cancer

High fat diet linked to increased risk of relapse in kids with MS

Researchers propose LSD1 protein as central player in Alzheimer's and FTD

Study provides insights into non-oncogenic addictions of tumors

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