Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

Study gives insight into how signals enter cancer cells and drive aggressive growth

The outside of a cancer cell is bombarded by signals. They come from the immune system, supporting tissues and other structures. But how do those signals impact cancer?

14 May 2018

Study reveals the genetics underlying cerebral palsy and autism

Researchers from the Robinson Research Institute at the University of Adelaide have uncovered a genetic signal that is common to both cerebral palsy and autism.

10 May 2018

New research may help elucidate racial differences in prostate cancer

New research published in Molecular Oncology may help explain why African American men are at a higher risk of being diagnosed with prostate cancer and a higher risk of dying from the disease compared with European American men.

9 May 2018

Researchers discover how a light touch can lead to unbearable itching

For some people, particularly those who are elderly, even a light touch of the skin or contact with clothing can lead to unbearable itching.

4 May 2018

Mother's milk found to have SWAT team of immune cells

Immune cells that are ready to take action against invaders like bacteria have been found in women's breast milk, researchers say.

3 May 2018

Scientists discover culprit in reducing effectiveness of insulin

Scientists at Osaka University discovered that Stromal derived factor-1 (SDF-1) secreted from adipocytes reduced the effectiveness of insulin in adipocytes and decreased insulin-induced glucose uptake.

25 Apr 2018

Researchers use 'top-down proteomics' strategy to get new insights into cancer

When a RAS gene operates normally, it acts as an on/off switch for cell signaling to control cell proliferation. But when the gene mutates, the switch jams into the "on" position, allowing cells to proliferate uncontrollably.

18 Apr 2018

Removal of single mitochondrial protein leads to severe inflammation

The link between mitochondria and inflammation is still unclear. But it is known is that, for example, the accumulation of defective mitochondria, which should have been removed, causes inflammation.

10 Apr 2018

Study uncovers more complex, elaborate role for the body’s macromolecular complexes

Scientists at the National Institute on Drug Abuse Intramural Research Program have uncovered evidence that shows a more complex and elaborate role for the body's hard-working G protein-coupled receptors than previously thought, suggesting a conceptual advance in the fields of biochemistry and pharmacology.

28 Mar 2018

UH researchers improve understanding of autism spectrum disorders

Two University of Houston scientists are reporting that defects in a portion of the brain's hippocampus, called the dentate gyrus, is regulated by the nuclear receptor LXRβ (Liver X receptor Beta). The dentate gyrus, or DG, is responsible for emotion and memory and is known to be involved in autism spectrum disorders (ASD).

15 Mar 2018

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

Extremely low birth-weight babies are at risk for a chronic lung disease called bronchopulmonary dysplasia, or BPD.

9 Mar 2018

Researcher develops new technology for long-term stable neural recording

Klas Tybrandt, principal investigator at the Laboratory of Organic Electronics at Linköping University, has developed new technology for long-term stable neural recording. It is based on a novel elastic material composite, which is biocompatible and retains high electrical conductivity even when stretched to double its original length.

5 Mar 2018

Bioactive compound limits collateral damage in the kidneys after heart attack

A heart attack triggers an acute inflammatory response at the damaged portion of the heart's left ventricle. If this acute inflammation lingers, it can lead to stretching of the ventricle and heart failure. The inflammation can claim another victim -- the kidneys.

21 Feb 2018

Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Microcephaly, brain calcification, skeletal alterations, auditory and visual deficits - these are examples of the damage that can be caused by Zika virus in babies born to mothers infected during pregnancy.

2 Feb 2018

Human cardiac-muscle patches improve recovery from heart attack injury

Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals in a heart attack model. This clinically relevant approach showed that the patches significantly improved recovery from heart attack injury.

11 Jan 2018

Research reveals how Zika virus infection spurs fetal demise

A powerful antiviral protein may act as a checkpoint for keeping or ending a pregnancy.

5 Jan 2018

Newly solved glucagon receptor structure provides most accurate template for drug design

Class B G protein-coupled receptors (GPCRs) exert essential action in hormonal homeostasis and are important therapeutic targets for a variety of diseases including metabolic disorders such as type 2 diabetes.

4 Jan 2018

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Attempts to eradicate cancer are often compared to a "moonshot" -- the successful effort that sent the first astronauts to the moon.

3 Jan 2018

Study suggests potential means of stalling or even reversing diabetes-related blindness

Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness.

3 Jan 2018

FDA-approved drug to treat high blood pressure increases life span in worms

UT Southwestern Medical Center researchers find that an FDA-approved drug to treat high blood pressure seems to extend lifespan in worms via a cell signaling pathway that may mimic caloric restriction.

21 Dec 2017