Chromatin Immunoprecipitation (ChIP) News and Research

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Inhibiting mutant CHIP protein activity could decrease severity of ataxia disease symptoms

For the first time, the UNC School of Medicine lab of Jonathan Schisler, MS, PhD, linked the specific biochemical changes to a protein called CHIP to specific disease characteristics of patients with a wide range of rare disorders.

6 Nov 2019

Pioneering brain chip to fight opioid addiction: first US clinical test

Opioid addiction is among the biggest medical conditions troubling the U.S. today, and is far from reaching a solution. In 2017, it claimed almost 50 deaths per 100,000 in the state of West Virginia – the highest drug-overdose-related death rate in the US. Today, however, there is a gleam of hope from a new trial of an old technology to help fight this battle – a brain-embedded chip to counter opioid-induced cravings in treatment-refractory patients.

6 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

Return to sender: A single undeliverable letter can mean losing Medicaid

Forty-two boxes of returned mail lined a wall of the El Paso County Department of Human Services office on a recent fall morning. There used to be three times as many.

4 Nov 2019

MSU research team wins NIH grant to explore new way to study the gut's immune system

One day, instead of requiring a painful needle injection, vaccinating against a host of formerly fatal diseases could be as simple as swallowing a pill. But getting to that point means first gaining a better understanding of how the immune system works in the complex human gut, according to Montana State University researcher Diane Bimczok.

30 Oct 2019

Rice scientists take a step toward simplifying drug manufacture

With a lot of hard work and a dash of salt, Rice University scientists have taken a step toward simplifying drug manufacture.

29 Oct 2019

NYU researcher awarded $1.7 million NIH grant to optimize cancer treatment

Weiqiang Chen, assistant professor of biomedical engineering and mechanical and aerospace engineering at the NYU Tandon School of Engineering, has been awarded the Maximizing Investigators' Research Award (R35) from the National Institute of General Medical Sciences, a division of the National Institutes of Health.

29 Oct 2019

3D-printed cell traps help researchers remove the hay to expose cancer cells

Finding a handful of cancer cells hiding among billions of blood cells in a patient sample can be like finding a needle in a haystack. In a new approach enabled by 3D-printed cell traps, researchers are removing the hay to expose the cancer cells.

28 Oct 2019

Study finds molecular key to formation of mature and fully functioning T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.

25 Oct 2019

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

Today, the Global Virus Network, a conglomerate of 52 "Centers of Excellence" and 9 Affiliates in 32 countries, which catalyzes collaborative research into diseases caused by every class of virus in humans and animals, announced the Wyss Institute for Biologically Inspired Engineering at Harvard University as a new Center of Excellence.

24 Oct 2019

Easy evaluation of the mass flow meters SFM3xxx-AW and SFM3xxx-D

Sensirion, the worldwide leading manufacturer of high-quality flow and environmental sensors, is launching a new evaluation kit. With the EK-F3x-CAP, expiratory and proximal sensors of the SFM3xxx platform can be tested quickly and easily.

From Sensirion Inc 24 Oct 2019

Sensor platform for flow measurement in respiratory devices

Sensirion, the innovation driver and leading manufacturer of flow and environmental sensors, will be presenting its sensor platform for flow measurement in respiratory devices at the medical technology trade fair COMPAMED 2018.

From Sensirion Inc 24 Oct 2019

New liquid-cell technology provides first 3D view of life’s processes

A new liquid-cell technology allows scientists to see biological materials and systems in three dimensions under an electron microscope (EM), according to researchers at Penn State, Virginia Tech and Protochips Inc.

10 Oct 2019

Scientists solve a longstanding challenge in portable diagnostic devices

If you've ever stopped to watch rain falling on a windowpane, you've seen what happens when two drops of water touch and merge into one.

10 Oct 2019

Study finds why people crave more high-fat foods after a sleepless night

When you're sleep deprived, you tend to reach for doughnuts, fries and pizza. A new Northwestern Medicine study has figured out why you crave more calorie-dense, high-fat foods after a sleepless night -- and how to help thwart those unhealthy choices.

9 Oct 2019

Lack of sleep increases junk food cravings via nose-brain interactions

After a night without sleep, the hand reaches out almost automatically for anything rich, sweet and unhealthy – a change in food choice which could increase the body weight if practiced consistently over a significant period of time

9 Oct 2019

Discovery of neoantigens could widen the possibilities for universal cancer vaccine

For more than a decade, scientist Stephen Albert Johnston and his team at Arizona State University's Biodesign Institute have pooled their energies into an often scoffed-at, high-risk, high-reward goal in medicine: to develop a universal vaccine to prevent cancer.

2 Oct 2019

Duke Human Vaccine Institute participates in a large national effort to improve flu shots

As part of a massive national effort to improve and modernize flu shots, the Duke Human Vaccine Institute has received three research contracts from the National Institute of Allergy and Infectious Diseases, with an initial award of approximately $29.6 million in first-year funding.

30 Sep 2019

Insurers test new way to cut maternity care costs: Bundling

The thrill of delivering newborns helped pull Dr. Jack Feltz into the field of obstetrics and gynecology.

27 Sep 2019

New method can improve precision medicine, safety of drug-delivery devices

Researchers at the National Institute of Standards and Technology (NIST) have developed an optical system that accurately measures the flow of extraordinarily tiny amounts of liquids -- as small as 10 billionths of a liter (nanoliters) per minute.

27 Sep 2019