Craniofacial News and Research

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Fluoride consumption can cause mild enamel fluorosis

Young children who consume substantial amounts of fluoride through infant formula and other beverages mixed with fluoridated water or by swallowing fluoride toothpaste have an increased chance of developing mild enamel fluorosis, according to research published in the October issue of The Journal of the American Dental Association and supported by the National Institute of Dental and Craniofacial Research.

26 Oct 2010

Portrait painting may help children with craniofacial problems

A group of artists, young people and medical experts are involved in a groundbreaking project at The Children's Hospital of Philadelphia that uses the intimate process of portrait painting to help children and young people with craniofacial problems see themselves in a different light.

8 Oct 2010

Nasal CPAP machine may cause craniofacial changes

The use of a nasal continuous positive airway pressure (nCPAP) machine for more than 2 years may cause craniofacial changes in adults with obstructive sleep apnea (OSA).

5 Oct 2010

UIC develops new technique to anchor teeth back in jaw using stem cells

A new approach to anchor teeth back in the jaw using stem cells has been developed and successfully tested in the laboratory for the first time by researchers at the University of Illinois at Chicago.

30 Sep 2010

Mechanism behind gene mutation leading to development of cleft palate

Researchers from Mount Sinai School of Medicine have found a new mechanism that explains why a certain gene mutation causes craniofrontonasal syndrome (CFNS), a disorder that causes cleft palate and other malformations in the face, brain, and skeleton. Cleft palate affects one of every 1,000 newborns. The research is published in the September 15 issue of Genes & Development.

15 Sep 2010

Evaluation of medical reasons behind end to pregnancy due to abnormalities of fetus important

When a pregnancy ends tragically due to fatal abnormalities of the fetus, it is important to understand the medical reasons behind the event. This evaluation can help predict the risk of reoccurrence in future pregnancies. In the case of fetal akinesia deformation sequence (FADS), the fetus may have been affected by a disrupting injury or unavoidable maldevelopment.

18 Aug 2010

Thymosin beta 4 improves neurological functional outcome after embolic stroke: Researchers

RegeneRx Biopharmaceuticals, Inc. today announced a research team from the Henry Ford Hospital in Detroit, MI, reported that Thymosin beta 4, administered to rats after embolic stroke, improved neurological functional outcome compared to control animals.

20 Jul 2010

Subtle mutation affecting epigenome may lead to inherited form of mental retardation: Researchers

A subtle mutation affecting the epigenome –- a set of dynamic factors that influence gene activity -- may lead to an inherited form of mental retardation that affects boys, find researchers at Children's Hospital Boston. The disorder, which also involves cleft lip or cleft palate, appears to hinge on an enzyme working in a biological pathway that may offer several potential drug targets.

12 Jul 2010

BioDigital, NYU Langone partner to create Right Upper Lobe Resection Cognitive Task Trainer

SensAble Technologies, a leader in haptic devices and 3D modeling solutions, announced that its customer, BioDigital, working in partnership with surgeons at NYU Langone Medical Center, has created the first medical simulation application for teaching residents the high-technology procedure for lung resection of the right upper lobe, most commonly performed to treat resectable lung cancers.

23 Jun 2010

New book highlights specific aspects of salivary gland development

Salivary glands are of utmost importance for several physiological functions ranging from the protection of teeth and surrounding soft tissues to the lubrication of the oral cavity, which is crucial for speech and perception of food taste.

5 Jun 2010

Researchers assess influence of oral dimensions on MAS treatment success in patients with OSA

According to new research that will receive the Graduate Student Research Award on Saturday, June 5, at the 19th Annual Meeting of the American Academy of Dental Sleep Medicine, the ratio between tongue volume and bony enclosure size in patients with obstructive sleep apnea may help dentists calculate oral appliance treatment success.

5 Jun 2010

Study finds 18% of pediatric patients at-risk for sleep-related breathing disorders

According to new research that will be presented on Saturday, June 5, at the 19th Annual Meeting of the American Academy of Dental Sleep Medicine, an estimated 18 percent of pediatric patients in a University of North Carolina-based study were at-risk for sleep-related breathing disorders (SRBD). Importantly, pediatric risk was not associated with any demographic or craniofacial characteristics, as it is in adults, making it difficult to detect.

5 Jun 2010

New research: Questionnaires can help dentists screen for SDB in pediatric population

According to new research that will receive the Graduate Student Research Award on Saturday, June 5, at the 19th Annual Meeting of the American Academy of Dental Sleep Medicine, questionnaires can help dentists screen for sleep-disordered breathing in a pediatric population. SDB includes obstructive sleep apnea, upper-airway resistance syndrome, and snoring.

5 Jun 2010

Quality of life improves treatment of children with velocardiofacial syndrome: Research

Research about quality of life is improving the treatment of children with velocardiofacial syndrome, a chronic, genetic condition with a wide range of symptoms, including congenital heart disease, palatal abnormalities (e.g. cleft palate), and learning difficulties.

4 Jun 2010

U.S. Department of Defense OTT initiative to replace scars and defects with healthy, functional tissues

A two-year, $12 million contract with the U.S. Department of Defense Office of Technology Transition (OTT) will jumpstart human trials of three innovative research programs that aim to replace scars and defects with healthy, functional tissues, announced officials of the University of Pittsburgh and the McGowan Institute for Regenerative Medicine today at the Institute's Second Annual Open Session, Soldiers and Sailors Memorial Hall, Oakland.

31 May 2010

Folate supplementation thwarts heart birth defects induced by alcohol exposure in early pregnancy

A new animal study has found that high levels of the B-vitamin folate (folic acid) prevented heart birth defects induced by alcohol exposure in early pregnancy, a condition known as fetal alcohol syndrome.

25 May 2010

Tufts University's School of Arts and Sciences receives $9.5M grant to create research space

Tufts University's School of Arts and Sciences has received a $9.5 million grant to create research space that will house a Collaborative Cluster in Genome Structure and Developmental Patterning in Health and Disease.

17 May 2010

Study examines impact of tobacco smoke carcinogen on mice

Although tobacco use is widely understood to be one of the leading causes of oral cancer, research on the prevention of tobacco-related oral cancer in experimental animals has traditionally been limited to examining the impact of synthetic carcinogens manufactured especially for cancer research, rather than on observing the effects of carcinogens that occur in tobacco smoke.

14 May 2010

First 3-year results of world's largest temporomandibular joint disorder study reported at APS meeting

Scientists with the University of Maryland Dental School and collaborators at three other major universities will report results from the first three years of the world's largest study yet of a mysterious yet common pain syndrome involving the jaw at 8:30 a.m.on May 7 at the annual scientific meeting of the American Pain Society (APS). This year it is being held at the Baltimore Convention Center.

7 May 2010

AAA symposium features digital technologies in anatomical reconstruction

Techniques for using digital technology in separating conjoined twins, developing facial prostheses and acquiring data from anthropologic specimens will be among the topics presented at a symposium sponsored by the American Association of Anatomists (AAA; www.Anatomy.org) on April 28. The symposium is part of the Experimental Biology 2010 conference being held April 24-28, 2010 at the Anaheim Convention Center.

5 May 2010

Craniofacial News and Research

Fluoride consumption can cause mild enamel fluorosis

Portrait painting may help children with craniofacial problems

Nasal CPAP machine may cause craniofacial changes

UIC develops new technique to anchor teeth back in jaw using stem cells

Mechanism behind gene mutation leading to development of cleft palate

Evaluation of medical reasons behind end to pregnancy due to abnormalities of fetus important

Thymosin beta 4 improves neurological functional outcome after embolic stroke: Researchers

Subtle mutation affecting epigenome may lead to inherited form of mental retardation: Researchers

BioDigital, NYU Langone partner to create Right Upper Lobe Resection Cognitive Task Trainer

New book highlights specific aspects of salivary gland development

Researchers assess influence of oral dimensions on MAS treatment success in patients with OSA

Study finds 18% of pediatric patients at-risk for sleep-related breathing disorders

New research: Questionnaires can help dentists screen for SDB in pediatric population

Quality of life improves treatment of children with velocardiofacial syndrome: Research

U.S. Department of Defense OTT initiative to replace scars and defects with healthy, functional tissues

Folate supplementation thwarts heart birth defects induced by alcohol exposure in early pregnancy

Tufts University's School of Arts and Sciences receives $9.5M grant to create research space

Study examines impact of tobacco smoke carcinogen on mice

First 3-year results of world's largest temporomandibular joint disorder study reported at APS meeting

AAA symposium features digital technologies in anatomical reconstruction

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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