Gene Editing News and Research

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Ultra-precise gene therapy technologies could edit or silence faulty genes causing fatal heart diseases

An injectable cure for inherited heart muscle conditions that can kill young people in the prime of their lives could be available within a few years, after an international team of researchers were announced as the winners of the British Heart Foundation's Big Beat Challenge.

29 Jul 2022

Scientists receive $3.9 million NIH grant to eradicate HIV from the brain

Finding a cure for HIV has been extremely difficult, in part because the virus hides from antiretroviral treatments in one of the hardest places to reach: the brain.

27 Jul 2022

Using CRISPR to Lift the Lid on Probiotics

In this interview, we speak to Echo Pan, a Ph.D. student from North Carolina State University about her latest research that used CRISPR to uncover more on probiotics.

26 Jul 2022

Study clarifies the role of intestinal white blood cells in colorectal cancer

Colorectal tumors are swarming with white blood cells, but whether these cells help or hinder the cancer is hotly debated.

22 Jul 2022

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body.

19 Jul 2022

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Rice University researchers have demonstrated that CRISPR-Cas9, increasingly famous as a gene-editing tool, can be employed in powerful additional ways in human cells.

18 Jul 2022

Y chromosome loss in men can lead to deadly heart failure, research shows

The loss of the male sex chromosome as many men age causes the heart muscle to scar and can lead to deadly heart failure, new research from the University of Virginia School of Medicine shows.

14 Jul 2022

Researchers create a comprehensive map of how complex networks of genes function together

Using new technologies to study thousands of genes simultaneously within immune cells, researchers at Gladstone Institutes, UC San Francisco (UCSF), and Stanford School of Medicine have created the most detailed map yet of how complex networks of genes function together.

11 Jul 2022

Novel gene-based therapies for sickle cell disease rely on finding the right mouse for the job

Sickle cell disease is an extremely debilitating condition that affects up to 40% of the population in African countries, with patients suffering episodes of excruciating pain, organ damage and reduced life-expectancy.

7 Jul 2022

The Life Sciences; Where are we now, and where are we going?

As part of our SLAS Europe 2022 coverage, we spoke to Gerrit Gutzke and Michael Bussmann from Azenta Life Sciences about the products they offer for life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 7 Jul 2022

Study yields molecular clues that could lead to new treatments for rare genetic disease

A new stem cell study by KAUST researchers helps to explain a rare genetic disease called Wiskott-Aldrich syndrome (WAS), yielding molecular clues that could lead to new treatments for a devastating immune deficiency disorder.

6 Jul 2022

Study opens up a new avenue for the development of selective drug therapies

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

5 Jul 2022

HKUMed researchers discover more efficient CRISPR-Cas9 variants for gene therapy applications

A research team from the LKS Faculty of Medicine, The University of Hong Kong discovered more efficient CRISPR-Cas9 variants that could be useful for gene therapy applications.

30 Jun 2022

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" by scientists.

28 Jun 2022

Scientists identify new genetic disease that delays children's intellectual development

Scientists have identified a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development.

24 Jun 2022

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult.

24 Jun 2022

Cellular "barcoding" in mice unravels the origins of blood

The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications for blood cancers, bone marrow transplant, and immunology. Fernando Camargo, PhD, of the Stem Cell Program at Boston Children's Hospital led the study, published in Nature on June 15.

15 Jun 2022

Study describes how coronavirus subverts a host cell pathway to infect human cells

An international team of scientists, led by the University of Bristol, has been investigating how the SARS-CoV-2 virus, the coronavirus responsible for the COVID-19 pandemic, manipulates host proteins to penetrate into human cells.

15 Jun 2022

Using a harmless amoeba to protect children from dangerous infections

Innovative efforts at the University of Virginia School of Medicine to use a harmless amoeba to protect children from dangerous infections has won critical financial support from The Hartwell Foundation.

10 Jun 2022

University screening programs gave scientists early insights about omicron’s spread

Omicron was first reported in South Africa on Nov. 24, 2021, and within mere days it was already making the rounds in the United States, spiking SARS-CoV-2 case numbers as it infiltrated every school, restaurant, and family gathering. But when exactly did omicron unseat the delta variant to become dominant? And how quickly did it actually take over?

9 Jun 2022