Gene Editing News and Research

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Study uncovers why pesticide exposure increases Parkinson's disease risk in some people

A new University of Guelph study has discovered why exposure to pesticides increases some people's risk of developing Parkinson's disease.

24 May 2018

Mapping the Genes Responsible for Pluripotency

Dr. Atilgan Yilmaz and his team have developed a method by which they can produce haploid human embryonic stem cells from oocytes. They combined this technique with CRISPR-Cas9 to generate an atlas of the genome, containing the functions of over 18,000 genes.

23 May 2018

ToolGen's CRISPR/Cas9 gene editing platform improves T-cell anti-tumor activity in mouse model

ToolGen, Inc., a biotechnology company specializing in genome editing, today announced data demonstrating that blocking a molecular pathway that down-regulates T-cell activity with the Company’s CRISPR/Cas9 gene editing platform results in increased T-cell receptor signaling, in vitro, and in improved anti-tumor activity when tested against in a mouse glioblastoma tumor model.

22 May 2018

Scientists identify new drug target to combat chikungunya virus

Scientists have identified a molecule found on human cells and some animal cells that could be a useful target for drugs against chikungunya virus infection and related diseases, according to new research published in the journal Nature.

21 May 2018

Study provides insights into how immune cells kill bacteria with acid

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf every foreign object that crosses their way. After enclosing it in intracellular membrane vesicles, a process called phagocytosis, macrophages kill their prey with acid.

17 May 2018

Researchers discover mutation that can protect against Alzheimer's disease in mice

Researchers at the RIKEN Center for Brain Science have discovered a mutation that can protect against Alzheimer's disease in mice. Published in the scientific journal Nature Communications, the study found that a specific mutation can reduce the characteristic accumulation of the amyloid-beta peptide that occurs.

16 May 2018

UQ's new Genome Innovation Hub focuses on improving healthcare

Genetic research aimed at improving healthcare will be the focus of the University of Queensland’s new Genome Innovation Hub.

15 May 2018

CRISPR-based treatment can restore retinal function in mice with eye disease

Researchers from Columbia University have developed a new technique for the powerful gene editing tool CRISPR to restore retinal function in mice afflicted by a degenerative retinal disease, retinitis pigmentosa.

11 May 2018

UAB expert highlights need to do more trials in the epidemic center of disease

Frances Lund, Ph.D., the Charles H. McCauley Chair of Microbiology at the University of Alabama at Birmingham, spoke about chronic inflammatory disease and the striking correlation between location and disease incidence at the recent Fourth International Vatican Conference, "Unite to Cure."

11 May 2018

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Scientists have identified a mutation that gives cancer cells resistance to the breakthrough cancer treatment olaparib and other PARP inhibitors.

10 May 2018

New GP-write project to develop ultra-safe cells resistant to natural viruses

The Center for Excellence in Engineering Biology and the leadership of Genome Project-write today announced its first grand-scale community-wide project, to develop "ultra-safe cells" that resist natural viruses and potentially radiation, freezing, aging and cancer.

2 May 2018

BIO announces programming information for gene editing and synthetic biology at 2018 World Congress

The Biotechnology Innovation Organization (BIO) today announced programming information for gene editing and synthetic biology at the 2018 World Congress on Industrial Biotechnology.

28 Apr 2018

New UCLA study could elucidate certain causes of infertility and miscarriage

A new study in the journal Nature Cell Biology has uncovered information about a key stage that human embryonic cells must pass through just before an embryo implants. The research, led by UCLA biologist Amander Clark, could help explain certain causes of infertility and spontaneous miscarriage.

26 Apr 2018

Scientists use haploid stem cells to create an atlas of the human genome

Researchers have used a sophisticated gene-editing technology to create a new type of embryonic stem cell and an atlas of the human genome.

24 Apr 2018

Scientists use haploid stem cells to create an atlas of the human genome

Researchers have used a sophisticated gene-editing technology to create a new type of embryonic stem cell and an atlas of the human genome.

24 Apr 2018

Study examines how higher-order gene combinations help maintain normal cell physiology

We inherit many traits from our parents including the color of our eyes and hair. Unfortunately, we also inherit risk factors for certain diseases such as cancer, heart disease, and diabetes. Understanding those genetic connections can help prevention efforts and develop new life-saving treatments to combat these diseases.

20 Apr 2018

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

20 Apr 2018

New CRISPR tool allows DNA editing outside of the cell

Researchers have developed a cell free method of gene editing, which uses a new version of the CRISPR tool that can edit DNA outside of the cell. This technique could revolutionize cancer care.

20 Apr 2018

Genome editing identifies neural circuit behind leptin’s anti-obesity and anti-diabetes effects

Revealing surprising answers to a long-standing enigma about the brain target of the anti-obesity hormone leptin, neuroscientists at Tufts University School of Medicine have used CRISPR genome editing to identify a neural circuit in the hypothalamus as the primary mechanism in mediating leptin's anti-obesity and anti-diabetes effects and have identified two distinct mechanisms underlying leptin's inhibition of appetite.

19 Apr 2018

New faster, streamlined method for bowel cancer detection and treatment

Researchers at the South Australian Health and Medical Research Institute (SAHMRI) and the University of Adelaide have discovered a faster, more cost-effective way to determine which DNA mutations cause human bowel cancer.

17 Apr 2018